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Taurine rescues pancreatic β‐cell stress by stimulating α‐cell transdifferentiation

BioFactors (Oxford), 2023-05, Vol.49 (3), p.646-662

2023

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Development and Functional Characterization of Insulin-releasing Human Pancreatic Beta Cell Lines Produced by Electrofusion

The Journal of biological chemistry, 2011-06, Vol.286 (25), p.21982-21992

2011

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Cystic Fibrosis–Related Diabetes: Pathophysiology and Therapeutic Challenges

Clinical Medicine Insights: Endocrinology and Diabetes, 2019, Vol.12, p.1179551419851770-1179551419851770

2019

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l-Arginine is essential for pancreatic β-cell functional integrity, metabolism and defense from inflammatory challenge

Journal of endocrinology, 2011-10, Vol.211 (1), p.87-97

2011

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Configuration of electrofusion-derived human insulin-secreting cell line as pseudoislets enhances functionality and therapeutic utility

Journal of endocrinology, 2012-09, Vol.214 (3), p.257-265

2012

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Role of islet structure and cellular interactions in the control of insulin secretion

Islets, 2011-03, Vol.3 (2), p.41-47

2011

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Pro-inflammatory cytokines increase glucose, alanine and triacylglycerol utilization but inhibit insulin secretion in a clonal pancreatic β-cell line

Journal of endocrinology, 2007-10, Vol.195 (1), p.113-123

2007

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Comparison of insulin release from MIN6 pseudoislets and pancreatic islets of Langerhans reveals importance of homotypic cell interactions

Pancreas, 2010-10, Vol.39 (7), p.1016-1023

2010

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Molecular determinants and intracellular targets of taurine signalling in pancreatic islet β‐cells

Acta Physiologica, 2024-03, Vol.240 (3), p.e14101-n/a

2024

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NKCC transport mediates the insulinotropic effects of taurine and other small neutral amino acids

Life sciences (1973), 2023-03, Vol.316, p.121402-121402, Article 121402

2023

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Overexpression of the malate-aspartate NADH shuttle member Aralar1 in the clonal beta-cell line BRIN-BD11 enhances amino-acid-stimulated insulin secretion and cell metabolism

Clinical science (1979), 2009-09, Vol.117 (9), p.321-330

2009

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Toll-like receptor agonist induced changes in clonal rat BRIN-BD11 β-cell insulin secretion and signal transduction

Journal of endocrinology, 2009-09, Vol.202 (3), p.365-373

2009

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Mechanisms of toxicity by proinflammatory cytokines in a novel human pancreatic beta cell line, 1.1B4

Biochimica et biophysica acta, 2014-01, Vol.1840 (1), p.136-145

2014

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Implanting 1.1B4 human β-cell pseudoislets improves glycaemic control in diabetic severe combined immune deficient mice

World journal of diabetes, 2016-11, Vol.7 (19), p.523-533

2016

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Differential molecular and cellular responses of GLP-1 secreting L-cells and pancreatic alpha cells to glucotoxicity and lipotoxicity

Experimental cell research, 2015-08, Vol.336 (1), p.100-108

2015

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Glutamine regulates expression of key transcription factor, signal transduction, metabolic gene, and protein expression in a clonal pancreatic β-cell line

Journal of endocrinology, 2006-09, Vol.190 (3), p.719-727

2006

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Molecular Mechanisms of Toxicity and Cell Damage by Chemicals in a Human Pancreatic Beta Cell Line, 1.1B4

Pancreas, 2016-10, Vol.45 (9), p.1320-1329

2016

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L-Alanine induces changes in metabolic and signal transduction gene expression in a clonal rat pancreatic beta-cell line and protects from pro-inflammatory cytokine-induced apoptosis

Clinical science (1979), 2005-11, Vol.109 (5), p.447-455

2005

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Islet-intrinsic effects of CFTR mutation

Diabetologia, 2016-07, Vol.59 (7), p.1350-1355

2016

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Pseudoislet formation enhances gene expression, insulin secretion and cytoprotective mechanisms of clonal human insulin-secreting 1.1B4 cells

Pflügers Archiv, 2015-10, Vol.467 (10), p.2219-2228

2015

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Physiological regulation of the pancreatic β‐cell: functional insights for understanding and therapy of diabetes

Experimental physiology, 2007-05, Vol.92 (3), p.481-496

McClenaghan, Neville H.

2007

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Actions of glucagon-like peptide-1 on KATP channel-dependent and -independent effects of glucose, sulphonylureas and nateglinide

Journal of endocrinology, 2006-09, Vol.190 (3), p.889-896

2006

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Effects of lipotoxicity on a novel insulin-secreting human pancreatic β-cell line, 1.1B4

Biological chemistry, 2013-07, Vol.394 (7), p.909-918

2013

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Prolonged L -alanine exposure induces changes in metabolism, Ca2+ handling and desensitization of insulin secretion in clonal pancreatic β-cells

Clinical science (1979), 2009-02, Vol.116 (4), p.341-351

2009

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Stem Cell-Based Approaches for the Treatment of Diabetes

Stem cells international, 2011-01, Vol.2011 (2011), p.1-8

2011

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Taurine rescues pancreatic β‐cell stress by stimulating α‐cell transdifferentiation

Development and Functional Characterization of Insulin-releasing Human Pancreatic Beta Cell Lines Produced by Electrofusion

Cystic Fibrosis–Related Diabetes: Pathophysiology and Therapeutic Challenges

l-Arginine is essential for pancreatic β-cell functional integrity, metabolism and defense from inflammatory challenge

Configuration of electrofusion-derived human insulin-secreting cell line as pseudoislets enhances functionality and therapeutic utility

Role of islet structure and cellular interactions in the control of insulin secretion

Pro-inflammatory cytokines increase glucose, alanine and triacylglycerol utilization but inhibit insulin secretion in a clonal pancreatic β-cell line

Comparison of insulin release from MIN6 pseudoislets and pancreatic islets of Langerhans reveals importance of homotypic cell interactions

Molecular determinants and intracellular targets of taurine signalling in pancreatic islet β‐cells

NKCC transport mediates the insulinotropic effects of taurine and other small neutral amino acids

Overexpression of the malate-aspartate NADH shuttle member Aralar1 in the clonal beta-cell line BRIN-BD11 enhances amino-acid-stimulated insulin secretion and cell metabolism

Toll-like receptor agonist induced changes in clonal rat BRIN-BD11 β-cell insulin secretion and signal transduction

Mechanisms of toxicity by proinflammatory cytokines in a novel human pancreatic beta cell line, 1.1B4

Implanting 1.1B4 human β-cell pseudoislets improves glycaemic control in diabetic severe combined immune deficient mice

Differential molecular and cellular responses of GLP-1 secreting L-cells and pancreatic alpha cells to glucotoxicity and lipotoxicity

Glutamine regulates expression of key transcription factor, signal transduction, metabolic gene, and protein expression in a clonal pancreatic β-cell line

Molecular Mechanisms of Toxicity and Cell Damage by Chemicals in a Human Pancreatic Beta Cell Line, 1.1B4

L-Alanine induces changes in metabolic and signal transduction gene expression in a clonal rat pancreatic beta-cell line and protects from pro-inflammatory cytokine-induced apoptosis

Islet-intrinsic effects of CFTR mutation

Pseudoislet formation enhances gene expression, insulin secretion and cytoprotective mechanisms of clonal human insulin-secreting 1.1B4 cells

Physiological regulation of the pancreatic β‐cell: functional insights for understanding and therapy of diabetes

Actions of glucagon-like peptide-1 on KATP channel-dependent and -independent effects of glucose, sulphonylureas and nateglinide

Effects of lipotoxicity on a novel insulin-secreting human pancreatic β-cell line, 1.1B4

Prolonged L -alanine exposure induces changes in metabolism, Ca2+ handling and desensitization of insulin secretion in clonal pancreatic β-cells

Stem Cell-Based Approaches for the Treatment of Diabetes

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