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Hepatic stellate cells in physiology and pathology

The Journal of physiology, 2022-04, Vol.600 (8), p.1825-1837

2022

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Mitochondrial pyruvate transport: a historical perspective and future research directions

Biochemical journal, 2015-03, Vol.466 (3), p.443-454

2015

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Loss of Mitochondrial Pyruvate Carrier 2 in the Liver Leads to Defects in Gluconeogenesis and Compensation via Pyruvate-Alanine Cycling

Cell metabolism, 2015-10, Vol.22 (4), p.682-694

2015

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Mitochondrial Pyruvate Import Promotes Long-Term Survival of Antibody-Secreting Plasma Cells

Immunity (Cambridge, Mass.), 2016-07, Vol.45 (1), p.60-73

2016

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The role of VDAC in cell death: Friend or foe?

Biochimica et biophysica acta, 2012-06, Vol.1818 (6), p.1444-1450

2012

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The peptide hormone adropin regulates signal transduction pathways controlling hepatic glucose metabolism in a mouse model of diet-induced obesity

The Journal of biological chemistry, 2019-09, Vol.294 (36), p.13366-13377

2019

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Etomoxir: an old dog with new tricks

Journal of lipid research, 2024-09, Vol.65 (9), p.100604, Article 100604

2024

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Editorial: Diabetes and non-alcoholic fatty liver disease: points of physiological and mechanistic intersection and current co-therapeutic approaches

Frontiers in endocrinology (Lausanne), 2023-07, Vol.14, p.1253604-1253604

2023

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The Importance of Keeping Time in the Liver

Endocrinology (Philadelphia), 2021-02, Vol.162 (2), p.1

2021

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Obesity-related T cell dysfunction impairs immunosurveillance and increases cancer risk

Nature communications, 2024-04, Vol.15 (1), p.2835-2835, Article 2835

2024

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CrossTalk opposing view: Ketone bodies are not an important metabolic fuel for the heart

The Journal of physiology, 2022-03, Vol.600 (5), p.1005-1007

2022

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Rebuttal from Manoja K. Brahma, Adam R. Wende and Kyle S. McCommis

The Journal of physiology, 2022-03, Vol.600 (5), p.1011-1012

2022

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The Hepatic Mitochondrial Pyruvate Carrier as a Regulator of Systemic Metabolism and a Therapeutic Target for Treating Metabolic Disease

Biomolecules (Basel, Switzerland), 2023-01, Vol.13 (2), p.261

2023

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Targeting the mitochondrial pyruvate carrier attenuates fibrosis in a mouse model of nonalcoholic steatohepatitis

Hepatology (Baltimore, Md.), 2017-05, Vol.65 (5), p.1543-1556

2017

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Novel insulin sensitizer MSDC-0602K improves insulinemia and fatty liver disease in mice, alone and in combination with liraglutide

The Journal of biological chemistry, 2021-01, Vol.296, p.100807-100807, Article 100807

2021

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Mitochondrial Pyruvate Carrier 2 Hypomorphism in Mice Leads to Defects in Glucose-Stimulated Insulin Secretion

Cell reports (Cambridge), 2014-06, Vol.7 (6), p.2042-2053

2014

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PPAR α agonist fenofibrate attenuates iron-induced liver injury in mice by modulating the Sirt3 and β -catenin signaling

American journal of physiology: Gastrointestinal and liver physiology, 2021-09, Vol.321 (4), p.G262-G269

2021

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Double Cyclization Tandem Mass for Identification and Quantification of Phosphatidylcholines Using Isobaric Six-Plex Capillary nLC-MS/MS

Journal of the American Society for Mass Spectrometry, 2024-07, Vol.35 (7), p.1403-1412

2024

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Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice

The Journal of biological chemistry, 2022-02, Vol.298 (2), p.101554-101554, Article 101554

2022

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Loss of lipin 1‐mediated phosphatidic acid phosphohydrolase activity in muscle leads to skeletal myopathy in mice

The FASEB journal, 2019-01, Vol.33 (1), p.652-667

2019

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1786-P: The New Insulin Sensitizer MSDC-0602K Synergizes with the GLP-1 Receptor Agonist Liraglutide

Diabetes (New York, N.Y.), 2020-06, Vol.69 (Supplement_1)

2020

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NADPH and Glutathione Redox Link TCA Cycle Activity to Endoplasmic Reticulum Homeostasis

iScience, 2020-05, Vol.23 (5), p.101116, Article 101116

2020

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Treating Hepatic Steatosis and Fibrosis by Modulating Mitochondrial Pyruvate Metabolism

Cellular and molecular gastroenterology and hepatology, 2019-01, Vol.7 (2), p.275-284

2019

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213-LB: Mechanisms of Metabolic Cross Talk between Mitochondrial Pyruvate Carrier Inhibition and Branched-Chain Amino Acid Catabolism in Hepatocytes

Diabetes (New York, N.Y.), 2021-06, Vol.70 (Supplement_1)

2021

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Mitochondrial pyruvate carrier inhibition initiates metabolic crosstalk to stimulate branched chain amino acid catabolism

Molecular metabolism (Germany), 2023-04, Vol.70, p.101694, Article 101694

2023

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Hepatic stellate cells in physiology and pathology

Mitochondrial pyruvate transport: a historical perspective and future research directions

Loss of Mitochondrial Pyruvate Carrier 2 in the Liver Leads to Defects in Gluconeogenesis and Compensation via Pyruvate-Alanine Cycling

Mitochondrial Pyruvate Import Promotes Long-Term Survival of Antibody-Secreting Plasma Cells

The role of VDAC in cell death: Friend or foe?

The peptide hormone adropin regulates signal transduction pathways controlling hepatic glucose metabolism in a mouse model of diet-induced obesity

Etomoxir: an old dog with new tricks

Editorial: Diabetes and non-alcoholic fatty liver disease: points of physiological and mechanistic intersection and current co-therapeutic approaches

The Importance of Keeping Time in the Liver

Obesity-related T cell dysfunction impairs immunosurveillance and increases cancer risk

CrossTalk opposing view: Ketone bodies are not an important metabolic fuel for the heart

Rebuttal from Manoja K. Brahma, Adam R. Wende and Kyle S. McCommis

The Hepatic Mitochondrial Pyruvate Carrier as a Regulator of Systemic Metabolism and a Therapeutic Target for Treating Metabolic Disease

Targeting the mitochondrial pyruvate carrier attenuates fibrosis in a mouse model of nonalcoholic steatohepatitis

Novel insulin sensitizer MSDC-0602K improves insulinemia and fatty liver disease in mice, alone and in combination with liraglutide

Mitochondrial Pyruvate Carrier 2 Hypomorphism in Mice Leads to Defects in Glucose-Stimulated Insulin Secretion

PPAR α agonist fenofibrate attenuates iron-induced liver injury in mice by modulating the Sirt3 and β -catenin signaling

Double Cyclization Tandem Mass for Identification and Quantification of Phosphatidylcholines Using Isobaric Six-Plex Capillary nLC-MS/MS

Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice

Loss of lipin 1‐mediated phosphatidic acid phosphohydrolase activity in muscle leads to skeletal myopathy in mice

1786-P: The New Insulin Sensitizer MSDC-0602K Synergizes with the GLP-1 Receptor Agonist Liraglutide

NADPH and Glutathione Redox Link TCA Cycle Activity to Endoplasmic Reticulum Homeostasis

Treating Hepatic Steatosis and Fibrosis by Modulating Mitochondrial Pyruvate Metabolism

213-LB: Mechanisms of Metabolic Cross Talk between Mitochondrial Pyruvate Carrier Inhibition and Branched-Chain Amino Acid Catabolism in Hepatocytes

Mitochondrial pyruvate carrier inhibition initiates metabolic crosstalk to stimulate branched chain amino acid catabolism

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