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The role of lipid droplets in metabolic disease in rodents and humans

The Journal of clinical investigation, 2011-06, Vol.121 (6), p.2102-2110

2011

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Perilipin‐2 promotes obesity and progressive fatty liver disease in mice through mechanistically distinct hepatocyte and extra‐hepatocyte actions

The Journal of physiology, 2019-03, Vol.597 (6), p.1565-1584

2019

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Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome

Nature communications, 2013-09, Vol.4 (1), p.2434-2434, Article 2434

2013

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Perilipin-2-null mice are protected against diet-induced obesity, adipose inflammation, and fatty liver disease[S]

Journal of lipid research, 2013-05, Vol.54 (5), p.1346-1359

2013

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Perilipin-2 deletion promotes carbohydrate-mediated browning of white adipose tissue at ambient temperature

Journal of lipid research, 2018-08, Vol.59 (8), p.1482-1500

2018

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Perilipin-2 Modulates Lipid Absorption and Microbiome Responses in the Mouse Intestine

PloS one, 2015-07, Vol.10 (7), p.e0131944-e0131944

2015

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Dynamic regulation of hepatic lipid droplet properties by diet

PloS one, 2013-07, Vol.8 (7), p.e67631-e67631

2013

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Maternal obesity reduces milk lipid production in lactating mice by inhibiting acetyl-CoA carboxylase and impairing fatty acid synthesis

PloS one, 2014-05, Vol.9 (5), p.e98066

2014

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Dynamics and molecular determinants of cytoplasmic lipid droplet clustering and dispersion

PloS one, 2013-06, Vol.8 (6), p.e66837-e66837

2013

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Determinants of adipophilin function in milk lipid formation and secretion

Trends in endocrinology and metabolism, 2011-06, Vol.22 (6), p.211-217

2011

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An autonomous metabolic role for Spen

PLoS genetics, 2017-06, Vol.13 (6), p.e1006859-e1006859

2017

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Comparative proteomic analysis of human milk fat globules and paired membranes and mouse milk fat globules identifies core cellular systems contributing to mammary lipid trafficking and secretion

Frontiers in molecular biosciences, 2023-12, Vol.10, p.1259047-1259047

2023

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Organellar Contacts of Milk Lipid Droplets

Contact, 2020-01, Vol.3, p.251525641989722

2020

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Metabolic regulation in the lactating mammary gland: a lipid synthesizing machine

Physiological genomics, 2007-02, Vol.28 (3), p.323-336

2007

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Chronic Ethanol Consumption in Mice Alters Hepatocyte Lipid Droplet Properties

Alcoholism, clinical and experimental research, 2011-06, Vol.35 (6), p.1020-1033

2011

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Adipophilin regulates maturation of cytoplasmic lipid droplets and alveolae in differentiating mammary glands

Journal of cell science, 2011-10, Vol.124 (Pt 19), p.3247-3253

2011

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Correction: An autonomous metabolic role for Spen

PLoS genetics, 2018-03, Vol.14 (3), p.e1007266-e1007266

2018

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Impact of High-Fat Diet and Obesity on Energy Balance and Fuel Utilization During the Metabolic Challenge of Lactation

Obesity (Silver Spring, Md.), 2012-01, Vol.20 (1), p.65-75

2012

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Perilipin-2 promotes lipid droplet-plasma membrane interactions that facilitate apocrine lipid secretion in secretory epithelial cells of the mouse mammary gland

Frontiers in cell and developmental biology, 2022-09, Vol.10, p.958566

2022

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Perilipin-2 Deletion Impairs Hepatic Lipid Accumulation by Interfering with Sterol Regulatory Element-binding Protein (SREBP) Activation and Altering the Hepatic Lipidome

The Journal of biological chemistry, 2016-11, Vol.291 (46), p.24231-24246

2016

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Lipid Transport in the Lactating Mammary Gland

Journal of mammary gland biology and neoplasia, 2014-03, Vol.19 (1), p.35-42

McManaman, James L.

2014

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Milk lipid secretion: recent biomolecular aspects

Biomolecular concepts, 2012-12, Vol.3 (6), p.581-591

McManaman, James L.

2012

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Perilipin-2 modulates dietary fat-induced microbial global gene expression profiles in the mouse intestine

Microbiome, 2017-09, Vol.5 (1), p.117-117, Article 117

2017

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Cytoplasmic lipid droplet accumulation in developing mammary epithelial cells: roles of adipophilin and lipid metabolism

Journal of lipid research, 2007-07, Vol.48 (7), p.1463-1475

2007

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High-Fat Diet Causes Subfertility and Compromised Ovarian Function Independent of Obesity in Mice1

Biology of reproduction, 2016-05, Vol.94 (5)

2016

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Fundamental And Applied Biological Sciences. Psychology
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The role of lipid droplets in metabolic disease in rodents and humans

Perilipin‐2 promotes obesity and progressive fatty liver disease in mice through mechanistically distinct hepatocyte and extra‐hepatocyte actions

Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome

Perilipin-2-null mice are protected against diet-induced obesity, adipose inflammation, and fatty liver disease[S]

Perilipin-2 deletion promotes carbohydrate-mediated browning of white adipose tissue at ambient temperature

Perilipin-2 Modulates Lipid Absorption and Microbiome Responses in the Mouse Intestine

Dynamic regulation of hepatic lipid droplet properties by diet

Maternal obesity reduces milk lipid production in lactating mice by inhibiting acetyl-CoA carboxylase and impairing fatty acid synthesis

Dynamics and molecular determinants of cytoplasmic lipid droplet clustering and dispersion

Determinants of adipophilin function in milk lipid formation and secretion

An autonomous metabolic role for Spen

Comparative proteomic analysis of human milk fat globules and paired membranes and mouse milk fat globules identifies core cellular systems contributing to mammary lipid trafficking and secretion

Organellar Contacts of Milk Lipid Droplets

Metabolic regulation in the lactating mammary gland: a lipid synthesizing machine

Chronic Ethanol Consumption in Mice Alters Hepatocyte Lipid Droplet Properties

Adipophilin regulates maturation of cytoplasmic lipid droplets and alveolae in differentiating mammary glands

Correction: An autonomous metabolic role for Spen

Impact of High-Fat Diet and Obesity on Energy Balance and Fuel Utilization During the Metabolic Challenge of Lactation

Perilipin-2 promotes lipid droplet-plasma membrane interactions that facilitate apocrine lipid secretion in secretory epithelial cells of the mouse mammary gland

Perilipin-2 Deletion Impairs Hepatic Lipid Accumulation by Interfering with Sterol Regulatory Element-binding Protein (SREBP) Activation and Altering the Hepatic Lipidome

Lipid Transport in the Lactating Mammary Gland

Milk lipid secretion: recent biomolecular aspects

Perilipin-2 modulates dietary fat-induced microbial global gene expression profiles in the mouse intestine

Cytoplasmic lipid droplet accumulation in developing mammary epithelial cells: roles of adipophilin and lipid metabolism

High-Fat Diet Causes Subfertility and Compromised Ovarian Function Independent of Obesity in Mice1

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