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ROCK inhibitors upregulate the neuroprotective Parkin-mediated mitophagy pathway

Nature communications, 2020-01, Vol.11 (1), p.88-14, Article 88

2020

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An AI-guided screen identifies probucol as an enhancer of mitophagy through modulation of lipid droplets

PLoS biology, 2023-03, Vol.21 (3), p.e3001977

2023

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Deubiquitinating enzymes regulate PARK2-mediated mitophagy

Autophagy, 2015-04, Vol.11 (4), p.595-606

2015

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The Mitochondrial Rhomboid Protease PARL Is Regulated by PDK2 to Integrate Mitochondrial Quality Control and Metabolism

Cell reports (Cambridge), 2017-02, Vol.18 (6), p.1458-1472

2017

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ROS-induced mitochondrial depolarization initiates PARK2/PARKIN-dependent mitochondrial degradation by autophagy

Autophagy, 2012-10, Vol.8 (10), p.1462-1476

2012

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Caenorhabditis elegans is a useful model for anthelmintic discovery

Nature communications, 2015-06, Vol.6 (1), p.7485, Article 7485

2015

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Meiotic viral attenuation through an ancestral apoptotic pathway

Proceedings of the National Academy of Sciences - PNAS, 2019-08, Vol.116 (33), p.16454-16462

2019

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Deubiquitinating enzyme USP30 maintains basal peroxisome abundance by regulating pexophagy

The Journal of cell biology, 2019-03, Vol.218 (3), p.798-807

2019

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The atypical cadherin fat directly regulates mitochondrial function and metabolic state

Cell, 2014-09, Vol.158 (6), p.1293-1308

2014

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PGAM5 is an MFN2 phosphatase that plays an essential role in the regulation of mitochondrial dynamics

Cell reports (Cambridge), 2023-08, Vol.42 (8), p.112895-112895, Article 112895

2023

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Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease

Human molecular genetics, 2011-05, Vol.20 (10), p.1966-1974

2011

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Mitochondrial membrane remodelling regulated by a conserved rhomboid protease

Nature (London), 2003-05, Vol.423 (6939), p.537-541

2003

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Inflammation Dampened by Gelatinase a Cleavage of Monocyte Chemoattractant Protein-3

Science (American Association for the Advancement of Science), 2000-08, Vol.289 (5482), p.1202-1206

2000

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Protocol for evaluating mitochondrial morphology changes in response to CCCP-induced stress through open-source image processing software

STAR protocols, 2023-12, Vol.4 (4), p.102745-102745, Article 102745

2023

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Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo

Blood, 2002-08, Vol.100 (4), p.1160-1167

2002

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From jeopardy champion to drug discovery; semantic similarity artificial intelligence

Autophagy, 2024-04, Vol.20 (4), p.935-937

2024

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Phospholipid Association Is Essential for Dynamin-related Protein Mgm1 to Function in Mitochondrial Membrane Fusion

The Journal of biological chemistry, 2009-10, Vol.284 (42), p.28682-28686

2009

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HIV-induced metalloproteinase processing of the chemokine stromal cell derived factor-1 causes neurodegeneration

Nature neuroscience, 2003-10, Vol.6 (10), p.1064-1071

2003

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A Drosophila mutant of LETM1, a candidate gene for seizures in Wolf-Hirschhorn syndrome

Human molecular genetics, 2010-03, Vol.19 (6), p.987-1000

2010

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Author Correction: Caenorhabditis elegans is a useful model for anthelmintic discovery

Nature communications, 2020-07, Vol.11 (1), p.1-1, Article 3779

2020

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Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin

Disease models & mechanisms, 2008-09, Vol.1 (2-3), p.168-174

2008

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USP30: protector of peroxisomes and mitochondria

Molecular & cellular oncology, 2019-05, Vol.6 (3), p.1600350-1600350

2019

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Phosphatidylserine Decarboxylase 1 (Psd1) Promotes Mitochondrial Fusion by Regulating the Biophysical Properties of the Mitochondrial Membrane and Alternative Topogenesis of Mitochondrial Genome Maintenance Protein 1 (Mgm1)

The Journal of biological chemistry, 2012-11, Vol.287 (48), p.40131-40139

2012

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PRKN/parkin-mediated mitophagy is induced by the probiotics Saccharomyces boulardii and Lactococcus lactis

Autophagy, 2023-07, Vol.19 (7), p.2094-2110

2023

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A Rhomboid in the Rough: Potent Inhibitors for a Previously Undruggable Target

Cell chemical biology, 2017-12, Vol.24 (12), p.1431-1433

2017

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ROCK inhibitors upregulate the neuroprotective Parkin-mediated mitophagy pathway

An AI-guided screen identifies probucol as an enhancer of mitophagy through modulation of lipid droplets

Deubiquitinating enzymes regulate PARK2-mediated mitophagy

The Mitochondrial Rhomboid Protease PARL Is Regulated by PDK2 to Integrate Mitochondrial Quality Control and Metabolism

ROS-induced mitochondrial depolarization initiates PARK2/PARKIN-dependent mitochondrial degradation by autophagy

Caenorhabditis elegans is a useful model for anthelmintic discovery

Meiotic viral attenuation through an ancestral apoptotic pathway

Deubiquitinating enzyme USP30 maintains basal peroxisome abundance by regulating pexophagy

The atypical cadherin fat directly regulates mitochondrial function and metabolic state

PGAM5 is an MFN2 phosphatase that plays an essential role in the regulation of mitochondrial dynamics

Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease

Mitochondrial membrane remodelling regulated by a conserved rhomboid protease

Inflammation Dampened by Gelatinase a Cleavage of Monocyte Chemoattractant Protein-3

Protocol for evaluating mitochondrial morphology changes in response to CCCP-induced stress through open-source image processing software

Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo

From jeopardy champion to drug discovery; semantic similarity artificial intelligence

Phospholipid Association Is Essential for Dynamin-related Protein Mgm1 to Function in Mitochondrial Membrane Fusion

HIV-induced metalloproteinase processing of the chemokine stromal cell derived factor-1 causes neurodegeneration

A Drosophila mutant of LETM1, a candidate gene for seizures in Wolf-Hirschhorn syndrome

Author Correction: Caenorhabditis elegans is a useful model for anthelmintic discovery

Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin

USP30: protector of peroxisomes and mitochondria

Phosphatidylserine Decarboxylase 1 (Psd1) Promotes Mitochondrial Fusion by Regulating the Biophysical Properties of the Mitochondrial Membrane and Alternative Topogenesis of Mitochondrial Genome Maintenance Protein 1 (Mgm1)

PRKN/parkin-mediated mitophagy is induced by the probiotics Saccharomyces boulardii and Lactococcus lactis

A Rhomboid in the Rough: Potent Inhibitors for a Previously Undruggable Target

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