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Three-Dimensional Models of Wild-Type and Mutated Forms of Cytochrome P450 14α-Sterol Demethylases from Aspergillus fumigatus and Candida albicans Provide Insights into Posaconazole Binding

Antimicrobial Agents and Chemotherapy, 2004-02, Vol.48 (2), p.568-574

2004

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Application of Real-Time Quantitative PCR to Molecular Analysis of Candida albicans Strains Exhibiting Reduced Susceptibility to Azoles

Antimicrobial Agents and Chemotherapy, 2004-06, Vol.48 (6), p.2124-2131

2004

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Impact of Antifungal Prophylaxis on Colonization and Azole Susceptibility of Candida Species

Antimicrobial Agents and Chemotherapy, 2009-12, Vol.53 (12), p.5026-5034

2009

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Discovery of a Novel Class of Orally Active Antifungal β-1,3-d-Glucan Synthase Inhibitors

Antimicrobial Agents and Chemotherapy, 2011-11, Vol.55 (11), p.5099-5106

2011

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Mapping and characterization of vicriviroc resistance mutations from HIV-1 isolated from treatment-experienced subjects enrolled in a phase II study (VICTOR-E1)

Journal of acquired immune deficiency syndromes (1999), 2011-03, Vol.56 (3), p.222

2011

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Posaconazole Is a Potent Inhibitor of Sterol 14α-Demethylation in Yeasts and Molds

Antimicrobial Agents and Chemotherapy, 2004-10, Vol.48 (10), p.3690-3696

2004

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A Novel Site of Antibiotic Action in the Ribosome: Interaction of Evernimicin with the Large Ribosomal Subunit

Proceedings of the National Academy of Sciences - PNAS, 2001-03, Vol.98 (7), p.3726-3731

2001

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Clinical Evaluation of the Sensititre YeastOne Plate for Testing Susceptibility of Filamentous Fungi to Posaconazole

Journal of Clinical Microbiology, 2007-06, Vol.45 (6), p.2000-2001

2007

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Molecular Basis for Enhanced Activity of Posaconazole against Absidia corymbifera and Rhizopus oryzae

Antimicrobial Agents and Chemotherapy, 2006-11, Vol.50 (11), p.3917-3919

2006

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Activity of newer triazoles against Histoplasma capsulatum from patients with AIDS who failed fluconazole

Journal of antimicrobial chemotherapy, 2006-06, Vol.57 (6), p.1235-1239

2006

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The Molybdate-Responsive Escherichia coli ModE Transcriptional Regulator Coordinates Periplasmic Nitrate Reductase (napFDAGHBC) Operon Expression with Nitrate and Molybdate Availability

Journal of Bacteriology, 2002-06, Vol.184 (12), p.3253-3259

2002

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Evernimicin Binds Exclusively to the 50S Ribosomal Subunit and Inhibits Translation in Cell-Free Systems Derived from both Gram-Positive and Gram-Negative Bacteria

Antimicrobial Agents and Chemotherapy, 2000-05, Vol.44 (5), p.1121-1126

2000

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Incidence of High-Level Evernimicin Resistance in Enterococcus faecium among Food Animals and Humans

Antimicrobial Agents and Chemotherapy, 2002-09, Vol.46 (9), p.3088-3090

2002

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Inactivation of Sterol Δ5,6-Desaturase Attenuates Virulence in Candida albicans

Antimicrobial Agents and Chemotherapy, 2005-09, Vol.49 (9), p.3646-3651

2005

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Effects of Mutations in Ribosomal Protein L16 on Susceptibility and Accumulation of Evernimicin

Antimicrobial Agents and Chemotherapy, 2001-01, Vol.45 (1), p.79-83

2001

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Changes in susceptibility to posaconazole in clinical isolates of Candida albicans

Journal of antimicrobial chemotherapy, 2004-01, Vol.53 (1), p.74-80

2004

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Characterization of the ModE DNA‐binding sites in the control regions of modABCD and moaABCDE of Escherichia coli

Molecular microbiology, 1997-02, Vol.23 (3), p.515-524

1997

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SAR studies of pyridazinone derivatives as novel glucan synthase inhibitors

Bioorganic & medicinal chemistry letters, 2011-05, Vol.21 (10), p.2890-2893

2011

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Lead optimization of a sulfonylurea-based piperazine pyridazinone series of glucan synthase inhibitors

Bioorganic & medicinal chemistry letters, 2012-07, Vol.22 (14), p.4896-4899

2012

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The synthesis and structure–activity relationship of pyridazinones as glucan synthase inhibitors

Bioorganic & medicinal chemistry letters, 2011-03, Vol.21 (6), p.1819-1822

2011

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The optimization of pyridazinone series of glucan synthase inhibitors

Bioorganic & medicinal chemistry letters, 2012-08, Vol.22 (16), p.5268-5271

2012

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Functional Dissection of the Molybdate-Responsive Transcription Regulator, ModE, from Escherichia coli

Journal of Bacteriology, 1998-09, Vol.180 (17), p.4638-4643

1998

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Anaerobic regulation of the Escherichia coli dmsABC operon requires the molybdate‐responsive regulator ModE

Molecular microbiology, 1998-01, Vol.27 (1), p.197-208

1998

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Expression of the heme biosynthetic pathway genes hemCD, hemH, hemM and hemA of Escherichia coli

FEMS microbiology letters, 1997, Vol.146 (1), p.143-148

1997

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The Escherichia coli modE gene: effect of modE mutations on molybdate dependent modA expression

FEMS microbiology letters, 1996-11, Vol.145 (1), p.117-123

1996

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Three-Dimensional Models of Wild-Type and Mutated Forms of Cytochrome P450 14α-Sterol Demethylases from Aspergillus fumigatus and Candida albicans Provide Insights into Posaconazole Binding

Application of Real-Time Quantitative PCR to Molecular Analysis of Candida albicans Strains Exhibiting Reduced Susceptibility to Azoles

Impact of Antifungal Prophylaxis on Colonization and Azole Susceptibility of Candida Species

Discovery of a Novel Class of Orally Active Antifungal β-1,3-d-Glucan Synthase Inhibitors

Mapping and characterization of vicriviroc resistance mutations from HIV-1 isolated from treatment-experienced subjects enrolled in a phase II study (VICTOR-E1)

Posaconazole Is a Potent Inhibitor of Sterol 14α-Demethylation in Yeasts and Molds

A Novel Site of Antibiotic Action in the Ribosome: Interaction of Evernimicin with the Large Ribosomal Subunit

Clinical Evaluation of the Sensititre YeastOne Plate for Testing Susceptibility of Filamentous Fungi to Posaconazole

Molecular Basis for Enhanced Activity of Posaconazole against Absidia corymbifera and Rhizopus oryzae

Activity of newer triazoles against Histoplasma capsulatum from patients with AIDS who failed fluconazole

The Molybdate-Responsive Escherichia coli ModE Transcriptional Regulator Coordinates Periplasmic Nitrate Reductase (napFDAGHBC) Operon Expression with Nitrate and Molybdate Availability

Evernimicin Binds Exclusively to the 50S Ribosomal Subunit and Inhibits Translation in Cell-Free Systems Derived from both Gram-Positive and Gram-Negative Bacteria

Incidence of High-Level Evernimicin Resistance in Enterococcus faecium among Food Animals and Humans

Inactivation of Sterol Δ5,6-Desaturase Attenuates Virulence in Candida albicans

Effects of Mutations in Ribosomal Protein L16 on Susceptibility and Accumulation of Evernimicin

Changes in susceptibility to posaconazole in clinical isolates of Candida albicans

Characterization of the ModE DNA‐binding sites in the control regions of modABCD and moaABCDE of Escherichia coli

SAR studies of pyridazinone derivatives as novel glucan synthase inhibitors

Lead optimization of a sulfonylurea-based piperazine pyridazinone series of glucan synthase inhibitors

The synthesis and structure–activity relationship of pyridazinones as glucan synthase inhibitors

The optimization of pyridazinone series of glucan synthase inhibitors

Functional Dissection of the Molybdate-Responsive Transcription Regulator, ModE, from Escherichia coli

Anaerobic regulation of the Escherichia coli dmsABC operon requires the molybdate‐responsive regulator ModE

Expression of the heme biosynthetic pathway genes hemCD, hemH, hemM and hemA of Escherichia coli

The Escherichia coli modE gene: effect of modE mutations on molybdate dependent modA expression

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