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An overview of the clinical application of antisense oligonucleotides for RNA-targeting therapies

Current opinion in pharmacology, 2015-10, Vol.24, p.52-58

2015

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The Catholic church and bolshevism

B. Herder Book Co., 1931. 110 pp, 1931

McClorey, J A

1931

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Microwave properties of YBa2Cu3O7-x films at 35 GHz from magnetotransmission and magnetoreflection measurements

Physical review. B, Condensed matter, 1994-02, Vol.49 (6), p.4199-4208

1994

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How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse

Human molecular genetics, 2015-08, Vol.24 (15), p.4225-4237

2015

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Cell-Penetrating Peptide Conjugates of Steric Blocking Oligonucleotides as Therapeutics for Neuromuscular Diseases from a Historical Perspective to Current Prospects of Treatment

Nucleic acid therapeutics, 2019-02, Vol.29 (1), p.1-12

2019

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Multi-level omics analysis in a murine model of dystrophin loss and therapeutic restoration

Human molecular genetics, 2015-12, Vol.24 (23), p.6756-6768

2015

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Self-Assembly into Nanoparticles Is Essential for Receptor Mediated Uptake of Therapeutic Antisense Oligonucleotides

Nano letters, 2015-07, Vol.15 (7), p.4364-4373

2015

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Engineered extracellular vesicle decoy receptor-mediated modulation of the IL6 trans-signalling pathway in muscle

Biomaterials, 2021-01, Vol.266, p.120435-120435, Article 120435

2021

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An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides

Nature communications, 2022-07, Vol.13 (1), p.4036-4036, Article 4036

2022

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Expression Analysis in Multiple Muscle Groups and Serum Reveals Complexity in the MicroRNA Transcriptome of the mdx Mouse with Implications for Therapy

Molecular therapy. Nucleic acids, 2012, Vol.1 (8), p.e39-e39, Article e39

2012

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Serum proteomic profiling reveals fragments of MYOM3 as potential biomarkers for monitoring the outcome of therapeutic interventions in muscular dystrophies

Human molecular genetics, 2015-09, Vol.24 (17), p.4916-4932

2015

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Antisense pre-treatment increases gene therapy efficacy in dystrophic muscles

Human molecular genetics, 2016-08, Vol.25 (16), p.3555-3563

2016

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Identification of novel, therapy-responsive protein biomarkers in a mouse model of Duchenne muscular dystrophy by aptamer-based serum proteomics

Scientific reports, 2015-11, Vol.5 (1), p.17014-17014, Article 17014

2015

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Peptide-conjugated phosphodiamidate oligomer-mediated exon skipping has benefits for cardiac function in mdx and Cmah-/-mdx mouse models of Duchenne muscular dystrophy

PloS one, 2018-06, Vol.13 (6), p.e0198897-e0198897

2018

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Prevention of exercised induced cardiomyopathy following Pip-PMO treatment in dystrophic mdx mice

Scientific reports, 2015-03, Vol.5 (1), p.8986-8986, Article 8986

2015

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Immortalized Canine Dystrophic Myoblast Cell Lines for Development of Peptide-Conjugated Splice-Switching Oligonucleotides

Nucleic acid therapeutics, 2021-04, Vol.31 (2), p.172-181

2021

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Extracellular microRNAs are dynamic non-vesicular biomarkers of muscle turnover

Nucleic acids research, 2013-11, Vol.41 (20), p.9500

2013

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Uniform sarcolemmal dystrophin expression is required to prevent extracellular microRNA release and improve dystrophic pathology

Journal of cachexia, sarcopenia and muscle, 2020-04, Vol.11 (2), p.578-593

2020

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Fine Tuning of Phosphorothioate Inclusion in 2′-O-Methyl Oligonucleotides Contributes to Specific Cell Targeting for Splice-Switching Modulation

Frontiers in physiology, 2021-10, Vol.12, p.689179-689179

2021

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Cell-penetrating peptide-morpholino conjugates alter pre-mRNA splicing of DMD (Duchenne muscular dystrophy) and inhibit murine coronavirus replication in vivo

Biochemical Society transactions, 2007-08, Vol.35 (Pt 4), p.826-828

2007

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Control of backbone chemistry and chirality boost oligonucleotide splice switching activity

Nucleic acids research, 2022-06, Vol.50 (10), p.5443-5466

2022

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Splice-Switching Therapy for Spinal Muscular Atrophy

Genes, 2017-06, Vol.8 (6), p.161

2017

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P.193 Phosphoryl guanidine-containing backbone modifications enhance exon skipping, dystrophin restoration and survival in a severe mouse model for DMD

Neuromuscular disorders : NMD, 2022-10, Vol.32, p.S126

2022

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A ready to drink, plant-based oral nutritional supplement is highly complied with, palatable and tolerated in community-based patients at risk of disease-related malnutrition

Evaluation of the effects of a new ready to drink, plant-based oral nutritional supplement (ONS) in adult community patients at risk of disease-related malnutrition (DRM)

An overview of the clinical application of antisense oligonucleotides for RNA-targeting therapies

The Catholic church and bolshevism

Microwave properties of YBa2Cu3O7-x films at 35 GHz from magnetotransmission and magnetoreflection measurements

How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse

Cell-Penetrating Peptide Conjugates of Steric Blocking Oligonucleotides as Therapeutics for Neuromuscular Diseases from a Historical Perspective to Current Prospects of Treatment

Multi-level omics analysis in a murine model of dystrophin loss and therapeutic restoration

Self-Assembly into Nanoparticles Is Essential for Receptor Mediated Uptake of Therapeutic Antisense Oligonucleotides

Engineered extracellular vesicle decoy receptor-mediated modulation of the IL6 trans-signalling pathway in muscle

An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides

Expression Analysis in Multiple Muscle Groups and Serum Reveals Complexity in the MicroRNA Transcriptome of the mdx Mouse with Implications for Therapy

Serum proteomic profiling reveals fragments of MYOM3 as potential biomarkers for monitoring the outcome of therapeutic interventions in muscular dystrophies

Antisense pre-treatment increases gene therapy efficacy in dystrophic muscles

Identification of novel, therapy-responsive protein biomarkers in a mouse model of Duchenne muscular dystrophy by aptamer-based serum proteomics

Peptide-conjugated phosphodiamidate oligomer-mediated exon skipping has benefits for cardiac function in mdx and Cmah-/-mdx mouse models of Duchenne muscular dystrophy

Prevention of exercised induced cardiomyopathy following Pip-PMO treatment in dystrophic mdx mice

Immortalized Canine Dystrophic Myoblast Cell Lines for Development of Peptide-Conjugated Splice-Switching Oligonucleotides

Extracellular microRNAs are dynamic non-vesicular biomarkers of muscle turnover

Uniform sarcolemmal dystrophin expression is required to prevent extracellular microRNA release and improve dystrophic pathology

Fine Tuning of Phosphorothioate Inclusion in 2′-O-Methyl Oligonucleotides Contributes to Specific Cell Targeting for Splice-Switching Modulation

Cell-penetrating peptide-morpholino conjugates alter pre-mRNA splicing of DMD (Duchenne muscular dystrophy) and inhibit murine coronavirus replication in vivo

Control of backbone chemistry and chirality boost oligonucleotide splice switching activity

Splice-Switching Therapy for Spinal Muscular Atrophy

P.193 Phosphoryl guanidine-containing backbone modifications enhance exon skipping, dystrophin restoration and survival in a severe mouse model for DMD

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