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The emerging plasticity of SARS-CoV-2: The evolution of SARS-CoV-2 poses challenges for vaccines and immunotherapies.(VIEWPOINT: COVID-19)

Science (American Association for the Advancement of Science), 2021-03, Vol.371 (6536), p.1306

2021

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The emerging plasticity of SARS-CoV-2

Science (American Association for the Advancement of Science), 2021-03, Vol.371 (6536), p.1306-1308

2021

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Intractable Coronavirus Disease 2019 (COVID-19) and Prolonged Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Replication in a Chimeric Antigen Receptor-Modified T-Cell Therapy Recipient: A Case Study

Clinical infectious diseases, 2021-08, Vol.73 (3), p.e815-e821

2021

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Development of a Robust Cytopathic Effect-Based High-Throughput Screening Assay To Identify Novel Inhibitors of Dengue Virus

Antimicrobial Agents and Chemotherapy, 2012-06, Vol.56 (6), p.3399-3401

2012

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Innate immune signaling through differential RIPK1 expression promote tumor progression in head and neck squamous cell carcinoma

Carcinogenesis (New York), 2016-05, Vol.37 (5), p.522-529

2016

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Oligoadenylate synthetase 1 displays dual antiviral mechanisms in driving translational shutdown and protecting interferon production

Immunity (Cambridge, Mass.), 2024-03, Vol.57 (3), p.446-461.e7

2024

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Antibody Responses After mRNA-Based COVID-19 Vaccination in Residential Older Adults: Implications for Reopening

Journal of the American Medical Directors Association, 2021-08, Vol.22 (8), p.1593-1598

2021

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Human apolipoprotein E peptides inhibit hepatitis C virus entry by blocking virus binding

Hepatology (Baltimore, Md.), 2012-08, Vol.56 (2), p.484-491

2012

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Adaptation of advanced clinical virology assays from HIV-1 to SARS-CoV-2

Current opinion in HIV & AIDS, 2021-01, Vol.16 (1), p.3

2021

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Discordance between Etravirine Phenotype and Genotype-Based Predicted Phenotype for Subtype C HIV-1 from First-Line Antiretroviral Therapy Failures in South Africa

Antimicrobial agents and chemotherapy, 2020-04, Vol.64 (5)

2020

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Simian virus 40 large T antigen induces IFN-stimulated genes through ATR kinase

The Journal of immunology (1950), 2014-06, Vol.192 (12), p.5933-5942

2014

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Downregulation of IRF4 induces lytic reactivation of KSHV in primary effusion lymphoma cells

Virology (New York, N.Y.), 2014-06, Vol.458, p.4-10

2014

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Rapid Emergence of Potentially Transmissible Severe Acute Respiratory Syndrome Coronavirus 2 With Resistance to Combination Monoclonal Antibody Therapy

Open forum infectious diseases, 2023-05, Vol.10 (5), p.ofad278

2023

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Alpha-2c-Adrenergic Receptors Contribute to Basal Nasal Patency in the Anesthetized Cat

Pharmacology, 2010-01, Vol.85 (5), p.259-263

2010

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Bicyclic and tricyclic heterocycle derivatives as histamine H3 receptor antagonists for the treatment of obesity

Bioorganic & medicinal chemistry letters, 2013-11, Vol.23 (21), p.6004-6009

2013

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Discovery of MK-8318, a Potent and Selective CRTh2 Receptor Antagonist for the Treatment of Asthma

ACS medicinal chemistry letters, 2018-07, Vol.9 (7), p.679-684

2018

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Quality by design (QbD) of amide isosteres: 5,5-Disubstituted isoxazolines as potent CRTh2 antagonists with favorable pharmacokinetic and drug-like properties

Bioorganic & medicinal chemistry letters, 2014-03, Vol.24 (6), p.1615-1620

2014

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Synthesis and SAR studies of benzimidazolone derivatives as histamine H3-receptor antagonists

Bioorganic & medicinal chemistry letters, 2013-11, Vol.23 (21), p.6001-6003

2013

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Role of α2-adrenoceptors in electrical field stimulation-induced contraction of pig nasal mucosa and pharmacologic characterization of a novel α2C-adrenoceptor agonist

American journal of rhinology & allergy, 2013-03, Vol.27 (2), p.84

2013

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Reduction of hERG inhibitory activity in the 4-piperidinyl urea series of H3 antagonists

Bioorganic & medicinal chemistry letters, 2010-04, Vol.20 (7), p.2359-2364

2010

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Reduction of CYP450 inhibition in the 4-[(1H-imidazol-4-yl)methyl]piperidine series of histamine H3 receptor antagonists

Bioorganic & medicinal chemistry letters, 2006-02, Vol.16 (4), p.989-994

2006

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Novel histamine H3 receptor antagonists based on the 4-[(1H-imidazol-4-yl)methyl]piperidine scaffold

Bioorganic & medicinal chemistry letters, 2006-01, Vol.16 (2), p.395-399

2006

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SV40 Large T antigen induces ISGs through ATR Kinase

The Journal of immunology (1950), 2014-05, Vol.192 (12), p.5933-5942

2014

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The emerging plasticity of SARS-CoV-2: The evolution of SARS-CoV-2 poses challenges for vaccines and immunotherapies.(VIEWPOINT: COVID-19)

The emerging plasticity of SARS-CoV-2

Intractable Coronavirus Disease 2019 (COVID-19) and Prolonged Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Replication in a Chimeric Antigen Receptor-Modified T-Cell Therapy Recipient: A Case Study

Development of a Robust Cytopathic Effect-Based High-Throughput Screening Assay To Identify Novel Inhibitors of Dengue Virus

Innate immune signaling through differential RIPK1 expression promote tumor progression in head and neck squamous cell carcinoma

Oligoadenylate synthetase 1 displays dual antiviral mechanisms in driving translational shutdown and protecting interferon production

Therapy With Allogeneic Severe Acute Respiratory Syndrome Coronavirus-2–Specific T Cells for Persistent Coronavirus Disease 2019 in Immunocompromised Patients

Antibody Responses After mRNA-Based COVID-19 Vaccination in Residential Older Adults: Implications for Reopening

Human apolipoprotein E peptides inhibit hepatitis C virus entry by blocking virus binding

Adaptation of advanced clinical virology assays from HIV-1 to SARS-CoV-2

Discordance between Etravirine Phenotype and Genotype-Based Predicted Phenotype for Subtype C HIV-1 from First-Line Antiretroviral Therapy Failures in South Africa

Simian virus 40 large T antigen induces IFN-stimulated genes through ATR kinase

Downregulation of IRF4 induces lytic reactivation of KSHV in primary effusion lymphoma cells

Rapid Emergence of Potentially Transmissible Severe Acute Respiratory Syndrome Coronavirus 2 With Resistance to Combination Monoclonal Antibody Therapy

Alpha-2c-Adrenergic Receptors Contribute to Basal Nasal Patency in the Anesthetized Cat

Bicyclic and tricyclic heterocycle derivatives as histamine H3 receptor antagonists for the treatment of obesity

Discovery of MK-8318, a Potent and Selective CRTh2 Receptor Antagonist for the Treatment of Asthma

Potent and broad neutralization of SARS-CoV-2 variants of concern (VOCs) including omicron sub-lineages BA.1 and BA.2 by biparatopic human VH domains

Quality by design (QbD) of amide isosteres: 5,5-Disubstituted isoxazolines as potent CRTh2 antagonists with favorable pharmacokinetic and drug-like properties

Synthesis and SAR studies of benzimidazolone derivatives as histamine H3-receptor antagonists

Role of α2-adrenoceptors in electrical field stimulation-induced contraction of pig nasal mucosa and pharmacologic characterization of a novel α2C-adrenoceptor agonist

Reduction of hERG inhibitory activity in the 4-piperidinyl urea series of H3 antagonists

Reduction of CYP450 inhibition in the 4-[(1H-imidazol-4-yl)methyl]piperidine series of histamine H3 receptor antagonists

Novel histamine H3 receptor antagonists based on the 4-[(1H-imidazol-4-yl)methyl]piperidine scaffold

SV40 Large T antigen induces ISGs through ATR Kinase

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