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Nucleolar enlargement, nuclear eccentricity and altered cell body immunostaining characteristics of large-sized sensory neurons following treatment of rats with paclitaxel

Neurotoxicology (Park Forest South), 2007-11, Vol.28 (6), p.1092-1098

2007

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Oxaliplatin causes selective atrophy of a subpopulation of dorsal root ganglion neurons without inducing cell loss

Cancer chemotherapy and pharmacology, 2005-10, Vol.56 (4), p.391-399

2005

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Randomised phase II study of ASA404 combined with carboplatin and paclitaxel in previously untreated advanced non-small cell lung cancer

British journal of cancer, 2008-12, Vol.99 (12), p.2006-2012

2008

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Mechanisms of cytotoxicity and antitumor activity of gold(I) phosphine complexes: the possible role of mitochondria

Coordination chemistry reviews, 2002-10, Vol.232 (1), p.127-135

2002

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A Phase 1 Study of AS1409, a Novel Antibody-Cytokine Fusion Protein, in Patients with Malignant Melanoma or Renal Cell Carcinoma

Clinical cancer research, 2011-04, Vol.17 (7), p.1998-2005

2011

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Lobaplatin: a new antitumour platinum drug

Expert opinion on investigational drugs, 2001-01, Vol.10 (1), p.119-128

McKeage, Mark J

2001

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New-generation platinum drugs in the treatment of cisplatin-resistant cancers

Expert opinion on investigational drugs, 2005-08, Vol.14 (8), p.1033-1046

McKeage, Mark J

2005

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Comparative adverse effect profiles of platinum drugs

Drug safety, 1995-10, Vol.13 (4), p.228-244

MCKEAGE, M. J

1995

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Satraplatin activation by haemoglobin, cytochrome C and liver microsomes in vitro

Cancer chemotherapy and pharmacology, 2006-04, Vol.57 (4), p.483-490

2006

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Relationships between hydrophobicity, reactivity, accumulation and peripheral nerve toxicity of a series of platinum drugs

British journal of cancer, 2000-02, Vol.82 (4), p.966-972

2000

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Platinum neurotoxicity: clinical profiles, experimental models and neuroprotective approaches

Journal of inorganic biochemistry, 1999-10, Vol.77 (1), p.105-110

1999

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Nucleolar damage correlates with neurotoxicity induced by different platinum drugs

British journal of cancer, 2001-10, Vol.85 (8), p.1219-1225

2001

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Mass balance, excretion and metabolism of [14C] ASA404 in cancer patients in a phase I trial

Cancer chemotherapy and pharmacology, 2012-05, Vol.69 (5), p.1145-1154

2012

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Role of lipophilicity in determining cellular uptake and antitumour activity of gold phosphine complexes

Cancer chemotherapy and pharmacology, 2000, Vol.46 (5), p.343-350

2000

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Marked potentiation of the antitumour activity of chemotherapeutic drugs by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)

Cancer chemotherapy and pharmacology, 2003, Vol.51 (1), p.43-52

2003

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Gold opens mitochondrial pathways to apoptosis

British journal of pharmacology, 2002-08, Vol.136 (8), p.1081-1082

McKeage, Mark J

2002

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Rapid biotransformation of satraplatin by human red blood cells in vitro

Cancer chemotherapy and pharmacology, 2002-07, Vol.50 (1), p.9-15

2002

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Structural and solution chemistry of gold(I) and silver(I) complexes of bidentate pyridyl phosphines: selective antitumour agents

Coordination chemistry reviews, 1999-05, Vol.185, p.823-836

1999

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Preclinical antitumor evaluation of bis-acetato-ammine-dichloro-cyclohexylamine platinum(IV) : an orally active platinum drug

Cancer research (Chicago, Ill.), 1993-06, Vol.53 (11), p.2581-2586

1993

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Stereoselective peripheral sensory neurotoxicity of diaminocyclohexane platinum enantiomers related to ormaplatin and oxaliplatin

British journal of cancer, 1997-01, Vol.76 (4), p.502-510

1997

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Paclitaxel induces nucleolar enlargement in dorsal root ganglion neurons in vivo reducing oxaliplatin toxicity

British journal of cancer, 2003-06, Vol.88 (12), p.1942-1947

2003

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Phase I and pharmacokinetic study of an oral platinum complex given daily for 5 days in patients with cancer

Journal of clinical oncology, 1997-07, Vol.15 (7), p.2691-2700

1997

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Preparation, DNA binding, and in vitro cytotoxicity of a pair of enantiomeric platinum(II) complexes, [(R)- and (S)-3-aminohexahydroazepine]dichloroplatinum(II). Crystal structure of the S enantiomer

Journal of medicinal chemistry, 1997-03, Vol.40 (7), p.1090-1098

1997

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Application of liquid chromatography-mass spectrometry to monitoring plasma cyclophosphamide levels in phase I trial cancer patients

Clinical and experimental pharmacology & physiology, 2004-10, Vol.31 (10), p.677-682

2004

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Preparation, DNA Binding, and in Vitro Cytotoxicity of a Pair of Enantiomeric Platinum(II) Complexes, [(R)- and (S)-3-Aminohexahydroazepine]dichloro- platinum(II). Crystal Structure of the S Enantiomer

Journal of medicinal chemistry, 1997-03, Vol.40 (7), p.1090-1098

1997

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Nucleolar enlargement, nuclear eccentricity and altered cell body immunostaining characteristics of large-sized sensory neurons following treatment of rats with paclitaxel

Oxaliplatin causes selective atrophy of a subpopulation of dorsal root ganglion neurons without inducing cell loss

Randomised phase II study of ASA404 combined with carboplatin and paclitaxel in previously untreated advanced non-small cell lung cancer

Mechanisms of cytotoxicity and antitumor activity of gold(I) phosphine complexes: the possible role of mitochondria

A Phase 1 Study of AS1409, a Novel Antibody-Cytokine Fusion Protein, in Patients with Malignant Melanoma or Renal Cell Carcinoma

Lobaplatin: a new antitumour platinum drug

New-generation platinum drugs in the treatment of cisplatin-resistant cancers

Comparative adverse effect profiles of platinum drugs

Satraplatin activation by haemoglobin, cytochrome C and liver microsomes in vitro

Relationships between hydrophobicity, reactivity, accumulation and peripheral nerve toxicity of a series of platinum drugs

Platinum neurotoxicity: clinical profiles, experimental models and neuroprotective approaches

Nucleolar damage correlates with neurotoxicity induced by different platinum drugs

Mass balance, excretion and metabolism of [14C] ASA404 in cancer patients in a phase I trial

Role of lipophilicity in determining cellular uptake and antitumour activity of gold phosphine complexes

Marked potentiation of the antitumour activity of chemotherapeutic drugs by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA)

Gold opens mitochondrial pathways to apoptosis

Rapid biotransformation of satraplatin by human red blood cells in vitro

Structural and solution chemistry of gold(I) and silver(I) complexes of bidentate pyridyl phosphines: selective antitumour agents

Preclinical antitumor evaluation of bis-acetato-ammine-dichloro-cyclohexylamine platinum(IV) : an orally active platinum drug

Stereoselective peripheral sensory neurotoxicity of diaminocyclohexane platinum enantiomers related to ormaplatin and oxaliplatin

Paclitaxel induces nucleolar enlargement in dorsal root ganglion neurons in vivo reducing oxaliplatin toxicity

Phase I and pharmacokinetic study of an oral platinum complex given daily for 5 days in patients with cancer

Preparation, DNA binding, and in vitro cytotoxicity of a pair of enantiomeric platinum(II) complexes, [(R)- and (S)-3-aminohexahydroazepine]dichloroplatinum(II). Crystal structure of the S enantiomer

Application of liquid chromatography-mass spectrometry to monitoring plasma cyclophosphamide levels in phase I trial cancer patients

Preparation, DNA Binding, and in Vitro Cytotoxicity of a Pair of Enantiomeric Platinum(II) Complexes, [(R)- and (S)-3-Aminohexahydroazepine]dichloro- platinum(II). Crystal Structure of the S Enantiomer

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