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IBD candidate genes and intestinal barrier regulation

Inflammatory bowel diseases, 2014-10, Vol.20 (10), p.1829-1849

McCole, Declan F

2014

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ZOning in on Novel Roles for Zonula Occludens Proteins in Epithelial Repair

Gastroenterology (New York, N.Y. 1943), 2021-12, Vol.161 (6), p.1797-1800

Mccole, Declan F.

2021

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Finding a mate for MLCK: improving the potential for therapeutic targeting of gut permeability

Gut, 2022-07, Vol.72 (5), p.814-815

McCole, Declan F

2022

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Mechanisms of Intestinal Epithelial Barrier Dysfunction by Adherent-Invasive Escherichia coli

Cellular and molecular gastroenterology and hepatology, 2017-01, Vol.3 (1), p.41-50

2017

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T cell protein tyrosine phosphatase prevents STAT1 induction of claudin‐2 expression in intestinal epithelial cells

Annals of the New York Academy of Sciences, 2017-10, Vol.1405 (1), p.116-130

2017

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PTPN2 Regulates Interactions Between Macrophages and Intestinal Epithelial Cells to Promote Intestinal Barrier Function

Gastroenterology (New York, N.Y. 1943), 2020-11, Vol.159 (5), p.1763-1777.e14

2020

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The JAK-Inhibitor Tofacitinib Rescues Human Intestinal Epithelial Cells and Colonoids from Cytokine-Induced Barrier Dysfunction

Inflammatory bowel diseases, 2020-02, Vol.26 (3), p.407-422

2020

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Regulation of epithelial barrier function by the inflammatory bowel disease candidate gene, PTPN2

Annals of the New York Academy of Sciences, 2012-06, Vol.1257 (1), p.108-114

McCole, Declan F.

2012

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Deficiency of intestinal mucin‐2 ameliorates experimental alcoholic liver disease in mice

Hepatology (Baltimore, Md.), 2013-07, Vol.58 (1), p.108-119

2013

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JAK-STAT Pathway Regulation of Intestinal Permeability: Pathogenic Roles and Therapeutic Opportunities in Inflammatory Bowel Disease

Pharmaceuticals (Basel, Switzerland), 2021-08, Vol.14 (9), p.840

2021

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PTPN2 Regulates Inflammasome Activation and Controls Onset of Intestinal Inflammation and Colon Cancer

Cell reports (Cambridge), 2018-02, Vol.22 (7), p.1835-1848

2018

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Intranasal Exposure to Hog Dust Extract Promotes Endotoxemia and Increases Gene Expression of TNF‐α and Secretary Epithelial Cell Markers in Mouse Intestine

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Cholera Toxin Disrupts Barrier Function by Inhibiting Exocyst-Mediated Trafficking of Host Proteins to Intestinal Cell Junctions

Cell host & microbe, 2013-09, Vol.14 (3), p.294-305

2013

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Protein Tyrosine Phosphatase non‐Receptor Type 2 regulates IFN‐γ‐induced cytokine signaling in THP‐1 monocytes

Inflammatory bowel diseases, 2010-12, Vol.16 (12), p.2055-2064

2010

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Every breath you take: Impacts of environmental dust exposure on intestinal barrier function-from the gut-lung axis to COVID-19

American journal of physiology: Gastrointestinal and liver physiology, 2021-04, Vol.320 (4), p.G586-G600

2021

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Hydrogen peroxide scavenger, catalase, alleviates ion transport dysfunction in murine colitis

Clinical and experimental pharmacology & physiology, 2016-11, Vol.43 (11), p.1097-1106

2016

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Activation of protein tyrosine phosphatase non-receptor type 2 by spermidine exerts anti-inflammatory effects in human THP-1 monocytes and in a mouse model of acute colitis

PloS one, 2013-09, Vol.8 (9), p.e73703

2013

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AMP-activated Protein Kinase Mediates the Interferon-γ-induced Decrease in Intestinal Epithelial Barrier Function

The Journal of biological chemistry, 2009-10, Vol.284 (41), p.27952-27963

2009

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Autoimmune susceptibility gene PTPN2 is required for clearance of adherent-invasive Escherichia coli by integrating bacterial uptake and lysosomal defence

Gut, 2022-01, Vol.71 (1), p.89-99

2022

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Role of protein tyrosine phosphatases in regulating the immune system: implications for chronic intestinal inflammation

Inflammatory bowel diseases, 2015-03, Vol.21 (3), p.645-655

2015

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The JAK Inhibitor Tofacitinib Rescues Intestinal Barrier Defects Caused by Disrupted Epithelial-macrophage Interactions

Journal of Crohn's and colitis, 2021-03, Vol.15 (3), p.471-484

2021

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Protein tyrosine phosphatase non-receptor type 2 and inflammatory bowel disease

World journal of gastroenterology : WJG, 2016-01, Vol.22 (3), p.1034-1044

2016

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VSL#3 Probiotic Stimulates T-cell Protein Tyrosine Phosphatase-mediated Recovery of IFN-γ-induced Intestinal Epithelial Barrier Defects

Inflammatory bowel diseases, 2016-12, Vol.22 (12), p.2811-2823

2016

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Loss of PTPN2 Activity Alters Iron Handling Protein Expression in IBD Patients and Causes Iron Deficiency in Mice

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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A Simulated Microgravity Environment Causes a Sustained Defect in Epithelial Barrier Function

Scientific reports, 2019-11, Vol.9 (1), p.17531-15, Article 17531

2019

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IBD candidate genes and intestinal barrier regulation

ZOning in on Novel Roles for Zonula Occludens Proteins in Epithelial Repair

Finding a mate for MLCK: improving the potential for therapeutic targeting of gut permeability

Mechanisms of Intestinal Epithelial Barrier Dysfunction by Adherent-Invasive Escherichia coli

T cell protein tyrosine phosphatase prevents STAT1 induction of claudin‐2 expression in intestinal epithelial cells

PTPN2 Regulates Interactions Between Macrophages and Intestinal Epithelial Cells to Promote Intestinal Barrier Function

The JAK-Inhibitor Tofacitinib Rescues Human Intestinal Epithelial Cells and Colonoids from Cytokine-Induced Barrier Dysfunction

Regulation of epithelial barrier function by the inflammatory bowel disease candidate gene, PTPN2

Deficiency of intestinal mucin‐2 ameliorates experimental alcoholic liver disease in mice

JAK-STAT Pathway Regulation of Intestinal Permeability: Pathogenic Roles and Therapeutic Opportunities in Inflammatory Bowel Disease

PTPN2 Regulates Inflammasome Activation and Controls Onset of Intestinal Inflammation and Colon Cancer

Intranasal Exposure to Hog Dust Extract Promotes Endotoxemia and Increases Gene Expression of TNF‐α and Secretary Epithelial Cell Markers in Mouse Intestine

Cholera Toxin Disrupts Barrier Function by Inhibiting Exocyst-Mediated Trafficking of Host Proteins to Intestinal Cell Junctions

Protein Tyrosine Phosphatase non‐Receptor Type 2 regulates IFN‐γ‐induced cytokine signaling in THP‐1 monocytes

Every breath you take: Impacts of environmental dust exposure on intestinal barrier function-from the gut-lung axis to COVID-19

Hydrogen peroxide scavenger, catalase, alleviates ion transport dysfunction in murine colitis

Activation of protein tyrosine phosphatase non-receptor type 2 by spermidine exerts anti-inflammatory effects in human THP-1 monocytes and in a mouse model of acute colitis

AMP-activated Protein Kinase Mediates the Interferon-γ-induced Decrease in Intestinal Epithelial Barrier Function

Autoimmune susceptibility gene PTPN2 is required for clearance of adherent-invasive Escherichia coli by integrating bacterial uptake and lysosomal defence

Role of protein tyrosine phosphatases in regulating the immune system: implications for chronic intestinal inflammation

The JAK Inhibitor Tofacitinib Rescues Intestinal Barrier Defects Caused by Disrupted Epithelial-macrophage Interactions

Protein tyrosine phosphatase non-receptor type 2 and inflammatory bowel disease

VSL#3 Probiotic Stimulates T-cell Protein Tyrosine Phosphatase-mediated Recovery of IFN-γ-induced Intestinal Epithelial Barrier Defects

Loss of PTPN2 Activity Alters Iron Handling Protein Expression in IBD Patients and Causes Iron Deficiency in Mice

A Simulated Microgravity Environment Causes a Sustained Defect in Epithelial Barrier Function

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