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Interleukin-6: obstacles to targeting a complex cytokine in critical illness

The lancet respiratory medicine, 2021-06, Vol.9 (6), p.643-654

2021

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Dysregulated plasma lipid mediator profiles in critically ill COVID-19 patients

PloS one, 2021-08, Vol.16 (8), p.e0256226-e0256226

2021

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Intravenous augmentation treatment and lung density in severe α1 antitrypsin deficiency (RAPID): a randomised, double-blind, placebo-controlled trial

The Lancet (British edition), 2015-07, Vol.386 (9991), p.360-368

2015

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A neutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy

Blood, 2014-08, Vol.124 (7), p.999-1009

2014

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Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing

Cell reports (Cambridge), 2018-03, Vol.22 (11), p.2937-2950

2018

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Granzyme B-Dependent Proteolysis Acts as a Switch to Enhance the Proinflammatory Activity of IL-1α

Molecular cell, 2011-10, Vol.44 (2), p.265-278

2011

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A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19

EBioMedicine, 2020-11, Vol.61, p.103026-103026, Article 103026

2020

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Proteases and antiproteases in chronic neutrophilic lung disease – relevance to drug discovery

British journal of pharmacology, 2009-10, Vol.158 (4), p.1048-1058

2009

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Diagnosing α1-antitrypsin deficiency: how to improve the current algorithm

European respiratory review, 2015-03, Vol.24 (135), p.52-57

McElvaney, Noel G

2015

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Anaerobic bacteria cultured from cystic fibrosis airways correlate to milder disease: a multisite study

The European respiratory journal, 2018-07, Vol.52 (1), p.1800242-1800242

2018

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Sex differences in airway disease: estrogen and airway surface liquid dynamics

Biology of sex differences, 2024-07, Vol.15 (1), p.56-30, Article 56

2024

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A Review of Alpha-1 Antitrypsin Binding Partners for Immune Regulation and Potential Therapeutic Application

International journal of molecular sciences, 2022-02, Vol.23 (5), p.2441

2022

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MicroRNAs in inflammatory lung disease--master regulators or target practice?

Respiratory research, 2010-10, Vol.11 (1), p.148-148, Article 148

2010

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The Role of Short-Chain Fatty Acids, Produced by Anaerobic Bacteria, in the Cystic Fibrosis Airway

American journal of respiratory and critical care medicine, 2015-12, Vol.192 (11), p.1314-1324

2015

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Clarification of the Risk of Chronic Obstructive Pulmonary Disease in α1-Antitrypsin Deficiency PiMZ Heterozygotes

American journal of respiratory and critical care medicine, 2014-02, Vol.189 (4), p.419-427

2014

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Altered Serum Alpha1-Antitrypsin Protease Inhibition before and after Clinical Hematopoietic Stem Cell Transplantation: Association with Risk for Non-Relapse Mortality

International journal of molecular sciences, 2023-12, Vol.25 (1), p.422

2023

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Effect of Estrogen on Pseudomonas Mucoidy and Exacerbations in Cystic Fibrosis

The New England journal of medicine, 2012-05, Vol.366 (21), p.1978-1986

2012

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Targeting of Glycosaminoglycans in Genetic and Inflammatory Airway Disease

International journal of molecular sciences, 2022-06, Vol.23 (12), p.6400

2022

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Prone positioning improves oxygenation and lung recruitment in patients with SARS-CoV-2 acute respiratory distress syndrome; a single centre cohort study of 20 consecutive patients

BMC research notes, 2021-01, Vol.14 (1), p.20-20, Article 20

2021

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miR-126 Is Downregulated in Cystic Fibrosis Airway Epithelial Cells and Regulates TOM1 Expression

The Journal of immunology (1950), 2010-02, Vol.184 (4), p.1702-1709

2010

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Pitfalls and caveats in α1-antitrypsin deficiency testing: a guide for clinicians

The lancet respiratory medicine, 2019-12, Vol.7 (12), p.1059-1067

2019

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miR-199a-5p Silencing Regulates the Unfolded Protein Response in Chronic Obstructive Pulmonary Disease and α1-Antitrypsin Deficiency

American journal of respiratory and critical care medicine, 2014-02, Vol.189 (3), p.263-273

2014

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The European Alpha-1 Research Collaboration (EARCO): a new ERS Clinical Research Collaboration to promote research in alpha-1 antitrypsin deficiency

The European respiratory journal, 2019-02, Vol.53 (2), p.1900138

2019

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Long noncoding RNA are aberrantly expressed in vivo in the cystic fibrosis bronchial epithelium

The international journal of biochemistry & cell biology, 2014-07, Vol.52, p.184-191

2014

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Interleukin-6: obstacles to targeting a complex cytokine in critical illness

Dysregulated plasma lipid mediator profiles in critically ill COVID-19 patients

Intravenous augmentation treatment and lung density in severe α1 antitrypsin deficiency (RAPID): a randomised, double-blind, placebo-controlled trial

A neutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy

Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing

Granzyme B-Dependent Proteolysis Acts as a Switch to Enhance the Proinflammatory Activity of IL-1α

A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19

Proteases and antiproteases in chronic neutrophilic lung disease – relevance to drug discovery

Diagnosing α1-antitrypsin deficiency: how to improve the current algorithm

Anaerobic bacteria cultured from cystic fibrosis airways correlate to milder disease: a multisite study

Sex differences in airway disease: estrogen and airway surface liquid dynamics

A Review of Alpha-1 Antitrypsin Binding Partners for Immune Regulation and Potential Therapeutic Application

MicroRNAs in inflammatory lung disease--master regulators or target practice?

The Role of Short-Chain Fatty Acids, Produced by Anaerobic Bacteria, in the Cystic Fibrosis Airway

Clarification of the Risk of Chronic Obstructive Pulmonary Disease in α1-Antitrypsin Deficiency PiMZ Heterozygotes

Altered Serum Alpha1-Antitrypsin Protease Inhibition before and after Clinical Hematopoietic Stem Cell Transplantation: Association with Risk for Non-Relapse Mortality

Effect of Estrogen on Pseudomonas Mucoidy and Exacerbations in Cystic Fibrosis

Targeting of Glycosaminoglycans in Genetic and Inflammatory Airway Disease

Prone positioning improves oxygenation and lung recruitment in patients with SARS-CoV-2 acute respiratory distress syndrome; a single centre cohort study of 20 consecutive patients

miR-126 Is Downregulated in Cystic Fibrosis Airway Epithelial Cells and Regulates TOM1 Expression

Pitfalls and caveats in α1-antitrypsin deficiency testing: a guide for clinicians

Long-term efficacy and safety of α1 proteinase inhibitor treatment for emphysema caused by severe α1 antitrypsin deficiency: an open-label extension trial (RAPID-OLE)

miR-199a-5p Silencing Regulates the Unfolded Protein Response in Chronic Obstructive Pulmonary Disease and α1-Antitrypsin Deficiency

The European Alpha-1 Research Collaboration (EARCO): a new ERS Clinical Research Collaboration to promote research in alpha-1 antitrypsin deficiency

Long noncoding RNA are aberrantly expressed in vivo in the cystic fibrosis bronchial epithelium

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