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Increased Akt Signaling Resulting from the Loss of Androgen Responsiveness in Prostate Cancer

Current medicinal chemistry, 2012-12, Vol.20 (1), p.144-157

2012

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Roles of the Ras Raf MEK ERK pathway in leukemia therapy

Leukemia, 2011-07, Vol.25 (7), p.1080-1094

2011

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Targeting the PI3K/Akt/mTOR signaling pathway in B-precursor acute lymphoblastic leukemia and its therapeutic potential

Leukemia, 2014-04, Vol.28 (4), p.739-748

2014

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STAT transcription factors in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention

Leukemia, 2014-02, Vol.28 (2), p.248-257

2014

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Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K PTEN Akt mTOR pathway

Leukemia, 2011-07, Vol.25 (7), p.1064-1079

2011

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Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention

Leukemia, 2014-01, Vol.28 (1), p.15-33

2014

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Contributions of the Raf MEK ERK, PI3K PTEN Akt mTOR and Jak STAT pathways to leukemia

Leukemia, 2008-04, Vol.22 (4), p.686-707

2008

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Targeting survival cascades induced by activation of Ras Raf MEK ERK, PI3K PTEN Akt mTOR and Jak STAT pathways for effective leukemia therapy

Leukemia, 2008-04, Vol.22 (4), p.708-722

2008

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Targeting the leukemic stem cell: the Holy Grail of leukemia therapy

Leukemia, 2009-01, Vol.23 (1), p.25-42

2009

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Cytotoxic activity of the casein kinase 2 inhibitor CX-4945 against T-cell acute lymphoblastic leukemia: targeting the unfolded protein response signaling

Leukemia, 2014-03, Vol.28 (3), p.543-553

2014

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Cytotoxic activity of the novel Akt inhibitor, MK-2206, in T-cell acute lymphoblastic leukemia

Leukemia, 2012-11, Vol.26 (11), p.2336-2342

2012

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Multidrug resistance-associated protein 1 expression is under the control of the phosphoinositide 3 kinase Akt signal transduction network in human acute myelogenous leukemia blasts

Leukemia, 2007-03, Vol.21 (3), p.427-438

2007

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Activity of the pan-class I phosphoinositide 3-kinase inhibitor NVP-BKM120 in T-cell acute lymphoblastic leukemia

Leukemia, 2014-06, Vol.28 (6), p.1196-1206

2014

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Targeted inhibition of mTORC1 and mTORC2 by active-site mTOR inhibitors has cytotoxic effects in T-cell acute lymphoblastic leukemia

Leukemia, 2011-05, Vol.25 (5), p.781-791

2011

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AMP-dependent kinase mammalian target of rapamycin complex 1 signaling in T-cell acute lymphoblastic leukemia: therapeutic implications

Leukemia, 2012-01, Vol.26 (1), p.91-100

2012

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Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors

Oncogene, 2008-07, Vol.27 (29), p.4086-4095

2008

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Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor perifosine in acute myelogenous leukemia cells

Leukemia, 2008-01, Vol.22 (1), p.147-160

2008

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Systematic analysis of GSK-3 signaling pathways in aging of cerebral tissue

Advances in biological regulation, 2018-08, Vol.69, p.35-42

2018

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Involvement of p53 and Raf MEK ERK pathways in hematopoietic drug resistance

Leukemia, 2008-11, Vol.22 (11), p.2080-2090

2008

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Targeting the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin module for acute myelogenous leukemia therapy: from bench to bedside

Current medicinal chemistry, 2007-08, Vol.14 (19), p.2009-2023

2007

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Mutations in the catalytic subunit of class IA PI3K confer leukemogenic potential to hematopoietic cells

Oncogene, 2008-07, Vol.27 (29), p.4096-4106

2008

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Erucylphosphohomocholine, the first intravenously applicable alkylphosphocholine, is cytotoxic to acute myelogenous leukemia cells through JNK- and PP2A-dependent mechanisms

Leukemia, 2010-04, Vol.24 (4), p.687-698

2010

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Regulation of the mitogen-activated protein kinase kinase -1 by [NAD.sup+]-dependent deacetylases

Oncogene, 2015-02, p.798

2015

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Spotlight Imatinib: a model for signal transduction inhibitors

Leukemia, 2002-07, Vol.16 (7), p.1205-1206

2002

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The Raf/MEK/ERK signal transduction cascade as a target for chemotherapeutic intervention in leukemia

Leukemia, 2002-04, Vol.16 (4), p.486-507

2002

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Increased Akt Signaling Resulting from the Loss of Androgen Responsiveness in Prostate Cancer

Roles of the Ras Raf MEK ERK pathway in leukemia therapy

Targeting the PI3K/Akt/mTOR signaling pathway in B-precursor acute lymphoblastic leukemia and its therapeutic potential

STAT transcription factors in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention

Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K PTEN Akt mTOR pathway

Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention

Contributions of the Raf MEK ERK, PI3K PTEN Akt mTOR and Jak STAT pathways to leukemia

Targeting survival cascades induced by activation of Ras Raf MEK ERK, PI3K PTEN Akt mTOR and Jak STAT pathways for effective leukemia therapy

Targeting the leukemic stem cell: the Holy Grail of leukemia therapy

Cytotoxic activity of the casein kinase 2 inhibitor CX-4945 against T-cell acute lymphoblastic leukemia: targeting the unfolded protein response signaling

Cytotoxic activity of the novel Akt inhibitor, MK-2206, in T-cell acute lymphoblastic leukemia

Multidrug resistance-associated protein 1 expression is under the control of the phosphoinositide 3 kinase Akt signal transduction network in human acute myelogenous leukemia blasts

Activity of the pan-class I phosphoinositide 3-kinase inhibitor NVP-BKM120 in T-cell acute lymphoblastic leukemia

Targeted inhibition of mTORC1 and mTORC2 by active-site mTOR inhibitors has cytotoxic effects in T-cell acute lymphoblastic leukemia

AMP-dependent kinase mammalian target of rapamycin complex 1 signaling in T-cell acute lymphoblastic leukemia: therapeutic implications

Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors

Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor perifosine in acute myelogenous leukemia cells

Systematic analysis of GSK-3 signaling pathways in aging of cerebral tissue

Involvement of p53 and Raf MEK ERK pathways in hematopoietic drug resistance

Targeting the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin module for acute myelogenous leukemia therapy: from bench to bedside

Mutations in the catalytic subunit of class IA PI3K confer leukemogenic potential to hematopoietic cells

Erucylphosphohomocholine, the first intravenously applicable alkylphosphocholine, is cytotoxic to acute myelogenous leukemia cells through JNK- and PP2A-dependent mechanisms

Regulation of the mitogen-activated protein kinase kinase -1 by [NAD.sup+]-dependent deacetylases

Spotlight Imatinib: a model for signal transduction inhibitors

The Raf/MEK/ERK signal transduction cascade as a target for chemotherapeutic intervention in leukemia

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