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Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure

American journal of physiology. Lung cellular and molecular physiology, 2009-12, Vol.297 (6), p.L1013-L1032

2009

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Formation of Plexiform Lesions in Experimental Severe Pulmonary Arterial Hypertension

Circulation (New York, N.Y.), 2010-06, Vol.121 (25), p.2747-2754

2010

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Inhibition of Glucose-6-Phosphate Dehydrogenase Activity Attenuates Right Ventricle Pressure and Hypertrophy Elicited by VEGFR Inhibitor + Hypoxia

The Journal of pharmacology and experimental therapeutics, 2021-05, Vol.377 (2), p.284-292

2021

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MicroRNA-140 is elevated and mitofusin-1 is downregulated in the right ventricle of the Sugen5416/hypoxia/normoxia model of pulmonary arterial hypertension

American journal of physiology. Heart and circulatory physiology, 2016-09, Vol.311 (3), p.H689-H698

2016

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Lipid nanoparticle delivery of a microRNA-145 inhibitor improves experimental pulmonary hypertension

Journal of controlled release, 2015-07, Vol.210, p.67-75

2015

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Cellular and Molecular Basis of Pulmonary Arterial Hypertension

Journal of the American College of Cardiology, 2009-06, Vol.54 (1), p.S20-S31

2009

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Fifty Years of Monocrotaline-Induced Pulmonary Hypertension: What Has It Meant to the Field?

Chest, 2017-12, Vol.152 (6), p.1106-1108

2017

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Hypoxia-induced glucose-6-phosphate dehydrogenase overexpression and -activation in pulmonary artery smooth muscle cells: implication in pulmonary hypertension

American journal of physiology. Lung cellular and molecular physiology, 2015-02, Vol.308 (3), p.L287-L300

2015

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Liposomal fasudil, a rho-kinase inhibitor, for prolonged pulmonary preferential vasodilation in pulmonary arterial hypertension

Journal of controlled release, 2013-04, Vol.167 (2), p.189-199

2013

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Haemodynamic unloading reverses occlusive vascular lesions in severe pulmonary hypertension

Cardiovascular research, 2016-07, Vol.111 (1), p.16-25

2016

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Increased Reactive Oxygen Species, Metabolic Maladaptation, and Autophagy Contribute to Pulmonary Arterial Hypertension–Induced Ventricular Hypertrophy and Diastolic Heart Failure

Hypertension (Dallas, Tex. 1979), 2014-12, Vol.64 (6), p.1266-1274

2014

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Inhaled combination of sildenafil and rosiglitazone improves pulmonary hemodynamics, cardiac function, and arterial remodeling

American journal of physiology. Lung cellular and molecular physiology, 2019-01, Vol.316 (1), p.L119-L130

2019

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Hypoxic activation of glucose-6-phosphate dehydrogenase controls the expression of genes involved in the pathogenesis of pulmonary hypertension through the regulation of DNA methylation

American journal of physiology. Lung cellular and molecular physiology, 2020-04, Vol.318 (4), p.L773-L786

2020

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Inhaled sildenafil as an alternative to oral sildenafil in the treatment of pulmonary arterial hypertension (PAH)

Journal of controlled release, 2017-03, Vol.250, p.96-106

2017

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Temporal hemodynamic and histological progression in Sugen5416/hypoxia/normoxia-exposed pulmonary arterial hypertensive rats

American journal of physiology. Heart and circulatory physiology, 2014-01, Vol.306 (2), p.H243-H250

2014

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Rho Kinase-Mediated Vasoconstriction Is Important in Severe Occlusive Pulmonary Arterial Hypertension in Rats

Circulation research, 2007-03, Vol.100 (6), p.923-929

2007

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Dehydroepiandrosterone restores right ventricular structure and function in rats with severe pulmonary arterial hypertension

American journal of physiology. Heart and circulatory physiology, 2013-06, Vol.304 (12), p.H1708-H1718

2013

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CAR, a Homing Peptide, Prolongs Pulmonary Preferential Vasodilation by Increasing Pulmonary Retention and Reducing Systemic Absorption of Liposomal Fasudil

Molecular pharmaceutics, 2019-08, Vol.16 (8), p.3414-3429

2019

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Pulmonary-arterial-hypertension (PAH)-on-a-chip: fabrication, validation and application

Lab on a chip, 2020-09, Vol.2 (18), p.3334-3345

2020

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How does pulmonary endarterectomy cure CTEPH: A clue to cure PAH?

American journal of physiology. Lung cellular and molecular physiology, 2016-10, Vol.311 (4), p.L766-L769

2016

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Aneurysm-type plexiform lesions form in supernumerary arteries in pulmonary arterial hypertension: potential therapeutic implications

American journal of physiology. Lung cellular and molecular physiology, 2019-12, Vol.317 (6), p.L805-L815

2019

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Pulmonary vascular dysfunction secondary to pulmonary arterial hypertension: insights gained through retrograde perfusion

American journal of physiology. Lung cellular and molecular physiology, 2018-05, Vol.314 (5), p.L835-L845

2018

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Repurposing rosiglitazone, a PPAR-γ agonist and oral antidiabetic, as an inhaled formulation, for the treatment of PAH

Journal of controlled release, 2018-06, Vol.280, p.113-123

2018

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Cocktail of Superoxide Dismutase and Fasudil Encapsulated in Targeted Liposomes Slows PAH Progression at a Reduced Dosing Frequency

Molecular pharmaceutics, 2017-03, Vol.14 (3), p.830-841

2017

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Serotonin passes through myoendothelial gap junctions to promote pulmonary arterial smooth muscle cell differentiation

American journal of physiology. Lung cellular and molecular physiology, 2012-11, Vol.303 (9), p.L767-L777

2012

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Hypertension, Pulmonary - Physiopathology
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Pulmonary Hypertension. Acute Cor Pulmonale. Pulmonary Embolism. Pulmonary Vascular Diseases
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Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure

Formation of Plexiform Lesions in Experimental Severe Pulmonary Arterial Hypertension

Inhibition of Glucose-6-Phosphate Dehydrogenase Activity Attenuates Right Ventricle Pressure and Hypertrophy Elicited by VEGFR Inhibitor + Hypoxia

MicroRNA-140 is elevated and mitofusin-1 is downregulated in the right ventricle of the Sugen5416/hypoxia/normoxia model of pulmonary arterial hypertension

Lipid nanoparticle delivery of a microRNA-145 inhibitor improves experimental pulmonary hypertension

Cellular and Molecular Basis of Pulmonary Arterial Hypertension

Fifty Years of Monocrotaline-Induced Pulmonary Hypertension: What Has It Meant to the Field?

Hypoxia-induced glucose-6-phosphate dehydrogenase overexpression and -activation in pulmonary artery smooth muscle cells: implication in pulmonary hypertension

Liposomal fasudil, a rho-kinase inhibitor, for prolonged pulmonary preferential vasodilation in pulmonary arterial hypertension

Haemodynamic unloading reverses occlusive vascular lesions in severe pulmonary hypertension

Increased Reactive Oxygen Species, Metabolic Maladaptation, and Autophagy Contribute to Pulmonary Arterial Hypertension–Induced Ventricular Hypertrophy and Diastolic Heart Failure

Inhaled combination of sildenafil and rosiglitazone improves pulmonary hemodynamics, cardiac function, and arterial remodeling

Hypoxic activation of glucose-6-phosphate dehydrogenase controls the expression of genes involved in the pathogenesis of pulmonary hypertension through the regulation of DNA methylation

Inhaled sildenafil as an alternative to oral sildenafil in the treatment of pulmonary arterial hypertension (PAH)

Temporal hemodynamic and histological progression in Sugen5416/hypoxia/normoxia-exposed pulmonary arterial hypertensive rats

Rho Kinase-Mediated Vasoconstriction Is Important in Severe Occlusive Pulmonary Arterial Hypertension in Rats

Dehydroepiandrosterone restores right ventricular structure and function in rats with severe pulmonary arterial hypertension

CAR, a Homing Peptide, Prolongs Pulmonary Preferential Vasodilation by Increasing Pulmonary Retention and Reducing Systemic Absorption of Liposomal Fasudil

Pulmonary-arterial-hypertension (PAH)-on-a-chip: fabrication, validation and application

How does pulmonary endarterectomy cure CTEPH: A clue to cure PAH?

Aneurysm-type plexiform lesions form in supernumerary arteries in pulmonary arterial hypertension: potential therapeutic implications

Pulmonary vascular dysfunction secondary to pulmonary arterial hypertension: insights gained through retrograde perfusion

Repurposing rosiglitazone, a PPAR-γ agonist and oral antidiabetic, as an inhaled formulation, for the treatment of PAH

Cocktail of Superoxide Dismutase and Fasudil Encapsulated in Targeted Liposomes Slows PAH Progression at a Reduced Dosing Frequency

Serotonin passes through myoendothelial gap junctions to promote pulmonary arterial smooth muscle cell differentiation

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