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Modeling conformational states of proteins with AlphaFold

Current opinion in structural biology, 2023-08, Vol.81, p.102645-102645, Article 102645

2023

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Targeting in silico GPCR conformations with ultra-large library screening for hit discovery

Trends in pharmacological sciences (Regular ed.), 2023-03, Vol.44 (3), p.150-161

2023

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Cisplatin and 5-fluorouracil with or without epidermal growth factor receptor inhibition panitumumab for patients with non-resectable, advanced or metastatic oesophageal squamous cell cancer: a prospective, open-label, randomised phase III AIO/EORTC trial (POWER)

Annals of oncology, 2020-02, Vol.31 (2), p.228-235

2020

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Millifluidic magnetophoresis-based chip for age-specific fractionation: evaluating the impact of age on metabolomics and gene expression in yeast

Lab on a chip, 2024-05, Vol.24 (11), p.2987-2998

2024

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Tracing the evolution of the heterotrimeric G protein α subunit in Metazoa

BMC evolutionary biology, 2018-04, Vol.18 (1), p.51

2018

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Model-Free Approach to the Dynamic Interpretation of Residual Dipolar Couplings in Globular Proteins

Journal of the American Chemical Society, 2001-06, Vol.123 (25), p.6098-6107

2001

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Palbociclib in combination with letrozole as first or later line therapy for patients with locally advanced, inoperable or metastatic HR+/HER2- breast cancer in Germany: Interim results of the INGE-B phase II study

Annals of oncology, 2018-10, Vol.29, p.viii111-viii111

2018

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Cisplatin/5-fluorouracil +/- panitumumab for patients with non-resectable, advanced or metastatic esophageal squamous cell cancer: A randomized phase III AIO/EORTC trial with an extensive biomarker program

Annals of oncology, 2018-06, Vol.29, p.v103-v103

2018

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Antikörper zur adoptiven Immuntherapie solider Tumoren

Der Onkologe, 2012-09, Vol.18 (9), p.757-769

2012

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The benefit of negative pressure dressings in vascular surgery patients with infrainguinal incisions

Journal of vascular surgery, 2021-11, Vol.74 (5), p.1668-1672

2021

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PROSHIFT: protein chemical shift prediction using artificial neural networks

Journal of biomolecular NMR, 2003-05, Vol.26 (1), p.25-37

Meiler, Jens

2003

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36LBA Pathological response to neoadjuvant 5-FU, oxaliplatin and docetaxel (FLOT) versus epirubicin, cisplatin and 5-FU (ECF) in patients with locally advanced, resectable gastric/esophagogastric junction (EGJ) cancer: Data from the phase II part of the FLOT4 phase III study of the AIO

European journal of cancer (1990), 2015-09, Vol.51, p.S728-S728

2015

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Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma

The New England journal of medicine, 2015-11, Vol.373 (19), p.1803-1813

2015

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648 Distinct proteostasis and structural states drive VX-809 susceptibility of cystic fibrosis transmembrane conductance regulator mutants

Journal of cystic fibrosis, 2022-10, Vol.21, p.S355-S356

2022

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DipoCoup: A versatile program for 3D-structure homology comparison based on residual dipolar couplings and pseudocontact shifts

Journal of biomolecular NMR, 2000-08, Vol.17 (4), p.283-294

2000

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Coupled Prediction of Protein Secondary and Tertiary Structure

Proceedings of the National Academy of Sciences - PNAS, 2003-10, Vol.100 (21), p.12105-12110

2003

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1890P Switch-maintenance therapy with nivolumab in TKI-sensitive patients with metastatic renal cell carcinoma (mRCC): Subgroup analysis for PD-L1 status of a randomized phase II study (NIVOSWITCH)

Annals of oncology, 2023-10, Vol.34, p.S1017-S1017

2023

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Rapid Protein Fold Determination Using Unassigned NMR Data

Proceedings of the National Academy of Sciences - PNAS, 2003-12, Vol.100 (26), p.15404-15409

2003

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Assessment and challenges of ligand docking into comparative models of G-protein coupled receptors

PloS one, 2013-07, Vol.8 (7), p.e67302

2013

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Tip60 Is a Cell-Type-Specific Transcriptional Regulator

Journal of biochemistry (Tokyo), 2001-04, Vol.129 (4), p.635-641

2001

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679P Final results on efficacy and patient reported outcomes (PRO) of a randomized phase II trial investigating nivolumab switch-maintenance after TKI induction in metastatic clear cell renal cell carcinoma (mRCC) patients (NIVOSWITCH)

Annals of oncology, 2021-09, Vol.32, p.S700-S700

2021

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Model-Free Analysis of Protein Backbone Motion from Residual Dipolar Couplings

Journal of the American Chemical Society, 2002-05, Vol.124 (20), p.5822-5833

2002

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The INPHARMA Method: Protein-Mediated Interligand NOEs for Pharmacophore Mapping

Angewandte Chemie (International ed.), 2005-07, Vol.44 (27), p.4172-4175

2005

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Determination of Aliphatic Side-Chain Conformation Using Cross-Correlated Relaxation: Application to an Extraordinarily Stable 2‘-aminoethoxy-Modified Oligonucleotide Triplex

Journal of the American Chemical Society, 2001-08, Vol.123 (30), p.7364-7370

2001

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Modeling conformational states of proteins with AlphaFold

Targeting in silico GPCR conformations with ultra-large library screening for hit discovery

Cisplatin and 5-fluorouracil with or without epidermal growth factor receptor inhibition panitumumab for patients with non-resectable, advanced or metastatic oesophageal squamous cell cancer: a prospective, open-label, randomised phase III AIO/EORTC trial (POWER)

Millifluidic magnetophoresis-based chip for age-specific fractionation: evaluating the impact of age on metabolomics and gene expression in yeast

Tracing the evolution of the heterotrimeric G protein α subunit in Metazoa

Model-Free Approach to the Dynamic Interpretation of Residual Dipolar Couplings in Globular Proteins

Palbociclib in combination with letrozole as first or later line therapy for patients with locally advanced, inoperable or metastatic HR+/HER2- breast cancer in Germany: Interim results of the INGE-B phase II study

Cisplatin/5-fluorouracil +/- panitumumab for patients with non-resectable, advanced or metastatic esophageal squamous cell cancer: A randomized phase III AIO/EORTC trial with an extensive biomarker program

Antikörper zur adoptiven Immuntherapie solider Tumoren

The benefit of negative pressure dressings in vascular surgery patients with infrainguinal incisions

PROSHIFT: protein chemical shift prediction using artificial neural networks

36LBA Pathological response to neoadjuvant 5-FU, oxaliplatin and docetaxel (FLOT) versus epirubicin, cisplatin and 5-FU (ECF) in patients with locally advanced, resectable gastric/esophagogastric junction (EGJ) cancer: Data from the phase II part of the FLOT4 phase III study of the AIO

Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma

648 Distinct proteostasis and structural states drive VX-809 susceptibility of cystic fibrosis transmembrane conductance regulator mutants

DipoCoup: A versatile program for 3D-structure homology comparison based on residual dipolar couplings and pseudocontact shifts

Coupled Prediction of Protein Secondary and Tertiary Structure

1890P Switch-maintenance therapy with nivolumab in TKI-sensitive patients with metastatic renal cell carcinoma (mRCC): Subgroup analysis for PD-L1 status of a randomized phase II study (NIVOSWITCH)

Rapid Protein Fold Determination Using Unassigned NMR Data

Assessment and challenges of ligand docking into comparative models of G-protein coupled receptors

Tip60 Is a Cell-Type-Specific Transcriptional Regulator

First-line therapy with fludarabine compared with chlorambucil does not result in a major benefit for elderly patients with advanced chronic lymphocytic leukemia

679P Final results on efficacy and patient reported outcomes (PRO) of a randomized phase II trial investigating nivolumab switch-maintenance after TKI induction in metastatic clear cell renal cell carcinoma (mRCC) patients (NIVOSWITCH)

Model-Free Analysis of Protein Backbone Motion from Residual Dipolar Couplings

The INPHARMA Method: Protein-Mediated Interligand NOEs for Pharmacophore Mapping

Determination of Aliphatic Side-Chain Conformation Using Cross-Correlated Relaxation: Application to an Extraordinarily Stable 2‘-aminoethoxy-Modified Oligonucleotide Triplex

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