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Selective Inhibition of Fatty Acid Synthase for Lung Cancer Treatment

Clinical cancer research, 2007-12, Vol.13 (23), p.7139-7145

2007

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Fatty acid synthase inhibition activates AMP-activated protein kinase in SKOV3 human ovarian cancer cells

Cancer research (Chicago, Ill.), 2007-04, Vol.67 (7), p.2964-2971

2007

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Pharmacological glycerol-3-phosphate acyltransferase inhibition decreases food intake and adiposity and increases insulin sensitivity in diet-induced obesity

American journal of physiology. Regulatory, integrative and comparative physiology, 2011-07, Vol.301 (1), p.R116-R130

2011

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Application of a Flexible Synthesis of (5R)-Thiolactomycin To Develop New Inhibitors of Type I Fatty Acid Synthase

Journal of medicinal chemistry, 2005-02, Vol.48 (4), p.946-961

2005

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Design, Synthesis, and Evaluation of 4- and 5-Substituted o -(Octanesulfonamido)benzoic Acids as Inhibitors of Glycerol-3-Phosphate Acyltransferase

MedChemComm, 2014-06, Vol.5 (6), p.826-830

2014

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Design and Synthesis of Small Molecule Glycerol 3-Phosphate Acyltransferase Inhibitors

Journal of medicinal chemistry, 2009-05, Vol.52 (10), p.3317-3327

2009

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Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer cells

Cancer research (Chicago, Ill.), 2003-11, Vol.63 (21), p.7330-7337

2003

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Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability

Human molecular genetics, 2001-01, Vol.10 (2), p.99-105

2001

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Design, synthesis, and biological evaluation of conformationally constrained glycerol 3-phosphate acyltransferase inhibitors

Bioorganic & medicinal chemistry, 2010-09, Vol.18 (17), p.6470-6479

2010

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Novel Upf2p Orthologues Suggest a Functional Link between Translation Initiation and Nonsense Surveillance Complexes

Molecular and Cellular Biology, 2000-12, Vol.20 (23), p.8944-8957

2000

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Pharmacological stimulation of brain carnitine palmitoyl-transferase-1 decreases food intake and body weight

American journal of physiology. Regulatory, integrative and comparative physiology, 2008-02, Vol.294 (2), p.R352-R361

2008

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Design, synthesis, and evaluation of 4- and 5-substituted o-(octanesulfonamido)benzoic acids as inhibitors of glycerol-3-phosphate acyltransferaseElectronic supplementary information (ESI) available: Experimental details including synthetic procedures and characterization data for all novel compounds is available online free of charge. See DOI: 10.1039/c4md00126e

2014-05

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Pharmacological glycerol-3-phosphate acyltransferase inhibition decreases food intake and adiposity and increases insulin sensitivity in diet-induced obesity

American journal of physiology. Regulatory, integrative and comparative physiology, 2011, Vol.70 (1)

2011

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Mammalian Orthologues of a Yeast Regulator of Nonsense Transcript Stability

Proceedings of the National Academy of Sciences - PNAS, 1996-10, Vol.93 (20), p.10928-10932

1996

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Pharmacological stimulation of brain carnitine palmitoyl-transferase-1 decreases food intake and body weight

American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Vol.63 (2)

2008

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Adenovirus Early Region 4 and Viral DNA Synthesis

Virology (New York, N.Y.), 1993-04, Vol.193 (2), p.794-801

1993

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Selective Inhibition of Fatty Acid Synthase for Lung Cancer Treatment

Fatty acid synthase inhibition activates AMP-activated protein kinase in SKOV3 human ovarian cancer cells

Pharmacological glycerol-3-phosphate acyltransferase inhibition decreases food intake and adiposity and increases insulin sensitivity in diet-induced obesity

Application of a Flexible Synthesis of (5R)-Thiolactomycin To Develop New Inhibitors of Type I Fatty Acid Synthase

Design, Synthesis, and Evaluation of 4- and 5-Substituted o -(Octanesulfonamido)benzoic Acids as Inhibitors of Glycerol-3-Phosphate Acyltransferase

Design and Synthesis of Small Molecule Glycerol 3-Phosphate Acyltransferase Inhibitors

Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer cells

Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability

Design, synthesis, and biological evaluation of conformationally constrained glycerol 3-phosphate acyltransferase inhibitors

Novel Upf2p Orthologues Suggest a Functional Link between Translation Initiation and Nonsense Surveillance Complexes

Pharmacological stimulation of brain carnitine palmitoyl-transferase-1 decreases food intake and body weight

Pharmacological glycerol-3-phosphate acyltransferase inhibition decreases food intake and adiposity and increases insulin sensitivity in diet-induced obesity

Mammalian Orthologues of a Yeast Regulator of Nonsense Transcript Stability

Pharmacological stimulation of brain carnitine palmitoyl-transferase-1 decreases food intake and body weight

Adenovirus Early Region 4 and Viral DNA Synthesis

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