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Investigating protein-excipient interactions of a multivalent VHH therapeutic protein using NMR spectroscopy

mAbs, 2022, Vol.14 (1), p.2124902-2124902

2022

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Discovery of Selective RNA-Binding Small Molecules by Affinity-Selection Mass Spectrometry

ACS chemical biology, 2018-03, Vol.13 (3), p.820-831

2018

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Quantification of natural abundance NMR data differentiates the solution behavior of monoclonal antibodies and their fragments

mAbs, 2021-01, Vol.13 (1), p.1978132-1978132

2021

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Insulin purification-Innovation continuum via synthesis of fundamentals, technology, and modeling

Biotechnology and bioengineering, 2023-05

2023

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Diffusion Profiling of Therapeutic Proteins by Using Solution NMR Spectroscopy

Chembiochem : a European journal of chemical biology, 2019-04, Vol.20 (7), p.896-899

2019

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Investigating protein-excipient interactions of a multivalent V HH therapeutic protein using NMR spectroscopy

mAbs, 2022-12, Vol.14 (1), p.2124902

2022

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Spatial Localization of Ligand Binding Sites from Electron Current Density Surfaces Calculated from NMR Chemical Shift Perturbations

Journal of the American Chemical Society, 2002-10, Vol.124 (39), p.11758-11763

2002

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Profiling Insulin Oligomeric States by 1H NMR Spectroscopy for Formulation Development of Ultra-Rapid-Acting Insulin

Journal of pharmaceutical sciences, 2020-01, Vol.109 (1), p.922-926

2020

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Mechanistic insights on novel small molecule allosteric activators of cGMP-dependent protein kinase PKG1α

The Journal of biological chemistry, 2022-09, Vol.298 (9), p.102284-102284, Article 102284

2022

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NMR Data‐Driven Docking of HDM2‐Inhibitor Complexes

Chembiochem : a European journal of chemical biology, 2022-03, Vol.23 (6), p.e202100570-n/a

2022

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Flexible Lid to the p53-Binding Domain of Human Mdm2: Implications for p53 Regulation

Proceedings of the National Academy of Sciences - PNAS, 2003-02, Vol.100 (4), p.1645-1648

2003

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Identification of preferred multimodal ligand‐binding regions on IgG1 FC using nuclear magnetic resonance and molecular dynamics simulations

Biotechnology and bioengineering, 2021-02, Vol.118 (2), p.809-822

2021

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Probing IgG1 FC–Multimodal Nanoparticle Interactions: A Combined Nuclear Magnetic Resonance and Molecular Dynamics Simulations Approach

Langmuir, 2021-10, Vol.37 (41), p.12188-12203

2021

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Structures of Protein−Protein Complexes Are Docked Using Only NMR Restraints from Residual Dipolar Coupling and Chemical Shift Perturbations

Journal of the American Chemical Society, 2002-03, Vol.124 (10), p.2104-2105

2002

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NMR Assessment of Therapeutic Peptides and Proteins: Correlations That Reveal Interactions and Motions

Chembiochem : a European journal of chemical biology, 2020-02, Vol.21 (3), p.315-319

2020

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Identification of preferred multimodal ligand-binding regions on IgG1 F C using nuclear magnetic resonance and molecular dynamics simulations

Biotechnology and bioengineering, 2021-02, Vol.118 (2), p.809-822

2021

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NMR Binding and Functional Assays for Detecting Inhibitors of S. aureus MnaA

Journal of biomolecular screening, 2016-07, Vol.21 (6), p.579-589

2016

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Screening of Protein Kinases by ATP-STD NMR Spectroscopy

Journal of the American Chemical Society, 2005-06, Vol.127 (22), p.7978-7979

2005

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Discovery and Hit-to-Lead Optimization of Non-ATP Competitive MK2 (MAPKAPK2) Inhibitors

ACS medicinal chemistry letters, 2011-08, Vol.2 (8), p.632-637

2011

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Non-Peptidic Small-Molecule Inhibitors of the Single-Chain Hepatitis C Virus NS3 Protease/NS4A Cofactor Complex Discovered by Structure-Based NMR Screening

Journal of medicinal chemistry, 2004-05, Vol.47 (10), p.2486-2498

2004

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Cover Feature: Diffusion Profiling of Therapeutic Proteins by Using Solution NMR Spectroscopy (ChemBioChem 7/2019)

Chembiochem : a European journal of chemical biology, 2019-04, Vol.20 (7), p.859-859

2019

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Probing IgG1 F C –Multimodal Nanoparticle Interactions: A Combined Nuclear Magnetic Resonance and Molecular Dynamics Simulations Approach

Langmuir, 2021-10, Vol.37 (41), p.12188-12203

2021

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Identification of preferred multimodal ligand‐binding regions on IgG1 F C using nuclear magnetic resonance and molecular dynamics simulations

Biotechnology and bioengineering, 2020-11, Vol.118 (2)

2020

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Investigating protein-excipient interactions of a multivalent VHH therapeutic protein using NMR spectroscopy

Discovery of Selective RNA-Binding Small Molecules by Affinity-Selection Mass Spectrometry

Quantification of natural abundance NMR data differentiates the solution behavior of monoclonal antibodies and their fragments

Insulin purification-Innovation continuum via synthesis of fundamentals, technology, and modeling

Diffusion Profiling of Therapeutic Proteins by Using Solution NMR Spectroscopy

Investigating protein-excipient interactions of a multivalent V HH therapeutic protein using NMR spectroscopy

Spatial Localization of Ligand Binding Sites from Electron Current Density Surfaces Calculated from NMR Chemical Shift Perturbations

Profiling Insulin Oligomeric States by 1H NMR Spectroscopy for Formulation Development of Ultra-Rapid-Acting Insulin

Mechanistic insights on novel small molecule allosteric activators of cGMP-dependent protein kinase PKG1α

NMR Data‐Driven Docking of HDM2‐Inhibitor Complexes

Flexible Lid to the p53-Binding Domain of Human Mdm2: Implications for p53 Regulation

Identification of preferred multimodal ligand‐binding regions on IgG1 FC using nuclear magnetic resonance and molecular dynamics simulations

Probing IgG1 FC–Multimodal Nanoparticle Interactions: A Combined Nuclear Magnetic Resonance and Molecular Dynamics Simulations Approach

Structures of Protein−Protein Complexes Are Docked Using Only NMR Restraints from Residual Dipolar Coupling and Chemical Shift Perturbations

NMR Assessment of Therapeutic Peptides and Proteins: Correlations That Reveal Interactions and Motions

Discovery of Insulin Receptor Partial Agonists MK-5160 and MK-1092 as Novel Basal Insulins with Potential to Improve Therapeutic Index

Identification of preferred multimodal ligand-binding regions on IgG1 F C using nuclear magnetic resonance and molecular dynamics simulations

Biophysical and Immunological Characterization and In Vivo Pharmacokinetics and Toxicology in Nonhuman Primates of the Anti-PD-1 Antibody Pembrolizumab

NMR Binding and Functional Assays for Detecting Inhibitors of S. aureus MnaA

Screening of Protein Kinases by ATP-STD NMR Spectroscopy

Discovery and Hit-to-Lead Optimization of Non-ATP Competitive MK2 (MAPKAPK2) Inhibitors

Non-Peptidic Small-Molecule Inhibitors of the Single-Chain Hepatitis C Virus NS3 Protease/NS4A Cofactor Complex Discovered by Structure-Based NMR Screening

Cover Feature: Diffusion Profiling of Therapeutic Proteins by Using Solution NMR Spectroscopy (ChemBioChem 7/2019)

Probing IgG1 F C –Multimodal Nanoparticle Interactions: A Combined Nuclear Magnetic Resonance and Molecular Dynamics Simulations Approach

Identification of preferred multimodal ligand‐binding regions on IgG1 F C using nuclear magnetic resonance and molecular dynamics simulations

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