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Cyclic Peptides as Drugs for Intracellular Targets: The Next Frontier in Peptide Therapeutic Development

Chemistry : a European journal, 2021-01, Vol.27 (5), p.1487-1513

2021

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Protein-protein inhibitor designed de novo to target the MEEVD region on the C-terminus of Hsp90 and block co-chaperone activity

Chemical communications (Cambridge, England), 2019-01, Vol.55 (6), p.846-849

2019

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Yo-yo subduction recorded by accessory minerals in the Italian Western Alps

Nature geoscience, 2011-05, Vol.4 (5), p.338-342

2011

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C-terminal heat shock protein 90 modulators produce desirable oncogenic properties

Organic & biomolecular chemistry, 2015-04, Vol.13 (16), p.4627-4631

2015

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Development of a symbiotic culture of bacteria and yeast (SCOBY) farm to manufacture artificial skin for front of neck airway access simulation

Anaesthesia and intensive care, 2024-05, Vol.52 (3), p.184-187

2024

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The first report of direct inhibitors that target the C-terminal MEEVD region on heat shock protein 90

Chemical communications (Cambridge, England), 2016-01, Vol.52 (3), p.501-504

2016

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Regulating the master regulator: Controlling heat shock factor 1 as a chemotherapy approach

Bioorganic & medicinal chemistry letters, 2015-09, Vol.25 (17), p.3409-3414

2015

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Heat Shock Protein Inhibitors: Success Stories

1st ed. 2016., 2016

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C-Terminal HSP90 Inhibitors Block the HIF-1 Hypoxic Response by Degrading HIF-1α through the Oxygen-Dependent Degradation Pathway

Cellular physiology and biochemistry, 2019, Vol.53 (3), p.480-495

2019

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Synthesis of sansalvamide A peptidomimetics: triazole, oxazole, thiazole, and pseudoproline containing compounds

Tetrahedron, 2012-01, Vol.68 (4), p.1029-1051

2012

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Predicting the unpredictable: Recent structure–activity studies on peptide-based macrocycles

Bioorganic chemistry, 2015-06, Vol.60, p.74-97

2015

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N-terminal and C-terminal modulation of Hsp90 produce dissimilar phenotypes

Chemical communications (Cambridge, England), 2015-01, Vol.51 (8), p.1410-1413

2015

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Solid phase versus solution phase synthesis of heterocyclic macrocycles

Molecules (Basel, Switzerland), 2013-01, Vol.18 (1), p.1111-1121

2013

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Macrocyclic inhibitors of hsp90

Current topics in medicinal chemistry, 2010-10, Vol.10 (14), p.1380-1402

2010

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Improving the Cell Permeability of Polar Cyclic Peptides by Replacing Residues with Alkylated Amino Acids, Asparagines, and d‑Amino Acids

Organic letters, 2018-02, Vol.20 (3), p.506-509

2018

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Delivering bioactive cyclic peptides that target Hsp90 as prodrugs

Journal of enzyme inhibition and medicinal chemistry, 2019-01, Vol.34 (1), p.728-739

2019

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Mechanistic Studies of Sansalvamide A-Amide: An Allosteric Modulator of Hsp90

ACS medicinal chemistry letters, 2010-04, Vol.1 (1), p.4-8

2010

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Hsp90 Mediates Membrane Deformation and Exosome Release

Molecular cell, 2018-09, Vol.71 (5), p.689-702.e9

2018

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Delivering hydrophilic peptide inhibitors of heat shock protein 70 into cancer cells

Bioorganic chemistry, 2022-05, Vol.122, p.105713-105713, Article 105713

2022

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The annual incidence of diabetic complications in a population of patients with Type 1 and Type 2 diabetes

Diabetic medicine, 2005-03, Vol.22 (3), p.348-352

2005

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A retrospective observational study of patients with dilated cardiomyopathy undergoing non-cardiac surgery

Anaesthesia and intensive care, 2017-09, Vol.45 (5), p.619-623

2017

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Heat shock proteins 27, 40, and 70 as combinational and dual therapeutic cancer targets

Bioorganic & medicinal chemistry letters, 2013-04, Vol.23 (7), p.1923-1928

2013

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Real time monitoring of peptide delivery in vitro using high payload pH responsive nanogels

Polymer chemistry, 2020-01, Vol.11 (2), p.425-432

2020

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Regulating the cytoprotective response in cancer cells using simultaneous inhibition of Hsp90 and Hsp70

Organic & biomolecular chemistry, 2015-02, Vol.13 (7), p.2108-2116

2015

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Redefining the Phenotype of Heat Shock Protein 90 (Hsp90) Inhibitors

Chemistry : a European journal, 2017-02, Vol.23 (9), p.2010-2013

2017

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Cyclic Peptides as Drugs for Intracellular Targets: The Next Frontier in Peptide Therapeutic Development

Protein-protein inhibitor designed de novo to target the MEEVD region on the C-terminus of Hsp90 and block co-chaperone activity

Yo-yo subduction recorded by accessory minerals in the Italian Western Alps

C-terminal heat shock protein 90 modulators produce desirable oncogenic properties

Development of a symbiotic culture of bacteria and yeast (SCOBY) farm to manufacture artificial skin for front of neck airway access simulation

The first report of direct inhibitors that target the C-terminal MEEVD region on heat shock protein 90

Regulating the master regulator: Controlling heat shock factor 1 as a chemotherapy approach

Heat Shock Protein Inhibitors: Success Stories

C-Terminal HSP90 Inhibitors Block the HIF-1 Hypoxic Response by Degrading HIF-1α through the Oxygen-Dependent Degradation Pathway

Synthesis of sansalvamide A peptidomimetics: triazole, oxazole, thiazole, and pseudoproline containing compounds

Predicting the unpredictable: Recent structure–activity studies on peptide-based macrocycles

N-terminal and C-terminal modulation of Hsp90 produce dissimilar phenotypes

Solid phase versus solution phase synthesis of heterocyclic macrocycles

Macrocyclic inhibitors of hsp90

Improving the Cell Permeability of Polar Cyclic Peptides by Replacing Residues with Alkylated Amino Acids, Asparagines, and d‑Amino Acids

Delivering bioactive cyclic peptides that target Hsp90 as prodrugs

Mechanistic Studies of Sansalvamide A-Amide: An Allosteric Modulator of Hsp90

Hsp90 Mediates Membrane Deformation and Exosome Release

Delivering hydrophilic peptide inhibitors of heat shock protein 70 into cancer cells

The annual incidence of diabetic complications in a population of patients with Type 1 and Type 2 diabetes

A retrospective observational study of patients with dilated cardiomyopathy undergoing non-cardiac surgery

Heat shock proteins 27, 40, and 70 as combinational and dual therapeutic cancer targets

Real time monitoring of peptide delivery in vitro using high payload pH responsive nanogels

Regulating the cytoprotective response in cancer cells using simultaneous inhibition of Hsp90 and Hsp70

Redefining the Phenotype of Heat Shock Protein 90 (Hsp90) Inhibitors

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