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Alpha-synuclein suppression by targeted small interfering RNA in the primate substantia nigra

PloS one, 2010-08, Vol.5 (8), p.e12122

2010

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Lysosomal Degradation of α-Synuclein in Vivo

The Journal of biological chemistry, 2010-04, Vol.285 (18), p.13621-13629

2010

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Reduced Vesicular Storage of Dopamine Causes Progressive Nigrostriatal Neurodegeneration

The Journal of neuroscience, 2007-07, Vol.27 (30), p.8138-8148

2007

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Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration

Neurobiology of disease, 2007-02, Vol.25 (2), p.392-400

2007

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Paraquat Neurotoxicity Is Mediated by a Bak-dependent Mechanism

The Journal of biological chemistry, 2008-02, Vol.283 (6), p.3357-3364

2008

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Role of oxidative stress in paraquat‐induced dopaminergic cell degeneration

Journal of neurochemistry, 2005-05, Vol.93 (4), p.1030-1037

2005

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Environmental Risk Factors and Parkinson's Disease: Selective Degeneration of Nigral Dopaminergic Neurons Caused by the Herbicide Paraquat

Neurobiology of disease, 2002-07, Vol.10 (2), p.119-127

2002

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The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein

The Journal of biological chemistry, 2002-01, Vol.277 (3), p.1641-1644

2002

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Serine 129 Phosphorylation Reduces the Ability of α-Synuclein to Regulate Tyrosine Hydroxylase and Protein Phosphatase 2A in Vitro and in Vivo

The Journal of biological chemistry, 2010-06, Vol.285 (23), p.17648-17661

2010

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α-Synuclein expression in the substantia nigra of MPTP-lesioned non-human primates

Neurobiology of disease, 2005-12, Vol.20 (3), p.898-906

2005

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Nuclear Localization of α-Synuclein and Its Interaction with Histones

Biochemistry (Easton), 2003-07, Vol.42 (28), p.8465-8471

2003

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Enhanced alpha-synuclein expression in human neurodegenerative diseases: pathogenetic and therapeutic implications

Current protein & peptide science, 2009-10, Vol.10 (5), p.476-482

2009

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alpha -Synuclein Overexpression Protects against Paraquat-Induced Neurodegeneration

The Journal of neuroscience, 2003-04, Vol.23 (8), p.3095-3099

2003

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Effects of l‐dopa and other amino acids against paraquat‐induced nigrostriatal degeneration

Journal of neurochemistry, 2003-04, Vol.85 (1), p.82-86

2003

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Increased vulnerability of nigrostriatal terminals in DJ-1-deficient mice is mediated by the dopamine transporter

Neurobiology of disease, 2007-08, Vol.27 (2), p.141-150

2007

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Dieldrin exposure induces oxidative damage in the mouse nigrostriatal dopamine system

Experimental neurology, 2007-04, Vol.204 (2), p.619-630

2007

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Lack of nigrostriatal pathology in a rat model of proteasome inhibition

Annals of neurology, 2006-08, Vol.60 (2), p.256-260

2006

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Pathologic Modifications of α-Synuclein in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)-Treated Squirrel Monkeys

Journal of neuropathology and experimental neurology, 2008-08, Vol.67 (8), p.793-802

2008

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Age-related irreversible progressive nigrostriatal dopaminergic neurotoxicity in the paraquat and maneb model of the Parkinson's disease phenotype

The European journal of neuroscience, 2003-08, Vol.18 (3), p.589-600

2003

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Decreased α-synuclein expression in the aging mouse substantia nigra

Experimental neurology, 2009-12, Vol.220 (2), p.359-365

2009

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Aging of the nigrostriatal system in the squirrel monkey

Journal of comparative neurology (1911), 2004-04, Vol.471 (4), p.387-395

2004

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Reversibly Locking a Protein Fold in an Active Conformation with a Disulfide Bond: Integrin αL I Domains with High Affinity and Antagonist Activity in vivo

Proceedings of the National Academy of Sciences - PNAS, 2001-05, Vol.98 (11), p.6009-6014

2001

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Lack of Nigral Pathology in Transgenic Mice Expressing Human α-Synuclein Driven by the Tyrosine Hydroxylase Promoter

Neurobiology of disease, 2001-06, Vol.8 (3), p.535-539

2001

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Nicotine partially protects against paraquat-induced nigrostriatal damage in mice; link to α6β2 nAChRs

Journal of neurochemistry, 2007-01, Vol.100 (1), p.180-190

2007

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Restorative effects of platelet derived growth factor-BB in rodent models of Parkinson's disease

Journal of Parkinson's disease, 2011, Vol.1 (1), p.49-63

2011

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Alpha-synuclein suppression by targeted small interfering RNA in the primate substantia nigra

Lysosomal Degradation of α-Synuclein in Vivo

Reduced Vesicular Storage of Dopamine Causes Progressive Nigrostriatal Neurodegeneration

Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration

Paraquat Neurotoxicity Is Mediated by a Bak-dependent Mechanism

Role of oxidative stress in paraquat‐induced dopaminergic cell degeneration

Environmental Risk Factors and Parkinson's Disease: Selective Degeneration of Nigral Dopaminergic Neurons Caused by the Herbicide Paraquat

The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein

Serine 129 Phosphorylation Reduces the Ability of α-Synuclein to Regulate Tyrosine Hydroxylase and Protein Phosphatase 2A in Vitro and in Vivo

α-Synuclein expression in the substantia nigra of MPTP-lesioned non-human primates

Nuclear Localization of α-Synuclein and Its Interaction with Histones

Enhanced alpha-synuclein expression in human neurodegenerative diseases: pathogenetic and therapeutic implications

alpha -Synuclein Overexpression Protects against Paraquat-Induced Neurodegeneration

Effects of l‐dopa and other amino acids against paraquat‐induced nigrostriatal degeneration

Increased vulnerability of nigrostriatal terminals in DJ-1-deficient mice is mediated by the dopamine transporter

Dieldrin exposure induces oxidative damage in the mouse nigrostriatal dopamine system

Lack of nigrostriatal pathology in a rat model of proteasome inhibition

Pathologic Modifications of α-Synuclein in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)-Treated Squirrel Monkeys

Age-related irreversible progressive nigrostriatal dopaminergic neurotoxicity in the paraquat and maneb model of the Parkinson's disease phenotype

Decreased α-synuclein expression in the aging mouse substantia nigra

Aging of the nigrostriatal system in the squirrel monkey

Reversibly Locking a Protein Fold in an Active Conformation with a Disulfide Bond: Integrin αL I Domains with High Affinity and Antagonist Activity in vivo

Lack of Nigral Pathology in Transgenic Mice Expressing Human α-Synuclein Driven by the Tyrosine Hydroxylase Promoter

Nicotine partially protects against paraquat-induced nigrostriatal damage in mice; link to α6β2 nAChRs

Restorative effects of platelet derived growth factor-BB in rodent models of Parkinson's disease

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