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The Herpes Simplex Virus Type 1 UL20 Protein Modulates Membrane Fusion Events during Cytoplasmic Virion Morphogenesis and Virus-Induced Cell Fusion

Journal of Virology, 2004-05, Vol.78 (10), p.5347-5357

2004

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UL20 Protein Functions Precede and Are Required for the UL11 Functions of Herpes Simplex Virus Type 1 Cytoplasmic Virion Envelopment

Journal of Virology, 2007-04, Vol.81 (7), p.3097-3108

2007

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Genetic analysis of the SARS-coronavirus spike glycoprotein functional domains involved in cell-surface expression and cell-to-cell fusion

Virology (New York, N.Y.), 2005-10, Vol.341 (2), p.215-230

2005

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Herpes Simplex Virus Type 1 Glycoprotein K and the UL20 Protein Are Interdependent for Intracellular Trafficking and trans-Golgi Network Localization

Journal of Virology, 2004-12, Vol.78 (23), p.13262-13277

2004

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Herpes Simplex Virus Type 1 gK Is Required for gB-Mediated Virus-Induced Cell Fusion, While neither gB and gK nor gB and UL20p Function Redundantly in Virion De-Envelopment

Journal of Virology, 2005-01, Vol.79 (1), p.299-313

2005

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Genetic Analysis of the Herpes Simplex Virus Type 1 UL20 Protein Domains Involved in Cytoplasmic Virion Envelopment and Virus-Induced Cell Fusion

Journal of Virology, 2004-07, Vol.78 (14), p.7329-7343

2004

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The herpes simplex virus UL20 protein functions in glycoprotein K (gK) intracellular transport and virus-induced cell fusion are independent of UL20 functions in cytoplasmic virion envelopment

Virology journal, 2007-11, Vol.4 (1), p.120-120, Article 120

2007

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Management of Pilomatrix Carcinoma: A Case Report of Successful Treatment with Mohs Micrographic Surgery and Review of the Literature

Dermatologic surgery, 2011-12, Vol.37 (12), p.1798-1805

2011

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Facial Port-Wine Stain: When to Worry?

Pediatric dermatology, 2012-01, Vol.29 (1), p.131-133

2012

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Effective treatment of human breast tumor in a mouse xenograft model with herpes simplex virus type 1 specifying the NV1020 genomic deletion and the gBsyn3 syncytial mutation enabling high viral replication and spread in breast cancer cells

Human gene therapy, 2007-05, Vol.18 (5), p.457

2007

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Clinical case of the month. A 48-year-old man with right lower extremity weakness and pain

The Journal of the Louisiana State Medical Society, 2010-09, Vol.162 (5), p.249

2010

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Genetics and functions of herpes simplex virus type 1 membrane proteins in virus-induced cell fusion, virion morphogenesis and egress

Melancon, Jeffrey M

2004

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Allosteric Modulation of Seven Transmembrane Spanning Receptors: Theory, Practice, and Opportunities for Central Nervous System Drug Discovery

Journal of medicinal chemistry, 2012-02, Vol.55 (4), p.1445-1464

2012

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Antipsychotic Drug-Like Effects of the Selective M4 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator VU0152100

Neuropsychopharmacology (New York, N.Y.), 2014-06, Vol.39 (7), p.1578-1593

2014

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Integrated nanotechnology platform for tumor-targeted multimodal imaging and therapeutic cargo release

Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (7), p.1877-1882

2016

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mGlu1-mediated restoration of prefrontal cortex inhibitory signaling reverses social and cognitive deficits in an NMDA hypofunction model in mice

Neuropsychopharmacology (New York, N.Y.), 2022-09, Vol.47 (10), p.1826-1835

2022

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Selective Activation of M4 Muscarinic Acetylcholine Receptors Reverses MK-801-Induced Behavioral Impairments and Enhances Associative Learning in Rodents

ACS chemical neuroscience, 2014-10, Vol.5 (10), p.920-942

2014

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Challenges in the development of an M 4 PAM in vivo tool compound: The discovery of VU0467154 and unexpected DMPK profiles of close analogs

Bioorganic & medicinal chemistry letters, 2017-01, Vol.27 (2), p.171-175

2017

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Targeted multifunctional gold-based nanoshells for magnetic resonance-guided laser ablation of head and neck cancer

Biomaterials, 2011-10, Vol.32 (30), p.7600-7608

2011

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Outcomes of Kidney Transplantation in HIV-Infected Recipients

The New England journal of medicine, 2010-11, Vol.363 (21), p.2004-2014

2010

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Positive allosteric modulators (PAMs) of the group II metabotropic glutamate receptors: Design, synthesis, and evaluation as ex-vivo tool compounds

Bioorganic & medicinal chemistry letters, 2021-10, Vol.50, p.128342-128342, Article 128342

2021

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Discovery of VU0467485/AZ13713945: An M4 PAM Evaluated as a Preclinical Candidate for the Treatment of Schizophrenia

ACS medicinal chemistry letters, 2017-02, Vol.8 (2), p.233-238

2017

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Lead optimization of the VU0486321 series of mGlu1 PAMs. Part 4: SAR reveals positive cooperativity across multiple mGlu receptor subtypes leading to subtype unselective PAMs

Bioorganic & medicinal chemistry letters, 2021-01, Vol.32, p.127724-127724, Article 127724

2021

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Lead optimization of the VU0486321 series of mGlu 1 PAMs. Part 4: SAR reveals positive cooperativity across multiple mGlu receptor subtypes leading to subtype unselective PAMs

Bioorganic & medicinal chemistry letters, 2021-01, Vol.32, p.127724

2021

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Novel M4 positive allosteric modulators derived from questioning the role and impact of a presumed intramolecular hydrogen-bonding motif in β-amino carboxamide-harboring ligands

Bioorganic & medicinal chemistry letters, 2019-02, Vol.29 (3), p.362-366

2019

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The Herpes Simplex Virus Type 1 UL20 Protein Modulates Membrane Fusion Events during Cytoplasmic Virion Morphogenesis and Virus-Induced Cell Fusion

UL20 Protein Functions Precede and Are Required for the UL11 Functions of Herpes Simplex Virus Type 1 Cytoplasmic Virion Envelopment

Genetic analysis of the SARS-coronavirus spike glycoprotein functional domains involved in cell-surface expression and cell-to-cell fusion

Herpes Simplex Virus Type 1 Glycoprotein K and the UL20 Protein Are Interdependent for Intracellular Trafficking and trans-Golgi Network Localization

Herpes Simplex Virus Type 1 gK Is Required for gB-Mediated Virus-Induced Cell Fusion, While neither gB and gK nor gB and UL20p Function Redundantly in Virion De-Envelopment

Genetic Analysis of the Herpes Simplex Virus Type 1 UL20 Protein Domains Involved in Cytoplasmic Virion Envelopment and Virus-Induced Cell Fusion

The herpes simplex virus UL20 protein functions in glycoprotein K (gK) intracellular transport and virus-induced cell fusion are independent of UL20 functions in cytoplasmic virion envelopment

Management of Pilomatrix Carcinoma: A Case Report of Successful Treatment with Mohs Micrographic Surgery and Review of the Literature

Facial Port-Wine Stain: When to Worry?

Effective treatment of human breast tumor in a mouse xenograft model with herpes simplex virus type 1 specifying the NV1020 genomic deletion and the gBsyn3 syncytial mutation enabling high viral replication and spread in breast cancer cells

Clinical case of the month. A 48-year-old man with right lower extremity weakness and pain

Genetics and functions of herpes simplex virus type 1 membrane proteins in virus-induced cell fusion, virion morphogenesis and egress

Allosteric Modulation of Seven Transmembrane Spanning Receptors: Theory, Practice, and Opportunities for Central Nervous System Drug Discovery

Antipsychotic Drug-Like Effects of the Selective M4 Muscarinic Acetylcholine Receptor Positive Allosteric Modulator VU0152100

Integrated nanotechnology platform for tumor-targeted multimodal imaging and therapeutic cargo release

mGlu1-mediated restoration of prefrontal cortex inhibitory signaling reverses social and cognitive deficits in an NMDA hypofunction model in mice

Selective Activation of M4 Muscarinic Acetylcholine Receptors Reverses MK-801-Induced Behavioral Impairments and Enhances Associative Learning in Rodents

Challenges in the development of an M 4 PAM in vivo tool compound: The discovery of VU0467154 and unexpected DMPK profiles of close analogs

Targeted multifunctional gold-based nanoshells for magnetic resonance-guided laser ablation of head and neck cancer

Outcomes of Kidney Transplantation in HIV-Infected Recipients

Positive allosteric modulators (PAMs) of the group II metabotropic glutamate receptors: Design, synthesis, and evaluation as ex-vivo tool compounds

Discovery of VU0467485/AZ13713945: An M4 PAM Evaluated as a Preclinical Candidate for the Treatment of Schizophrenia

Lead optimization of the VU0486321 series of mGlu1 PAMs. Part 4: SAR reveals positive cooperativity across multiple mGlu receptor subtypes leading to subtype unselective PAMs

Lead optimization of the VU0486321 series of mGlu 1 PAMs. Part 4: SAR reveals positive cooperativity across multiple mGlu receptor subtypes leading to subtype unselective PAMs

Novel M4 positive allosteric modulators derived from questioning the role and impact of a presumed intramolecular hydrogen-bonding motif in β-amino carboxamide-harboring ligands

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