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The tau tubulin kinases TTBK1/2 promote accumulation of pathological TDP-43

PLoS genetics, 2014-12, Vol.10 (12), p.e1004803-e1004803

2014

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Molecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury

PloS one, 2014-09, Vol.9 (9), p.e108034

2014

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Genome wide analysis reveals heparan sulfate epimerase modulates TDP-43 proteinopathy

PLoS genetics, 2019-12, Vol.15 (12), p.e1008526

2019

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CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration

Annals of neurology, 2013-07, Vol.74 (1), p.39-52

2013

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Pathological phosphorylation of tau and TDP-43 by TTBK1 and TTBK2 drives neurodegeneration

Molecular neurodegeneration, 2018-02, Vol.13 (1), p.7-7, Article 7

2018

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Tau–RNA complexes inhibit microtubule polymerization and drive disease-relevant conformation change

Brain (London, England : 1878), 2023-08, Vol.146 (8), p.3206-3220

2023

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Tau tubulin kinases in proteinopathy

The FEBS journal, 2019-07, Vol.286 (13), p.2434-2446

2019

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Distinct Poly(A) nucleases have differential impact on sut-2 dependent tauopathy phenotypes

Neurobiology of disease, 2021-01, Vol.147, p.105148-105148, Article 105148

2021

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Pathological tau drives ectopic nuclear speckle scaffold protein SRRM2 accumulation in neuron cytoplasm in Alzheimer's disease

Acta neuropathologica communications, 2021-06, Vol.9 (1), p.117-117, Article 117

2021

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Differential response of the central noradrenergic nervous system to the loss of locus coeruleus neurons in Parkinson's disease and Alzheimer's disease

Brain research, 2011-02, Vol.1373, p.240-252

2011

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Rosiglitazone attenuates learning and memory deficits in Tg2576 Alzheimer mice

Experimental neurology, 2006-06, Vol.199 (2), p.265-273

2006

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Proteomic Identification of Novel Proteins in Cortical Lewy Bodies

Brain pathology (Zurich, Switzerland), 2007-04, Vol.17 (2), p.139-145

2007

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The phosphatase calcineurin regulates pathological TDP-43 phosphorylation

Acta neuropathologica, 2016-10, Vol.132 (4), p.545-561

2016

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PATHOGENIC POTENTIAL OF TDP-43 PROTEINOPATHY IN A MICE MODEL OF ALZHEIMER'S DISEASE

IBRO neuroscience reports, 2023-10, Vol.15, p.S410-S410

2023

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Tau isoform regulation is region- and cell-specific in mouse brain

Journal of comparative neurology (1911), 2008-12, Vol.511 (6), p.788-803

2008

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Truncation of tau at E391 Promotes Early Pathologic Changes in Transgenic Mice

Journal of neuropathology and experimental neurology, 2011-11, Vol.70 (11), p.1006-1019

2011

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Reduced Hippocampal Insulin-Degrading Enzyme in Late-Onset Alzheimer's Disease Is Associated with the Apolipoprotein E-ε4 Allele

The American journal of pathology, 2003, Vol.162 (1), p.313-319

2003

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Effects of Chronic Glucocorticoid Administration on Insulin-Degrading Enzyme and Amyloid-Beta Peptide in the Aged Macaque

Journal of neuropathology and experimental neurology, 2005-02, Vol.64 (2), p.139-146

2005

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From model system to clinical medicine: pathophysiologic links of common proteinopathies

Alzheimer's research & therapy, 2010-09, Vol.2 (5), p.26-26

2010

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High copy wildtype human 1N4R tau expression promotes early pathological tauopathy accompanied by cognitive deficits without progressive neurofibrillary degeneration

Acta neuropathologica communications, 2015-06, Vol.3 (1), p.33-33, Article 33

2015

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R47H Variant of TREM2 Associated With Alzheimer Disease in a Large Late-Onset Family: Clinical, Genetic, and Neuropathological Study

JAMA neurology, 2015-08, Vol.72 (8), p.920

2015

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The role of Tau RNA complex formation in tau function and tauopathy disorders

Alzheimer's & dementia, 2022-12, Vol.18 (S3), p.n/a

2022

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Blast exposure causes dynamic microglial/macrophage responses and microdomains of brain microvessel dysfunction

Neuroscience, 2016-04, Vol.319, p.206-220

2016

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Increased galanin receptor occupancy in Alzheimer’s disease

Neurobiology of aging, 2004-11, Vol.25 (10), p.1309-1314

2004

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Chronic cortisol exposure promotes the development of a GABAergic phenotype in the primate hippocampus

Journal of neurochemistry, 2004-11, Vol.91 (4), p.843-851

2004

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The tau tubulin kinases TTBK1/2 promote accumulation of pathological TDP-43

Molecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury

Genome wide analysis reveals heparan sulfate epimerase modulates TDP-43 proteinopathy

CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration

Pathological phosphorylation of tau and TDP-43 by TTBK1 and TTBK2 drives neurodegeneration

Tau–RNA complexes inhibit microtubule polymerization and drive disease-relevant conformation change

Tau tubulin kinases in proteinopathy

Distinct Poly(A) nucleases have differential impact on sut-2 dependent tauopathy phenotypes

Pathological tau drives ectopic nuclear speckle scaffold protein SRRM2 accumulation in neuron cytoplasm in Alzheimer's disease

Differential response of the central noradrenergic nervous system to the loss of locus coeruleus neurons in Parkinson's disease and Alzheimer's disease

Rosiglitazone attenuates learning and memory deficits in Tg2576 Alzheimer mice

Proteomic Identification of Novel Proteins in Cortical Lewy Bodies

The phosphatase calcineurin regulates pathological TDP-43 phosphorylation

PATHOGENIC POTENTIAL OF TDP-43 PROTEINOPATHY IN A MICE MODEL OF ALZHEIMER'S DISEASE

Tau isoform regulation is region- and cell-specific in mouse brain

Truncation of tau at E391 Promotes Early Pathologic Changes in Transgenic Mice

Reduced Hippocampal Insulin-Degrading Enzyme in Late-Onset Alzheimer's Disease Is Associated with the Apolipoprotein E-ε4 Allele

Effects of Chronic Glucocorticoid Administration on Insulin-Degrading Enzyme and Amyloid-Beta Peptide in the Aged Macaque

From model system to clinical medicine: pathophysiologic links of common proteinopathies

High copy wildtype human 1N4R tau expression promotes early pathological tauopathy accompanied by cognitive deficits without progressive neurofibrillary degeneration

R47H Variant of TREM2 Associated With Alzheimer Disease in a Large Late-Onset Family: Clinical, Genetic, and Neuropathological Study

The role of Tau RNA complex formation in tau function and tauopathy disorders

Blast exposure causes dynamic microglial/macrophage responses and microdomains of brain microvessel dysfunction

Increased galanin receptor occupancy in Alzheimer’s disease

Chronic cortisol exposure promotes the development of a GABAergic phenotype in the primate hippocampus

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