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Intestinal Sulfation Is Essential to Protect Against Colitis and Colonic Carcinogenesis

Gastroenterology (New York, N.Y. 1943), 2021-07, Vol.161 (1), p.271-286.e11

2021

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PXR Ablation Alleviates Diet-Induced and Genetic Obesity and Insulin Resistance in Mice

Diabetes (New York, N.Y.), 2013-06, Vol.62 (6), p.1876-1887

2013

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Activation of aryl hydrocarbon receptor dissociates fatty liver from insulin resistance by inducing fibroblast growth factor 21

Hepatology (Baltimore, Md.), 2015-06, Vol.61 (6), p.1908-1919

2015

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Constitutive Activation of the Human Aryl Hydrocarbon Receptor in Mice Promotes Hepatocarcinogenesis Independent of Its Coactivator Gadd45b

Toxicological sciences, 2019-02, Vol.167 (2), p.581-592

2019

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Altenusin, a Nonsteroidal Microbial Metabolite, Attenuates Nonalcoholic Fatty Liver Disease by Activating the Farnesoid X Receptor

Molecular pharmacology, 2017-10, Vol.92 (4), p.425-436

2017

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Gadd45b is required in part for the anti-obesity effect of constitutive androstane receptor (CAR)

Acta pharmaceutica Sinica. B, 2021-02, Vol.11 (2), p.434-441

2021

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Activation of the Aryl Hydrocarbon Receptor Sensitizes Mice to Nonalcoholic Steatohepatitis by Deactivating Mitochondrial Sirtuin Deacetylase Sirt3

Molecular and Cellular Biology, 2013-05, Vol.33 (10), p.2047-2055

2013

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Hepatic Overexpression of CD36 Improves Glycogen Homeostasis and Attenuates High-Fat Diet-Induced Hepatic Steatosis and Insulin Resistance

Molecular and cellular biology, 2016-11, Vol.36 (21), p.2715-2727

2016

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Cholesterol Sulfate and Cholesterol Sulfotransferase Inhibit Gluconeogenesis by Targeting Hepatocyte Nuclear Factor 4α

Molecular and Cellular Biology, 2014-02, Vol.34 (3), p.485-497

2014

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Phenobarbital Induces SLC13A5 Expression through Activation of PXR but Not CAR in Human Primary Hepatocytes

Cells (Basel, Switzerland), 2021-12, Vol.10 (12), p.3381

2021

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Sex-Specific Effect of Estrogen Sulfotransferase on Mouse Models of Type 2 Diabetes

Diabetes (New York, N.Y.), 2012-06, Vol.61 (6), p.1543-1551

2012

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Sulfation of chondroitin and bile acids converges to antagonize Wnt/β-catenin signaling and inhibit APC deficiency-induced gut tumorigenesis

Acta pharmaceutica Sinica. B, 2024-03, Vol.14 (3), p.1241-1256

2024

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Chronic Activation of FXR in Transgenic Mice Caused Perinatal Toxicity and Sensitized Mice to Cholesterol Toxicity

Molecular endocrinology (Baltimore, Md.), 2015-04, Vol.29 (4), p.571-582

2015

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Chronic Activation of LXRα Sensitizes Mice to Hepatocellular Carcinoma

Hepatology communications, 2022-05, Vol.6 (5), p.1123-1139

2022

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Pregnane X Receptor as a Therapeutic Target to Inhibit Androgen Activity

Endocrinology (Philadelphia), 2010-12, Vol.151 (12), p.5721-5729

2010

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Activation of Liver X Receptor α Sensitizes Mice to T‐Cell Mediated Hepatitis

Hepatology communications, 2020-11, Vol.4 (11), p.1664-1679

2020

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Transgenic overexpression of steroid sulfatase alleviates cholestasis

Liver research, 2017-06, Vol.1 (1), p.63-69

2017

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ERINA Is an Estrogen-Responsive LncRNA That Drives Breast Cancer through the E2F1/RB1 Pathway

Cancer research (Chicago, Ill.), 2020-10, Vol.80 (20), p.4399-4413

2020

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CAR Suppresses Hepatic Gluconeogenesis by Facilitating the Ubiquitination and Degradation of PGC1α

Molecular endocrinology (Baltimore, Md.), 2015-11, Vol.29 (11), p.1558-1570

2015

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Phenobarbital induces SLC13A5 expression through activation of PXR but not CAR in human primary hepatocytes

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Aryl Hydrocarbon Receptor Signaling Prevents Activation of Hepatic Stellate Cells and Liver Fibrogenesis in Mice

Gastroenterology (New York, N.Y. 1943), 2019-09, Vol.157 (3), p.793-806.e14

2019

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PXR Prevents Cholesterol Gallstone Disease by Regulating Biosynthesis and Transport of Bile Salts

Gastroenterology (New York, N.Y. 1943), 2011-06, Vol.140 (7), p.2095-2106

2011

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The de-sulfinylation enzyme sulfiredoxin-1 attenuates hepatic stellate cell activation and liver fibrosis by modulating the PTPN12-NLRP3 axis

Hepatology (Baltimore, Md.), 2024-10

2024

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PAPSS2 ablation prevents acetaminophen‐induced hepatotoxicity in mice

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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Activation of Pregnane X Receptor Sensitizes Mice to Hemorrhagic Shock–Induced Liver Injury

Hepatology (Baltimore, Md.), 2019-09, Vol.70 (3), p.995-1010

2019

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Intestinal Sulfation Is Essential to Protect Against Colitis and Colonic Carcinogenesis

PXR Ablation Alleviates Diet-Induced and Genetic Obesity and Insulin Resistance in Mice

Activation of aryl hydrocarbon receptor dissociates fatty liver from insulin resistance by inducing fibroblast growth factor 21

Constitutive Activation of the Human Aryl Hydrocarbon Receptor in Mice Promotes Hepatocarcinogenesis Independent of Its Coactivator Gadd45b

Altenusin, a Nonsteroidal Microbial Metabolite, Attenuates Nonalcoholic Fatty Liver Disease by Activating the Farnesoid X Receptor

Gadd45b is required in part for the anti-obesity effect of constitutive androstane receptor (CAR)

Activation of the Aryl Hydrocarbon Receptor Sensitizes Mice to Nonalcoholic Steatohepatitis by Deactivating Mitochondrial Sirtuin Deacetylase Sirt3

Hepatic Overexpression of CD36 Improves Glycogen Homeostasis and Attenuates High-Fat Diet-Induced Hepatic Steatosis and Insulin Resistance

Cholesterol Sulfate and Cholesterol Sulfotransferase Inhibit Gluconeogenesis by Targeting Hepatocyte Nuclear Factor 4α

Phenobarbital Induces SLC13A5 Expression through Activation of PXR but Not CAR in Human Primary Hepatocytes

Sex-Specific Effect of Estrogen Sulfotransferase on Mouse Models of Type 2 Diabetes

Sulfation of chondroitin and bile acids converges to antagonize Wnt/β-catenin signaling and inhibit APC deficiency-induced gut tumorigenesis

Chronic Activation of FXR in Transgenic Mice Caused Perinatal Toxicity and Sensitized Mice to Cholesterol Toxicity

Chronic Activation of LXRα Sensitizes Mice to Hepatocellular Carcinoma

Pregnane X Receptor as a Therapeutic Target to Inhibit Androgen Activity

Activation of Liver X Receptor α Sensitizes Mice to T‐Cell Mediated Hepatitis

Transgenic overexpression of steroid sulfatase alleviates cholestasis

ERINA Is an Estrogen-Responsive LncRNA That Drives Breast Cancer through the E2F1/RB1 Pathway

CAR Suppresses Hepatic Gluconeogenesis by Facilitating the Ubiquitination and Degradation of PGC1α

Phenobarbital induces SLC13A5 expression through activation of PXR but not CAR in human primary hepatocytes

Aryl Hydrocarbon Receptor Signaling Prevents Activation of Hepatic Stellate Cells and Liver Fibrogenesis in Mice

PXR Prevents Cholesterol Gallstone Disease by Regulating Biosynthesis and Transport of Bile Salts

The de-sulfinylation enzyme sulfiredoxin-1 attenuates hepatic stellate cell activation and liver fibrosis by modulating the PTPN12-NLRP3 axis

PAPSS2 ablation prevents acetaminophen‐induced hepatotoxicity in mice

Activation of Pregnane X Receptor Sensitizes Mice to Hemorrhagic Shock–Induced Liver Injury

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