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NADPH oxidases and cancer

Clinical science (1979), 2015-06, Vol.128 (12), p.863-875

2015

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Molecular mechanisms underlying chronic inflammation-associated cancers

Cancer letters, 2014-04, Vol.345 (2), p.164-173

2014

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Purification and Characterization of DUOX Peroxidase Homology Domains (PHDs)

Methods in molecular biology (Clifton, N.J.), 2019, Vol.1982, p.61

Meitzler, Jennifer L

2019

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NADPH oxidases: a perspective on reactive oxygen species production in tumor biology

Antioxidants & redox signaling, 2014-06, Vol.20 (17), p.2873-2889

2014

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NADPH oxidase 1 is highly expressed in human large and small bowel cancers

PloS one, 2020-05, Vol.15 (5), p.e0233208

2020

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NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction

The Journal of biological chemistry, 2017-05, Vol.292 (19), p.7866-7887

2017

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Hydrogen peroxide-producing NADPH oxidases and the promotion of migratory phenotypes in cancer

Archives of biochemistry and biophysics, 2019-10, Vol.675, p.108076-108076, Article 108076

2019

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Exogenous DNA enhances DUOX2 expression and function in human pancreatic cancer cells by activating the cGAS-STING signaling pathway

Free radical biology & medicine, 2023-08, Vol.205, p.262-274

2023

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Guidelines for the Detection of NADPH Oxidases by Immunoblot and RT-qPCR

Methods in molecular biology (Clifton, N.J.), 2019, Vol.1982, p.191

2019

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Interleukin-4 and interleukin-13 increase NADPH oxidase 1-related proliferation of human colon cancer cells

Oncotarget, 2017-06, Vol.8 (24), p.38113-38135

2017

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IL-4 and IL-17A Cooperatively Promote Hydrogen Peroxide Production, Oxidative DNA Damage, and Upregulation of Dual Oxidase 2 in Human Colon and Pancreatic Cancer Cells

The Journal of immunology (1950), 2019-11, Vol.203 (9), p.2532-2544

2019

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Characterization of potent and selective iodonium-class inhibitors of NADPH oxidases

Biochemical pharmacology, 2017-11, Vol.143, p.25-38

2017

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Decoding NADPH oxidase 4 expression in human tumors

Redox biology, 2017-10, Vol.13 (C), p.182-195

2017

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Activation of TLR4 is required for the synergistic induction of dual oxidase 2 and dual oxidase A2 by IFN-γ and lipopolysaccharide in human pancreatic cancer cell lines

The Journal of immunology (1950), 2013-02, Vol.190 (4), p.1859-1872

2013

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Conserved Cysteine Residues Provide a Protein-Protein Interaction Surface in Dual Oxidase (DUOX) Proteins

The Journal of biological chemistry, 2013-03, Vol.288 (10), p.7147-7157

2013

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The soluble domains of Gpi8 and Gaa1, two subunits of glycosylphosphatidylinositol transamidase (GPI-T), assemble into a complex

Archives of biochemistry and biophysics, 2017-11, Vol.633, p.58-67

2017

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Caenorhabditis elegans and human dual oxidase 1 (DUOX1) "peroxidase" domains: insights into heme binding and catalytic activity

The Journal of biological chemistry, 2009-07, Vol.284 (28), p.18634-18643

2009

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Characterization of NADPH oxidase 5 expression in human tumors and tumor cell lines with a novel mouse monoclonal antibody

Free radical biology & medicine, 2013-12, Vol.65, p.497-508

2013

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Abstract 1456: Dexamethasone suppresses cytokine-induced dual oxidase 2 (Duox2) and VEGF-A expression in human pancreatic cancer cells in vitro and pancreatic cancer growth in xenografts

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.1456-1456

2016

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Structural stability and heme binding potential of the truncated human dual oxidase 2 (DUOX2) peroxidase domain

Archives of biochemistry and biophysics, 2011-08, Vol.512 (2), p.197-203

2011

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Functional activity and tumor-specific expression of dual oxidase 2 in pancreatic cancer cells and human malignancies characterized with a novel monoclonal antibody

International journal of oncology, 2013-04, Vol.42 (4), p.1229-1238

2013

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Perturbed Heme Binding Is Responsible for the Blistering Phenotype Associated with Mutations in the Caenorhabditis elegans Dual Oxidase 1 (DUOX1) Peroxidase Domain

The Journal of biological chemistry, 2010-12, Vol.285 (52), p.40991-41000

2010

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NADPH oxidase 5 (NOX5)-induced reactive oxygen signaling modulates normoxic HIF-1α and p27 Kip1 expression in malignant melanoma and other human tumors

Molecular carcinogenesis, 2017-12, Vol.56 (12), p.2643-2662

2017

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NADPH oxidase 5 (NOX5)—induced reactive oxygen signaling modulates normoxic HIF‐1α and p27Kip1 expression in malignant melanoma and other human tumors

Molecular carcinogenesis, 2017-12, Vol.56 (12), p.2643-2662

2017

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Dual oxidase 2 and pancreatic adenocarcinoma: IFN-γ-mediated dual oxidase 2 overexpression results in H2O2-induced, ERK-associated up-regulation of HIF-1α and VEGF-A

Oncotarget, 2016-10, Vol.7 (42), p.68412-68433

2016

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NADPH oxidases and cancer

Molecular mechanisms underlying chronic inflammation-associated cancers

Purification and Characterization of DUOX Peroxidase Homology Domains (PHDs)

NADPH oxidases: a perspective on reactive oxygen species production in tumor biology

NADPH oxidase 1 is highly expressed in human large and small bowel cancers

NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction

Hydrogen peroxide-producing NADPH oxidases and the promotion of migratory phenotypes in cancer

Exogenous DNA enhances DUOX2 expression and function in human pancreatic cancer cells by activating the cGAS-STING signaling pathway

Guidelines for the Detection of NADPH Oxidases by Immunoblot and RT-qPCR

Interleukin-4 and interleukin-13 increase NADPH oxidase 1-related proliferation of human colon cancer cells

IL-4 and IL-17A Cooperatively Promote Hydrogen Peroxide Production, Oxidative DNA Damage, and Upregulation of Dual Oxidase 2 in Human Colon and Pancreatic Cancer Cells

Characterization of potent and selective iodonium-class inhibitors of NADPH oxidases

Decoding NADPH oxidase 4 expression in human tumors

Activation of TLR4 is required for the synergistic induction of dual oxidase 2 and dual oxidase A2 by IFN-γ and lipopolysaccharide in human pancreatic cancer cell lines

Conserved Cysteine Residues Provide a Protein-Protein Interaction Surface in Dual Oxidase (DUOX) Proteins

The soluble domains of Gpi8 and Gaa1, two subunits of glycosylphosphatidylinositol transamidase (GPI-T), assemble into a complex

Caenorhabditis elegans and human dual oxidase 1 (DUOX1) "peroxidase" domains: insights into heme binding and catalytic activity

Characterization of NADPH oxidase 5 expression in human tumors and tumor cell lines with a novel mouse monoclonal antibody

Abstract 1456: Dexamethasone suppresses cytokine-induced dual oxidase 2 (Duox2) and VEGF-A expression in human pancreatic cancer cells in vitro and pancreatic cancer growth in xenografts

Structural stability and heme binding potential of the truncated human dual oxidase 2 (DUOX2) peroxidase domain

Functional activity and tumor-specific expression of dual oxidase 2 in pancreatic cancer cells and human malignancies characterized with a novel monoclonal antibody

Perturbed Heme Binding Is Responsible for the Blistering Phenotype Associated with Mutations in the Caenorhabditis elegans Dual Oxidase 1 (DUOX1) Peroxidase Domain

NADPH oxidase 5 (NOX5)-induced reactive oxygen signaling modulates normoxic HIF-1α and p27 Kip1 expression in malignant melanoma and other human tumors

NADPH oxidase 5 (NOX5)—induced reactive oxygen signaling modulates normoxic HIF‐1α and p27Kip1 expression in malignant melanoma and other human tumors

Dual oxidase 2 and pancreatic adenocarcinoma: IFN-γ-mediated dual oxidase 2 overexpression results in H2O2-induced, ERK-associated up-regulation of HIF-1α and VEGF-A

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