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Strategies to Mitigate the Bioactivation of 2-Anilino-7-Aryl-Pyrrolo[2,1-f][1,2,4]triazines: Identification of Orally Bioavailable, Efficacious ALK Inhibitors

Journal of medicinal chemistry, 2012-01, Vol.55 (1), p.115-125

2012

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Discovery of 7-arylsulfonyl-1,2,3,4, 4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridines: Identification of a potent and selective 5-HT6 receptor antagonist showing activity in rat social recognition test

Bioorganic & medicinal chemistry letters, 2012-02, Vol.22 (3), p.1421-1426

2012

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Synthesis and evaluation of quinoxalinones as HIV-1 reverse transcriptase inhibitors

Bioorganic & medicinal chemistry letters, 2000-08, Vol.10 (15), p.1729-1731

2000

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Cyclic HIV Protease Inhibitors: Synthesis, Conformational Analysis, P2/P2‘ Structure−Activity Relationship, and Molecular Recognition of Cyclic Ureas

Journal of medicinal chemistry, 1996-08, Vol.39 (18), p.3514-3525

1996

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Pyrazolone-based anaplastic lymphoma kinase (ALK) inhibitors: Control of selectivity by a benzyloxy group

Bioorganic & medicinal chemistry letters, 2011-12, Vol.21 (24), p.7261-7264

2011

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Fused bicyclic derivatives of 2,4-diaminopyrimidine as c-Met inhibitors

Bioorganic & medicinal chemistry letters, 2011-01, Vol.21 (1), p.164-167

2011

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Synthesis and evaluation of novel quinolinones as HIV-1 reverse transcriptase inhibitors

Bioorganic & medicinal chemistry letters, 2001-07, Vol.11 (14), p.1943-1945

2001

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Synthesis and evaluation of analogs of Efavirenz (SUSTIVA TM) as HIV-1 reverse transcriptase inhibitors

Bioorganic & medicinal chemistry letters, 1999-10, Vol.9 (19), p.2805-2810

1999

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Synthesis and evaluation of benzoxazinones as HIV-1 reverse transcriptase inhibitors. Analogs of Efavirenz (SUSTIVA TM)

Bioorganic & medicinal chemistry letters, 1999-11, Vol.9 (22), p.3221-3224

1999

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Unsymmetrical cyclic ureas as HIV-1 protease inhibitors: Novel biaryl indazoles as P2/P2′ substituents

Bioorganic & medicinal chemistry letters, 1999-11, Vol.9 (22), p.3217-3220

1999

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The synthesis of symmetrical and unsymmetrical P1/P1′ cyclic ureas as HIV protease inhibitors

Bioorganic & medicinal chemistry letters, 1998-05, Vol.8 (9), p.1077-1082

1998

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Functionalized aliphatic P2/P2′ analogs of HIV-1 protease inhibitor DMP323

Bioorganic & medicinal chemistry letters, 1997-06, Vol.7 (11), p.1365-1370

1997

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Inhibition of cartilage degradation by isothiazoloquinolinones

Bioorganic & medicinal chemistry letters, 1994-03, Vol.4 (6), p.843-846

1994

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Plato at Syracuse: Essays on Plato in Western Greece with a new translation of the Seventh Letter by Jonah Radding

2019

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ChemInform Abstract: Synthesis and Evaluation of Novel Quinolinones as HIV-1 Reverse Transcriptase Inhibitors

ChemInform, 2001-11, Vol.32 (45), p.no-no

2001

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ChemInform Abstract: Synthesis and Evaluation of Quinoxalinones as HIV-1 Reverse Transcriptase Inhibitors

ChemInform, 2000-11, Vol.31 (45), p.no-no

2000

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ChemInform Abstract: Synthesis and Evaluation of Benzoxazinones as HIV-1 Reverse Transcriptase Inhibitors. Analogues of Efavirenz (Sustiva)

ChemInform, 2000-02, Vol.31 (8), p.no-no

2000

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Chronic Loss of CA2 Transmission Leads to Hippocampal Hyperexcitability

Neuron (Cambridge, Mass.), 2017-05, Vol.94 (3), p.642-655.e9

2017

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Biocompatible Semiconductor Quantum Dots as Cancer Imaging Agents

Advanced materials (Weinheim), 2018-05, Vol.30 (18), p.e1706356-n/a

2018

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Overcoming barriers to patient adherence: the case for developing innovative drug delivery systems

Nature reviews. Drug discovery, 2023-05, Vol.22 (5), p.387-409

2023

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ChemInform Abstract: Unsymmetrical Cyclic Ureas as HIV-1 Protease Inhibitors: Novel Biaryl Indazoles as P2/P2′ Substituents

ChemInform, 2000-02, Vol.31 (8), p.no-no

2000

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Layer-by-Layer Encapsulation of Probiotics for Delivery to the Microbiome

Advanced materials (Weinheim), 2016-11, Vol.28 (43), p.9486-9490

2016

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A hypothalamic novelty signal modulates hippocampal memory

Nature (London), 2020-10, Vol.586 (7828), p.270-274

2020

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Postanalytical tools improve performance of newborn screening by tandem mass spectrometry

Genetics in medicine, 2014-12, Vol.16 (12), p.889-895

2014

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Fabrication of fillable microparticles and other complex 3D microstructures

Science (American Association for the Advancement of Science), 2017-09, Vol.357 (6356), p.1138-1142

2017

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Strategies to Mitigate the Bioactivation of 2-Anilino-7-Aryl-Pyrrolo[2,1-f][1,2,4]triazines: Identification of Orally Bioavailable, Efficacious ALK Inhibitors

Discovery of 7-arylsulfonyl-1,2,3,4, 4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridines: Identification of a potent and selective 5-HT6 receptor antagonist showing activity in rat social recognition test

Synthesis and evaluation of quinoxalinones as HIV-1 reverse transcriptase inhibitors

Cyclic HIV Protease Inhibitors: Synthesis, Conformational Analysis, P2/P2‘ Structure−Activity Relationship, and Molecular Recognition of Cyclic Ureas

Pyrazolone-based anaplastic lymphoma kinase (ALK) inhibitors: Control of selectivity by a benzyloxy group

Fused bicyclic derivatives of 2,4-diaminopyrimidine as c-Met inhibitors

Synthesis and evaluation of novel quinolinones as HIV-1 reverse transcriptase inhibitors

Synthesis and evaluation of analogs of Efavirenz (SUSTIVA TM) as HIV-1 reverse transcriptase inhibitors

Synthesis and evaluation of benzoxazinones as HIV-1 reverse transcriptase inhibitors. Analogs of Efavirenz (SUSTIVA TM)

Unsymmetrical cyclic ureas as HIV-1 protease inhibitors: Novel biaryl indazoles as P2/P2′ substituents

The synthesis of symmetrical and unsymmetrical P1/P1′ cyclic ureas as HIV protease inhibitors

Functionalized aliphatic P2/P2′ analogs of HIV-1 protease inhibitor DMP323

Inhibition of cartilage degradation by isothiazoloquinolinones

Plato at Syracuse: Essays on Plato in Western Greece with a new translation of the Seventh Letter by Jonah Radding

ChemInform Abstract: Synthesis and Evaluation of Novel Quinolinones as HIV-1 Reverse Transcriptase Inhibitors

ChemInform Abstract: Synthesis and Evaluation of Quinoxalinones as HIV-1 Reverse Transcriptase Inhibitors

ChemInform Abstract: Synthesis and Evaluation of Benzoxazinones as HIV-1 Reverse Transcriptase Inhibitors. Analogues of Efavirenz (Sustiva)

Chronic Loss of CA2 Transmission Leads to Hippocampal Hyperexcitability

Biocompatible Semiconductor Quantum Dots as Cancer Imaging Agents

Overcoming barriers to patient adherence: the case for developing innovative drug delivery systems

ChemInform Abstract: Unsymmetrical Cyclic Ureas as HIV-1 Protease Inhibitors: Novel Biaryl Indazoles as P2/P2′ Substituents

Layer-by-Layer Encapsulation of Probiotics for Delivery to the Microbiome

A hypothalamic novelty signal modulates hippocampal memory

Postanalytical tools improve performance of newborn screening by tandem mass spectrometry

Fabrication of fillable microparticles and other complex 3D microstructures

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