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The c-Myc/miR17-92/PTEN Axis Tunes PI3K Activity to Control Expression of Recombination Activating Genes in Early B Cell Development

Frontiers in immunology, 2018-11, Vol.9, p.2715-2715

2018

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B-cell depletion reactivates B lymphopoiesis in the BM and rejuvenates the B lineage in aging

Blood, 2011-03, Vol.117 (11), p.3104-3112

2011

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miR-29 Sustains B Cell Survival and Controls Terminal Differentiation via Regulation of PI3K Signaling

Cell reports (Cambridge), 2020-12, Vol.33 (9), p.108436-108436, Article 108436

2020

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A c-Myc/miR17-92/Pten Axis Controls PI3K-Mediated Positive and Negative Selection in B Cell Development and Reconstitutes CD19 Deficiency

Cell reports (Cambridge), 2016-07, Vol.16 (2), p.419-431

2016

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Aging and neoteny in the B lineage

Blood, 2012-11, Vol.120 (20), p.4143-4149

2012

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TOLL-like receptor ligands stimulate aberrant class switch recombination in early B cell precursors

International immunology, 2008-12, Vol.20 (12), p.1575-1585

2008

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Alginate encapsulated cells secreting Fas‐ligand reduce lymphoma carcinogenicity

Cancer science, 2012-01, Vol.103 (1), p.116-124

2012

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CpG DNA stimulates autoreactive immature B cells in the bone marrow

European Journal of Immunology, 2007-06, Vol.37 (6), p.1463-1475

2007

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Self-Antigen does not Accelerate Immature B Cell Apoptosis, but Stimulates Receptor Editing as a Consequence of Developmental Arrest

Proceedings of the National Academy of Sciences - PNAS, 1997-08, Vol.94 (17), p.9267-9272

1997

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miR-17∼92 in lymphocyte development and lymphomagenesis

Cancer letters, 2019-04, Vol.446, p.73-80

2019

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Human CD19(+)CD25(high) B regulatory cells suppress proliferation of CD4(+) T cells and enhance Foxp3 and CTLA-4 expression in T-regulatory cells

Autoimmunity reviews, 2012-07, Vol.11 (9), p.670

2012

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Developmental Regulation of B Lymphocyte Immune Tolerance Compartmentalizes Clonal Selection from Receptor Selection

Cell, 1998-01, Vol.92 (2), p.173-182

1998

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Modulation of matrix metalloproteinase-9 (MMP-9) secretion in B lymphopoiesis

International immunology, 2006-09, Vol.18 (9), p.1355-1362

2006

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Depletion of B lymphocytes in rheumatoid arthritis patients modifies IL-8-anti-IL-8 autoantibody network

Clinical immunology (Orlando, Fla.), 2009-10, Vol.133 (1), p.108-116

2009

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Spontaneous Class Switch Recombination in B Cell Lymphopoiesis Generates Aberrant Switch Junctions and Is Increased after VDJ Rearrangement

The Journal of immunology (1950), 2007-11, Vol.179 (10), p.6555-6560

2007

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Rheumatoid arthritis patients treated with Janus kinase inhibitors show reduced humoral immune responses following BNT162b2 vaccination

Rheumatology (Oxford, England), 2022-08, Vol.61 (8), p.3439-3447

2022

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Homeostatic regulation of aging and rejuvenation in the B lineage cells

Critical reviews in immunology, 2013, Vol.33 (1), p.41

Melamed, Doron

2013

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Modification of Ligand-independent B Cell Receptor Tonic Signals Activates Receptor Editing in Immature B Lymphocytes

The Journal of biological chemistry, 2004-04, Vol.279 (14), p.13418-13424

2004

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Reversing B cell aging

Aging (Albany, NY.), 2011-04, Vol.3 (4), p.438-443

2011

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Peripheral B cells repress B-cell regeneration in aging through a TNF-α/IGFBP-1/IGF-1 immune-endocrine axis

Blood, 2021-11, Vol.138 (19), p.1817-1829

2021

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Laquinimod modulates B cells and their regulatory effects on T cells in Multiple Sclerosis

Journal of neuroimmunology, 2012-10, Vol.251 (1), p.45-54

2012

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Aging affects B‐cell antigen receptor repertoire diversity in primary and secondary lymphoid tissues

European journal of immunology, 2016-02, Vol.46 (2), p.480-492

2016

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Rituximab-induced direct inhibition of T-cell activation

Cancer Immunology, Immunotherapy, 2012-08, Vol.61 (8), p.1233-1241

2012

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Depletion of B cells rejuvenates the peripheral B‐cell compartment but is insufficient to restore immune competence in aging

Aging cell, 2019-08, Vol.18 (4), p.e12959-n/a

2019

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The c-Myc/miR17-92/PTEN Axis Tunes PI3K Activity to Control Expression of Recombination Activating Genes in Early B Cell Development

B-cell depletion reactivates B lymphopoiesis in the BM and rejuvenates the B lineage in aging

miR-29 Sustains B Cell Survival and Controls Terminal Differentiation via Regulation of PI3K Signaling

A c-Myc/miR17-92/Pten Axis Controls PI3K-Mediated Positive and Negative Selection in B Cell Development and Reconstitutes CD19 Deficiency

Aging and neoteny in the B lineage

TOLL-like receptor ligands stimulate aberrant class switch recombination in early B cell precursors

Alginate encapsulated cells secreting Fas‐ligand reduce lymphoma carcinogenicity

CpG DNA stimulates autoreactive immature B cells in the bone marrow

Self-Antigen does not Accelerate Immature B Cell Apoptosis, but Stimulates Receptor Editing as a Consequence of Developmental Arrest

miR-17∼92 in lymphocyte development and lymphomagenesis

Human CD19(+)CD25(high) B regulatory cells suppress proliferation of CD4(+) T cells and enhance Foxp3 and CTLA-4 expression in T-regulatory cells

Developmental Regulation of B Lymphocyte Immune Tolerance Compartmentalizes Clonal Selection from Receptor Selection

Modulation of matrix metalloproteinase-9 (MMP-9) secretion in B lymphopoiesis

Depletion of B lymphocytes in rheumatoid arthritis patients modifies IL-8-anti-IL-8 autoantibody network

Spontaneous Class Switch Recombination in B Cell Lymphopoiesis Generates Aberrant Switch Junctions and Is Increased after VDJ Rearrangement

Rheumatoid arthritis patients treated with Janus kinase inhibitors show reduced humoral immune responses following BNT162b2 vaccination

Homeostatic regulation of aging and rejuvenation in the B lineage cells

Modification of Ligand-independent B Cell Receptor Tonic Signals Activates Receptor Editing in Immature B Lymphocytes

Reversing B cell aging

Peripheral B cells repress B-cell regeneration in aging through a TNF-α/IGFBP-1/IGF-1 immune-endocrine axis

Deleterious Mutations in LRBA Are Associated with a Syndrome of Immune Deficiency and Autoimmunity

Laquinimod modulates B cells and their regulatory effects on T cells in Multiple Sclerosis

Aging affects B‐cell antigen receptor repertoire diversity in primary and secondary lymphoid tissues

Rituximab-induced direct inhibition of T-cell activation

Depletion of B cells rejuvenates the peripheral B‐cell compartment but is insufficient to restore immune competence in aging

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