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Inflammation in the Pathophysiology and Therapy of Cardiometabolic Disease

Endocrine reviews, 2019-08, Vol.40 (4), p.1080-1091

2019

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Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells

Nature medicine, 2011-11, Vol.17 (11), p.1481-1489

2011

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Cystine/Glutamate antiporter system xc- deficiency impairs macrophage glutathione metabolism and cytokine production

PloS one, 2023-10, Vol.18 (10), p.e0291950-e0291950

2023

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Islet amyloid formation is an important determinant for inducing islet inflammation in high-fat-fed human IAPP transgenic mice

Diabetologia, 2014-09, Vol.57 (9), p.1884-1888

2014

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Pancreatic α Cell-Derived Glucagon-Related Peptides Are Required for β Cell Adaptation and Glucose Homeostasis

Cell reports (Cambridge), 2017-03, Vol.18 (13), p.3192-3203

2017

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Free Fatty Acids Induce a Proinflammatory Response in Islets via the Abundantly Expressed Interleukin-1 Receptor I

Endocrinology (Philadelphia), 2009-12, Vol.150 (12), p.5218-5229

2009

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Prohormone convertase 1/3 deficiency causes obesity due to impaired proinsulin processing

Nature communications, 2022-08, Vol.13 (1), p.4761-4761, Article 4761

2022

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IL-1β promotes adipogenesis by directly targeting adipocyte precursors

Nature communications, 2024-09, Vol.15 (1), p.7957-18, Article 7957

2024

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β Cell-Specific Deletion of the IL-1 Receptor Antagonist Impairs β Cell Proliferation and Insulin Secretion

Cell reports (Cambridge), 2018-02, Vol.22 (7), p.1774-1786

2018

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Inflammation in obesity, diabetes, and related disorders

Immunity (Cambridge, Mass.), 2022-01, Vol.55 (1), p.31-55

2022

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Diesel Exhaust Particle (DEP)-induced glucose intolerance is driven by an intestinal innate immune response and NLRP3 activation in mice

Particle and fibre toxicology, 2023-07, Vol.20 (1), p.25-25, Article 25

2023

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Lung versus gut exposure to air pollution particles differentially affect metabolic health in mice

Particle and fibre toxicology, 2023-03, Vol.20 (1), p.7-7, Article 7

2023

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Islet inflammation in type 2 diabetes

Seminars in immunopathology, 2019-07, Vol.41 (4), p.501-513

2019

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Protocol for isolation and spectral flow cytometry analysis of immune cells from the murine exocrine and endocrine pancreas

STAR protocols, 2023-12, Vol.4 (4), p.102664, Article 102664

2023

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IL-1beta promotes the age-associated decline of beta cell function

iScience, 2021-11, Vol.24 (11), p.103250-103250, Article 103250

2021

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Targeting colonic macrophages improves glycemic control in high-fat diet-induced obesity

Communications biology, 2022-04, Vol.5 (1), p.370-370, Article 370

2022

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Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation

Nature immunology, 2017-03, Vol.18 (3), p.283-292

2017

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Cystine/glutamate antiporter System xc- deficiency impairs insulin secretion in mice

Diabetologia, 2023-11, Vol.66 (11), p.2062-2074

2023

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Similar metabolic pathways are affected in both Congenital Myasthenic Syndrome-22 and Prader-Willi Syndrome

Biochimica et biophysica acta. Molecular basis of disease, 2024-06, Vol.1870 (5), p.167175, Article 167175

2024

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1526-P: Cephalic Phase Insulin Release Requires Alpha Cells

Diabetes (New York, N.Y.), 2023-06, Vol.72 (Supplement_1), p.1

2023

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CSF1R inhibition with PLX5622 affects multiple immune cell compartments and induces tissue-specific metabolic effects in lean mice

Diabetologia, 2023-12, Vol.66 (12), p.2292-2306

2023

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Low concentration IL-1β promotes islet amyloid formation by increasing hIAPP release from humanised mouse islets in vitro

Diabetologia, 2020-11, Vol.63 (11), p.2385-2395

2020

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The S20G substitution in hIAPP is more amyloidogenic and cytotoxic than wild-type hIAPP in mouse islets

Diabetologia, 2016-10, Vol.59 (10), p.2166-2171

2016

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Low- and High-Density Lipoproteins Modulate Function, Apoptosis, and Proliferation of Primary Human and Murine Pancreatic β-Cells

Endocrinology (Philadelphia), 2009-10, Vol.150 (10), p.4521-4530

2009

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Inflammation in the Pathophysiology and Therapy of Cardiometabolic Disease

Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells

Cystine/Glutamate antiporter system xc- deficiency impairs macrophage glutathione metabolism and cytokine production

Islet amyloid formation is an important determinant for inducing islet inflammation in high-fat-fed human IAPP transgenic mice

Pancreatic α Cell-Derived Glucagon-Related Peptides Are Required for β Cell Adaptation and Glucose Homeostasis

Free Fatty Acids Induce a Proinflammatory Response in Islets via the Abundantly Expressed Interleukin-1 Receptor I

Prohormone convertase 1/3 deficiency causes obesity due to impaired proinsulin processing

IL-1β promotes adipogenesis by directly targeting adipocyte precursors

β Cell-Specific Deletion of the IL-1 Receptor Antagonist Impairs β Cell Proliferation and Insulin Secretion

Inflammation in obesity, diabetes, and related disorders

Diesel Exhaust Particle (DEP)-induced glucose intolerance is driven by an intestinal innate immune response and NLRP3 activation in mice

Identification of a SIRT1 Mutation in a Family with Type 1 Diabetes

Lung versus gut exposure to air pollution particles differentially affect metabolic health in mice

Islet inflammation in type 2 diabetes

Protocol for isolation and spectral flow cytometry analysis of immune cells from the murine exocrine and endocrine pancreas

IL-1beta promotes the age-associated decline of beta cell function

Targeting colonic macrophages improves glycemic control in high-fat diet-induced obesity

Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation

Cystine/glutamate antiporter System xc- deficiency impairs insulin secretion in mice

Similar metabolic pathways are affected in both Congenital Myasthenic Syndrome-22 and Prader-Willi Syndrome

1526-P: Cephalic Phase Insulin Release Requires Alpha Cells

CSF1R inhibition with PLX5622 affects multiple immune cell compartments and induces tissue-specific metabolic effects in lean mice

Low concentration IL-1β promotes islet amyloid formation by increasing hIAPP release from humanised mouse islets in vitro

The S20G substitution in hIAPP is more amyloidogenic and cytotoxic than wild-type hIAPP in mouse islets

Low- and High-Density Lipoproteins Modulate Function, Apoptosis, and Proliferation of Primary Human and Murine Pancreatic β-Cells

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