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Adeno-Associated Virus (AAV) Vectors in the CNS

Current gene therapy, 2011-06, Vol.11 (3), p.181

McCown, Thomas J

2011

Volltextzugriff (PDF)

Optimizing promoters for recombinant adeno-associated virus-mediated gene expression in the peripheral and central nervous system using self-complementary vectors

Human gene therapy, 2011-09, Vol.22 (9), p.1143

2011

Volltextzugriff (PDF)

N -acetylaspartate supports the energetic demands of developmental myelination via oligodendroglial aspartoacylase

Neurobiology of disease, 2016-12, Vol.96, p.323-334

2016

Volltextzugriff (PDF)

Engineering and Selection of Shuffled AAV Genomes: A New Strategy for Producing Targeted Biological Nanoparticles

Molecular therapy, 2008-07, Vol.16 (7), p.1252-1260

2008

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Mutagenesis of Adeno-Associated Virus Type 2 Capsid Protein VP1 Uncovers New Roles for Basic Amino Acids in Trafficking and Cell-Specific Transduction

Journal of Virology, 2010-09, Vol.84 (17), p.8888-8902

2010

Volltextzugriff (PDF)

Current prospects and challenges for epilepsy gene therapy

Experimental neurology, 2013-06, Vol.244, p.27-35

2013

Volltextzugriff (PDF)

AAV Capsid-Promoter Interactions Determine CNS Cell-Selective Gene Expression In Vivo

Molecular therapy, 2020-05, Vol.28 (5), p.1373-1380

2020

Volltextzugriff (PDF)

Adeno-associated virus (AAV) gene therapy for neurological disease

Neuropharmacology, 2013-06, Vol.69, p.82-88

2013

Volltextzugriff (PDF)

Opposing actions of hippocampus TNFα receptors on limbic seizure susceptibility

Experimental neurology, 2013-09, Vol.247, p.429-437

2013

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Adeno-associated virus-mediated expression and constitutive secretion of galanin suppresses limbic seizure activity in vivo

Molecular therapy, 2006-07, Vol.14 (1), p.63-68

McCown, Thomas J

2006

Volltextzugriff (PDF)

Treatment Strategies Targeting Excess Hippocampal Activity Benefit Aged Rats with Cognitive Impairment

Neuropsychopharmacology (New York, N.Y.), 2010-03, Vol.35 (4), p.1016-1025

2010

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Generation of a Stable Cell Line Producing High-Titer Self-Inactivating Lentiviral Vectors

Molecular therapy, 2001-01, Vol.3 (1), p.97-104

2001

Volltextzugriff (PDF)

Viral Vector Reprogramming of Adult Resident Striatal Oligodendrocytes into Functional Neurons

Molecular therapy, 2017-04, Vol.25 (4), p.928-934

2017

Volltextzugriff (PDF)

Directed Evolution of a Novel Adeno-associated Virus (AAV) Vector That Crosses the Seizure-compromised Blood–Brain Barrier (BBB)

Molecular therapy, 2010-03, Vol.18 (3), p.570-578

2010

Volltextzugriff (PDF)

Neuropeptide Y signaling modulates the expression of ethanol-induced behavioral sensitization in mice

Addiction biology, 2012-03, Vol.17 (2), p.338-350

2012

Volltextzugriff (PDF)

Therapeutic Liabilities of in Vivo Viral Vector Tropism: Adeno-Associated Virus Vectors, NMDAR1 Antisense, and Focal Seizure Sensitivity

Molecular therapy, 2002-10, Vol.6 (4), p.495-500

2002

Volltextzugriff (PDF)

Adeno-associated virus (AAV) vectors in the CNS

Current gene therapy, 2005-06, Vol.5 (3), p.333

McCown, Thomas J

2005

Volltextzugriff (PDF)

Adeno-Associated Virus Vector-Mediated Expression and Constitutive Secretion of Galanin Suppresses Limbic Seizure Activity

Neurotherapeutics, 2009-04, Vol.6 (2), p.307-311

McCown, Thomas J.

2009

Volltextzugriff (PDF)

Overexpression of the steroidogenic enzyme cytochrome P450 side chain cleavage in the ventral tegmental area increases 3α,5α-THP and reduces long-term operant ethanol self-administration

The Journal of neuroscience, 2014-04, Vol.34 (17), p.5824-5834

2014

Volltextzugriff (PDF)

Overexpression of the Steroidogenic Enzyme Cytochrome P450 Side Chain Cleavage in the Ventral Tegmental Area Increases 3 alpha ,5 alpha -THP and Reduces Long-Term Operant Ethanol Self-Administration

The Journal of neuroscience, 2014-04, Vol.34 (17), p.5824-5834

2014

Volltextzugriff (PDF)

Attenuation of seizures and neuronal death by adeno-associated virus vector galanin expression and secretion

Nature medicine, 2003-08, Vol.9 (8), p.1076-1080

2003

Volltextzugriff (PDF)

Production of recombinant adeno-associated viral vectors and use in in vitro and in vivo administration

Current protocols in neuroscience, 2011-10, Vol.Chapter 4, p.Unit 4.17

2011

Volltextzugriff (PDF)

A trans-lentiviral packaging cell line for high-titer conditional self-inactivating HIV-1 vectors

Molecular therapy, 2006-08, Vol.14 (2), p.276-284

2006

Volltextzugriff (PDF)

Selective and rapid uptake of adeno-associated virus type 2 in brain

Human gene therapy, 1998-05, Vol.9 (8), p.1181-1186

1998

Volltextzugriff (PDF)

Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector

Brain research, 1996-03, Vol.713 (1), p.99-107

1996

Volltextzugriff (PDF)

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Adeno-Associated Virus (AAV) Vectors in the CNS

Optimizing promoters for recombinant adeno-associated virus-mediated gene expression in the peripheral and central nervous system using self-complementary vectors

N -acetylaspartate supports the energetic demands of developmental myelination via oligodendroglial aspartoacylase

Engineering and Selection of Shuffled AAV Genomes: A New Strategy for Producing Targeted Biological Nanoparticles

Mutagenesis of Adeno-Associated Virus Type 2 Capsid Protein VP1 Uncovers New Roles for Basic Amino Acids in Trafficking and Cell-Specific Transduction

Current prospects and challenges for epilepsy gene therapy

AAV Capsid-Promoter Interactions Determine CNS Cell-Selective Gene Expression In Vivo

Adeno-associated virus (AAV) gene therapy for neurological disease

Opposing actions of hippocampus TNFα receptors on limbic seizure susceptibility

Adeno-associated virus-mediated expression and constitutive secretion of galanin suppresses limbic seizure activity in vivo

Treatment Strategies Targeting Excess Hippocampal Activity Benefit Aged Rats with Cognitive Impairment

Generation of a Stable Cell Line Producing High-Titer Self-Inactivating Lentiviral Vectors

Viral Vector Reprogramming of Adult Resident Striatal Oligodendrocytes into Functional Neurons

Directed Evolution of a Novel Adeno-associated Virus (AAV) Vector That Crosses the Seizure-compromised Blood–Brain Barrier (BBB)

Neuropeptide Y signaling modulates the expression of ethanol-induced behavioral sensitization in mice

Therapeutic Liabilities of in Vivo Viral Vector Tropism: Adeno-Associated Virus Vectors, NMDAR1 Antisense, and Focal Seizure Sensitivity

Adeno-associated virus (AAV) vectors in the CNS

Adeno-Associated Virus Vector-Mediated Expression and Constitutive Secretion of Galanin Suppresses Limbic Seizure Activity

Overexpression of the steroidogenic enzyme cytochrome P450 side chain cleavage in the ventral tegmental area increases 3α,5α-THP and reduces long-term operant ethanol self-administration

Overexpression of the Steroidogenic Enzyme Cytochrome P450 Side Chain Cleavage in the Ventral Tegmental Area Increases 3 alpha ,5 alpha -THP and Reduces Long-Term Operant Ethanol Self-Administration

Attenuation of seizures and neuronal death by adeno-associated virus vector galanin expression and secretion

Production of recombinant adeno-associated viral vectors and use in in vitro and in vivo administration

A trans-lentiviral packaging cell line for high-titer conditional self-inactivating HIV-1 vectors

Selective and rapid uptake of adeno-associated virus type 2 in brain

Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector

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