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The Effect of Substrate Stiffness, Thickness, and Cross-Linking Density on Osteogenic Cell Behavior

Biophysical journal, 2015-04, Vol.108 (7), p.1604-1612

2015

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Investigating the interplay between substrate stiffness and ligand chemistry in directing mesenchymal stem cell differentiation within 3D macro-porous substrates

Biomaterials, 2018-07, Vol.171, p.23-33

2018

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Fluid flow in the osteocyte mechanical environment: a fluid–structure interaction approach

Biomechanics and modeling in mechanobiology, 2014-01, Vol.13 (1), p.85-97

2014

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Estrogen withdrawal alters cytoskeletal and primary ciliary dynamics resulting in increased Hedgehog and osteoclastogenic paracrine signalling in osteocytes

Scientific reports, 2021-04, Vol.11 (1), p.9272-9272, Article 9272

2021

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Altered Mechanical Environment of Bone Cells in an Animal Model of Short- and Long-Term Osteoporosis

Biophysical journal, 2015-04, Vol.108 (7), p.1587-1598

2015

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model for the role of integrins in flow induced mechanotransduction in osteocytes

Proceedings of the National Academy of Sciences - PNAS, 2007-10, Vol.104 (40), p.15941-15946

2007

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A mechanobiological model of bone metastasis reveals that mechanical stimulation inhibits the pro-osteolytic effects of breast cancer cells

Cell reports (Cambridge), 2024-05, Vol.43 (5), p.114043, Article 114043

2024

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Osteocytes and Estrogen Deficiency

Current osteoporosis reports, 2021-12, Vol.19 (6), p.592-603

McNamara, Laoise M.

2021

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Mechanisms of osteocyte stimulation in osteoporosis

Journal of the mechanical behavior of biomedical materials, 2016-09, Vol.62, p.158-168

2016

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Thermally induced osteocyte damage initiates a remodelling signaling cascade

PloS one, 2015-03, Vol.10 (3), p.e0119652-e0119652

2015

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The effect of marrow secretome and culture environment on the rate of metastatic breast cancer cell migration in two and three dimensions

Molecular biology of the cell, 2021-05, Vol.32 (10), p.1009-1019

2021

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Primary Cilia Exist in a Small Fraction of Cells in Trabecular Bone and Marrow

Calcified tissue international, 2015-01, Vol.96 (1), p.65-72

2015

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Bone mechanical properties and changes with osteoporosis

Injury, 2016-06, Vol.47 (Suppl 2), p.S11-S20

2016

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Temporal and spatial changes in bone mineral content and mechanical properties during breast-cancer bone metastases

Bone Reports, 2022-12, Vol.17, p.101597-101597, Article 101597

2022

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A Developmental Engineering-Based Approach to Bone Repair: Endochondral Priming Enhances Vascularization and New Bone Formation in a Critical Size Defect

Frontiers in bioengineering and biotechnology, 2020-03, Vol.8, p.230-230

2020

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Alterations in osteocyte mediated osteoclastogenesis during estrogen deficiency and under ROCK-II inhibition: An in vitro study using a novel postmenopausal multicellular niche model

Experimental cell research, 2020-07, Vol.392 (1), p.112005, Article 112005

2020

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Instrumental in Surgery: A Narrative Review on Energy-based Surgical Cutting Devices and Surgical Smoke

Annals of surgery, 2023-09, Vol.278 (3), p.e457-e465

2023

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The effect of equiaxial stretching on the osteogenic differentiation and mechanical properties of human adipose stem cells

Journal of the mechanical behavior of biomedical materials, 2017-08, Vol.72, p.38-48

2017

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Computational Investigation of Vessel Injury Due to Catheter Tracking During Transcatheter Aortic Valve Replacement

Annals of biomedical engineering, 2024-06, Vol.52 (6), p.1554-1567

2024

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ROCK-II inhibition suppresses impaired mechanobiological responses in early estrogen deficient osteoblasts

Experimental cell research, 2020-11, Vol.396 (1), p.112264-112264, Article 112264

2020

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A Novel 3D Osteoblast and Osteocyte Model Revealing Changes in Mineralization and Pro-osteoclastogenic Paracrine Signaling During Estrogen Deficiency

Frontiers in bioengineering and biotechnology, 2020-06, Vol.8, p.601

2020

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Estrogen deficiency attenuates fluid flow‐induced [Ca2+]i oscillations and mechanoresponsiveness of MLO‐Y4 osteocytes

The FASEB journal, 2017-07, Vol.31 (7), p.3027-3039

2017

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Quantification of fluid shear stress in bone tissue engineering scaffolds with spherical and cubical pore architectures

Biomechanics and modeling in mechanobiology, 2016-06, Vol.15 (3), p.561-577

2016

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Integrins in Osteocyte Biology and Mechanotransduction

Current osteoporosis reports, 2019-08, Vol.17 (4), p.195-206

2019

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Estrogen deficiency impairs integrin αvβ3-mediated mechanosensation by osteocytes and alters osteoclastogenic paracrine signalling

Scientific reports, 2019-03, Vol.9 (1), p.4654-4654, Article 4654

2019

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The Effect of Substrate Stiffness, Thickness, and Cross-Linking Density on Osteogenic Cell Behavior

Investigating the interplay between substrate stiffness and ligand chemistry in directing mesenchymal stem cell differentiation within 3D macro-porous substrates

Fluid flow in the osteocyte mechanical environment: a fluid–structure interaction approach

Estrogen withdrawal alters cytoskeletal and primary ciliary dynamics resulting in increased Hedgehog and osteoclastogenic paracrine signalling in osteocytes

Altered Mechanical Environment of Bone Cells in an Animal Model of Short- and Long-Term Osteoporosis

model for the role of integrins in flow induced mechanotransduction in osteocytes

A mechanobiological model of bone metastasis reveals that mechanical stimulation inhibits the pro-osteolytic effects of breast cancer cells

Osteocytes and Estrogen Deficiency

Mechanisms of osteocyte stimulation in osteoporosis

Thermally induced osteocyte damage initiates a remodelling signaling cascade

The effect of marrow secretome and culture environment on the rate of metastatic breast cancer cell migration in two and three dimensions

Primary Cilia Exist in a Small Fraction of Cells in Trabecular Bone and Marrow

Bone mechanical properties and changes with osteoporosis

Temporal and spatial changes in bone mineral content and mechanical properties during breast-cancer bone metastases

A Developmental Engineering-Based Approach to Bone Repair: Endochondral Priming Enhances Vascularization and New Bone Formation in a Critical Size Defect

Alterations in osteocyte mediated osteoclastogenesis during estrogen deficiency and under ROCK-II inhibition: An in vitro study using a novel postmenopausal multicellular niche model

Instrumental in Surgery: A Narrative Review on Energy-based Surgical Cutting Devices and Surgical Smoke

The effect of equiaxial stretching on the osteogenic differentiation and mechanical properties of human adipose stem cells

Computational Investigation of Vessel Injury Due to Catheter Tracking During Transcatheter Aortic Valve Replacement

ROCK-II inhibition suppresses impaired mechanobiological responses in early estrogen deficient osteoblasts

A Novel 3D Osteoblast and Osteocyte Model Revealing Changes in Mineralization and Pro-osteoclastogenic Paracrine Signaling During Estrogen Deficiency

Estrogen deficiency attenuates fluid flow‐induced [Ca2+]i oscillations and mechanoresponsiveness of MLO‐Y4 osteocytes

Quantification of fluid shear stress in bone tissue engineering scaffolds with spherical and cubical pore architectures

Integrins in Osteocyte Biology and Mechanotransduction

Estrogen deficiency impairs integrin αvβ3-mediated mechanosensation by osteocytes and alters osteoclastogenic paracrine signalling

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