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Current Strategies of Antiviral Drug Discovery for COVID-19

Frontiers in molecular biosciences, 2021-05, Vol.8, p.671263-671263

2021

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Development of Lysine Crotonyl‐Mimic Probe to Covalently Identify H3K27Cr Interacting Proteins

Chemistry : a European journal, 2023-11, Vol.29 (62), p.e202301624-n/a

2023

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Mitophagy in metabolic syndrome

The journal of clinical hypertension (Greenwich, Conn.), 2023-05, Vol.25 (5), p.397-403

2023

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From monoclonal antibodies to small molecules: the development of inhibitors targeting the PD-1/PD-L1 pathway

Drug discovery today, 2016-06, Vol.21 (6), p.1027-1036

2016

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A non-viral CRISPR/Cas9 delivery system for therapeutically targeting HBV DNA and pcsk9 in vivo

Cell research, 2017-03, Vol.27 (3), p.440-443

2017

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The effects of artocarpin on wound healing: in vitro and in vivo studies

Scientific reports, 2017-11, Vol.7 (1), p.15599-13, Article 15599

2017

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A GSH-resistant FK228 analogue containing a stable disulfide bond

Bioorganic chemistry, 2024-03, Vol.144, p.107119-107119, Article 107119

2024

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Low expression of microRNA‐340 confers adverse clinical outcome in patients with acute myeloid leukemia

Journal of cellular physiology, 2019-04, Vol.234 (4), p.4200-4205

2019

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Short hairpin RNA-mediated knockdown of nuclear factor erythroid 2-like 3 exhibits tumor-suppressing effects in hepatocellular carcinoma cells

World journal of gastroenterology : WJG, 2019-03, Vol.25 (10), p.1210-1223

2019

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Reversal of bleomycin-induced rat pulmonary fibrosis by a xenograft of human umbilical mesenchymal stem cells from Wharton's jelly

Theranostics, 2019-01, Vol.9 (22), p.6646-6664

2019

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Influence of extrusion tap parameters on the forming quality of internal thread cold extrusion

International journal of advanced manufacturing technology, 2023-04, Vol.125 (9-10), p.4765-4777

2023

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Design, synthesis, and biological evaluation of novel highly selective polo-like kinase 2 inhibitors based on the tetrahydropteridin chemical scaffold

European journal of medicinal chemistry, 2018-01, Vol.143, p.724-731

2018

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Structure-based design and SAR development of novel selective polo-like kinase 1 inhibitors having the tetrahydropteridin scaffold

European journal of medicinal chemistry, 2019-12, Vol.184, p.111769, Article 111769

2019

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The Down-Regulation of MicroRNA-497 Contributes to Cell Growth and Cisplatin Resistance Through PI3K/Akt Pathway in Osteosarcoma

Cellular physiology and biochemistry, 2015-01, Vol.36 (5), p.2051-2062

2015

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Apolipoprotein M Protects Against Lipopolysaccharide-Induced Acute Lung Injury via Sphingosine-1-Phosphate Signaling

Inflammation, 2018-03, Vol.41 (2), p.643-653

2018

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PSGL-1 is an evolutionarily conserved antiviral restriction factor

mBio, 2023-10, Vol.14 (5), p.e0038723-e0038723

2023

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miR-664 negatively regulates PLP2 and promotes cell proliferation and invasion in T-cell acute lymphoblastic leukaemia

Biochemical and biophysical research communications, 2015-04, Vol.459 (2), p.340-345

2015

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Xenograft of Human Umbilical Mesenchymal Stem Cells from Wharton’s Jelly Differentiating into Osteocytes and Reducing Osteoclast Activity Reverses Osteoporosis in Ovariectomized Rats

Cell transplantation, 2018-01, Vol.27 (1), p.194-208

2018

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Preparation of nanofibers with Cu/TiO2/rice husk ash photocatalyst and their degradation of methylene blue under visible light

Journal of polymer research, 2024-07, Vol.31 (7), Article 185

2024

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Chemo-Selective Cys–Pen Disulfide for Proximity-Induced Cysteine Cross-Linking

ACS chemical biology, 2022-03, Vol.17 (3), p.521-528

2022

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Increased apolipoprotein M induced by lack of scavenger receptor BI is not activated via HDL-mediated cholesterol uptake in hepatocytes

Lipids in health and disease, 2018-08, Vol.17 (1), p.200-200, Article 200

2018

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Ginkgolide K promotes astrocyte proliferation and migration after oxygen-glucose deprivation via inducing protective autophagy through the AMPK/mTOR/ULK1 signaling pathway

European journal of pharmacology, 2018-08, Vol.832, p.96-103

2018

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miR-590 promotes cell proliferation and invasion in T-cell acute lymphoblastic leukaemia by inhibiting RB1

Oncotarget, 2016-06, Vol.7 (26), p.39527-39534

2016

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The anti-cancer effects and mechanisms of Scutellaria barbata D. Don on CL1-5 lung cancer cells

Oncotarget, 2017-12, Vol.8 (65), p.109340-109357

2017

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Design, synthesis and bioevalucation of novel 2,3-dihydro-1H-inden-1-amine derivatives as potent and selective human monoamine oxidase B inhibitors based on rasagiline

European journal of medicinal chemistry, 2018-02, Vol.145, p.588-593

2018

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Current Strategies of Antiviral Drug Discovery for COVID-19

Development of Lysine Crotonyl‐Mimic Probe to Covalently Identify H3K27Cr Interacting Proteins

Mitophagy in metabolic syndrome

From monoclonal antibodies to small molecules: the development of inhibitors targeting the PD-1/PD-L1 pathway

A non-viral CRISPR/Cas9 delivery system for therapeutically targeting HBV DNA and pcsk9 in vivo

The effects of artocarpin on wound healing: in vitro and in vivo studies

A GSH-resistant FK228 analogue containing a stable disulfide bond

Low expression of microRNA‐340 confers adverse clinical outcome in patients with acute myeloid leukemia

Short hairpin RNA-mediated knockdown of nuclear factor erythroid 2-like 3 exhibits tumor-suppressing effects in hepatocellular carcinoma cells

Reversal of bleomycin-induced rat pulmonary fibrosis by a xenograft of human umbilical mesenchymal stem cells from Wharton's jelly

Influence of extrusion tap parameters on the forming quality of internal thread cold extrusion

Design, synthesis, and biological evaluation of novel highly selective polo-like kinase 2 inhibitors based on the tetrahydropteridin chemical scaffold

Structure-based design and SAR development of novel selective polo-like kinase 1 inhibitors having the tetrahydropteridin scaffold

The Down-Regulation of MicroRNA-497 Contributes to Cell Growth and Cisplatin Resistance Through PI3K/Akt Pathway in Osteosarcoma

Apolipoprotein M Protects Against Lipopolysaccharide-Induced Acute Lung Injury via Sphingosine-1-Phosphate Signaling

PSGL-1 is an evolutionarily conserved antiviral restriction factor

miR-664 negatively regulates PLP2 and promotes cell proliferation and invasion in T-cell acute lymphoblastic leukaemia

Xenograft of Human Umbilical Mesenchymal Stem Cells from Wharton’s Jelly Differentiating into Osteocytes and Reducing Osteoclast Activity Reverses Osteoporosis in Ovariectomized Rats

Preparation of nanofibers with Cu/TiO2/rice husk ash photocatalyst and their degradation of methylene blue under visible light

Chemo-Selective Cys–Pen Disulfide for Proximity-Induced Cysteine Cross-Linking

Increased apolipoprotein M induced by lack of scavenger receptor BI is not activated via HDL-mediated cholesterol uptake in hepatocytes

Ginkgolide K promotes astrocyte proliferation and migration after oxygen-glucose deprivation via inducing protective autophagy through the AMPK/mTOR/ULK1 signaling pathway

miR-590 promotes cell proliferation and invasion in T-cell acute lymphoblastic leukaemia by inhibiting RB1

The anti-cancer effects and mechanisms of Scutellaria barbata D. Don on CL1-5 lung cancer cells

Design, synthesis and bioevalucation of novel 2,3-dihydro-1H-inden-1-amine derivatives as potent and selective human monoamine oxidase B inhibitors based on rasagiline

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