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Perspective: Quality Versus Quantity; Is It Important to Assess the Role of Enhancers in Complex Disease from an In Vivo Perspective?

International journal of molecular sciences, 2020-10, Vol.21 (21), p.7856

2020

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An Efficient Method for the In Vitro Production of Azol(in)e-Based Cyclic Peptides

Angewandte Chemie International Edition, 2014-12, Vol.53 (51), p.14171-14174

International ed. in English, 2014

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Isolation and anti-HIV-1 integrase activity of lentzeosides A–F from extremotolerant lentzea sp. H45, a strain isolated from a high-altitude Atacama Desert soil

Journal of antibiotics, 2017-04, Vol.70 (4), p.448-453

2017

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Context-dependant enhancers as a reservoir of functional polymorphisms and epigenetic markers linked to alcohol use disorders and comorbidities

Addiction neuroscience, 2022-06, Vol.2, p.100014-None, Article 100014

2022

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Mechanism of Enzymatic Fluorination in Streptomyces cattleya

Journal of the American Chemical Society, 2007-11, Vol.129 (47), p.14597-14604

2007

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Gated rotation mechanism of site-specific recombination by ΦC31 integrase

Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (48), p.19661-19666

2012

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The Fluorinase from Streptomyces cattleya Is Also a Chlorinase

Angewandte Chemie International Edition, 2006-01, Vol.45 (5), p.759-762

2006

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An ancient polymorphic regulatory region within the BDNF gene associated with obesity modulates anxiety-like behaviour in mice and humans

Molecular psychiatry, 2024-03, Vol.29 (3), p.660-670

2024

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Disease‐associated polymorphisms within the conserved ECR1 enhancer differentially regulate the tissue‐specific activity of the cannabinoid‐1 receptor gene promoter; implications for cannabinoid pharmacogenetics

Human mutation, 2020-01, Vol.41 (1), p.291-298

2020

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CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake

Molecular psychiatry, 2021-06, Vol.26 (6), p.2263-2276

2021

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A phage protein that binds φC31 integrase to switch its directionality

Molecular microbiology, 2011-06, Vol.80 (6), p.1450-1463

2011

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Site-specific recombination by φC31 integrase and other large serine recombinases

Biochemical Society transactions, 2010-04, Vol.38 (2), p.388-394

2010

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Accurate quantification of modified cyclic peptides without the need for authentic standards

Tetrahedron, 2016-12, Vol.72 (52), p.8603-8609

2016

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A Blind Test of Computational Technique for Predicting the Likelihood of Peptide Sequences to Cyclize

The journal of physical chemistry letters, 2017-05, Vol.8 (10), p.2310-2315

2017

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Zinc is essential for high-affinity DNA binding and recombinase activity of ΦC31 integrase

Nucleic acids research, 2011-08, Vol.39 (14), p.6137-6147

2011

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Characterization and crystal structure of Escherichia coli KDPGal aldolase

Bioorganic & medicinal chemistry, 2008-01, Vol.16 (2), p.710-720

2008

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Substrate specificity in enzymatic fluorination. The fluorinase from Streptomyces cattleya accepts 2'-deoxyadenosine substrates

Organic & biomolecular chemistry, 2006-01, Vol.4 (8), p.1458-1460

2006

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Mechanism of Enzymatic Fluorination in Streptomyces c attleya

Journal of the American Chemical Society, 2007-11, Vol.129 (47), p.14597-14604

2007

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An Efficient Method for the In Vitro Production of Azol(in)e-Based Cyclic Peptides

Angewandte Chemie, 2014-12, Vol.126 (51), p.14395-14398

2014

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A phage protein that binds [straight phi]C31 integrase to switch its directionality

Molecular microbiology, 2011-06, Vol.80 (6), p.1450

2011

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Gated rotation mechanism of site-specific recombination by [phi]C31 integrase

Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (48), p.19661

2012

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Overexpression, purification, crystallization and data collection of Sulfolobus solfataricus Sso6206, a novel highly conserved protein

Acta crystallographica. Section F, Structural biology and crystallization communications, 2006-03, Vol.62 (3), p.228-230

2006

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DNA binding and synapsis by the large C-terminal domain of C31 integrase

Nucleic acids research, 2009-08, Vol.37 (14), p.4764-4773

2009

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DNA binding and synapsis by the large C-terminal domain of phiC31 integrase

Nucleic acids research, 2009-08, Vol.37 (14), p.4764

2009

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Characterization and crystal structure of Escherichia coli KDPGal aldolase

Bioorganic & medicinal chemistry, 2006-01, Vol.14 (9), p.3002-3010

2006

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Perspective: Quality Versus Quantity; Is It Important to Assess the Role of Enhancers in Complex Disease from an In Vivo Perspective?

An Efficient Method for the In Vitro Production of Azol(in)e-Based Cyclic Peptides

Isolation and anti-HIV-1 integrase activity of lentzeosides A–F from extremotolerant lentzea sp. H45, a strain isolated from a high-altitude Atacama Desert soil

Context-dependant enhancers as a reservoir of functional polymorphisms and epigenetic markers linked to alcohol use disorders and comorbidities

Mechanism of Enzymatic Fluorination in Streptomyces cattleya

Gated rotation mechanism of site-specific recombination by ΦC31 integrase

The Fluorinase from Streptomyces cattleya Is Also a Chlorinase

An ancient polymorphic regulatory region within the BDNF gene associated with obesity modulates anxiety-like behaviour in mice and humans

Disease‐associated polymorphisms within the conserved ECR1 enhancer differentially regulate the tissue‐specific activity of the cannabinoid‐1 receptor gene promoter; implications for cannabinoid pharmacogenetics

CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests a role in male anxiety and ethanol intake

A phage protein that binds φC31 integrase to switch its directionality

Site-specific recombination by φC31 integrase and other large serine recombinases

Accurate quantification of modified cyclic peptides without the need for authentic standards

A Blind Test of Computational Technique for Predicting the Likelihood of Peptide Sequences to Cyclize

Zinc is essential for high-affinity DNA binding and recombinase activity of ΦC31 integrase

Characterization and crystal structure of Escherichia coli KDPGal aldolase

Substrate specificity in enzymatic fluorination. The fluorinase from Streptomyces cattleya accepts 2'-deoxyadenosine substrates

Mechanism of Enzymatic Fluorination in Streptomyces c attleya

An Efficient Method for the In Vitro Production of Azol(in)e-Based Cyclic Peptides

A phage protein that binds [straight phi]C31 integrase to switch its directionality

Gated rotation mechanism of site-specific recombination by [phi]C31 integrase

Overexpression, purification, crystallization and data collection of Sulfolobus solfataricus Sso6206, a novel highly conserved protein

DNA binding and synapsis by the large C-terminal domain of C31 integrase

DNA binding and synapsis by the large C-terminal domain of phiC31 integrase

Characterization and crystal structure of Escherichia coli KDPGal aldolase

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