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Slow and steady wins the race: Optimizing lentiviral vector production for efficient clinical-scale manufacturing

Molecular therapy. Methods & clinical development, 2023-09, Vol.30, p.484-485

McCarron, Alexandra

2023

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Challenges of up-scaling lentivirus production and processing

Journal of biotechnology, 2016-12, Vol.240, p.23-30

2016

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Airway disease phenotypes in animal models of cystic fibrosis

Respiratory research, 2018-04, Vol.19 (1), p.54-54, Article 54

2018

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To bead or not to bead: A review of Pseudomonas aeruginosa lung infection models for cystic fibrosis

Frontiers in physiology, 2023-02, Vol.14, p.1104856-1104856

2023

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Effect of elexacaftor-tezacaftor-ivacaftor on nasal potential difference and lung function in Phe508del rats

Frontiers in pharmacology, 2024-03, Vol.15, p.1362325

2024

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Single-Dose Lentiviral Mediated Gene Therapy Recovers CFTR Function in Cystic Fibrosis Knockout Rats

Frontiers in pharmacology, 2021-05, Vol.12, p.682299-682299

2021

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Essential Fatty Acid Deficiency in Cystic Fibrosis Disease Progression: Role of Genotype and Sex

Nutrients, 2022-11, Vol.14 (21), p.4666

2022

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Corrigendum: Effect of elexacaftor-tezacaftor-ivacaftor on nasal potential difference and lung function in Phe508del rats

Frontiers in pharmacology, 2024-05, Vol.15, p.1428213

2024

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Improved in-vivo airway gene transfer via magnetic-guidance, with protocol development informed by synchrotron imaging

Scientific reports, 2022-05, Vol.12 (1), p.9000-9000, Article 9000

2022

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Breaching the Delivery Barrier: Chemical and Physical Airway Epithelium Disruption Strategies for Enhancing Lentiviral-Mediated Gene Therapy

Frontiers in pharmacology, 2021-04, Vol.12, p.669635-669635

2021

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Methods for dynamic synchrotron X‐ray respiratory imaging in live animals

Journal of synchrotron radiation, 2020-01, Vol.27 (1), p.164-175

2020

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Changes in Essential Fatty Acids and Ileal Genes Associated with Metabolizing Enzymes and Fatty Acid Transporters in Rodent Models of Cystic Fibrosis

International journal of molecular sciences, 2023-04, Vol.24 (8), p.7194

2023

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Animal and Cell Culture Models for Cystic Fibrosis: Which Model Is Right for Your Application?

The American journal of pathology, 2021-02, Vol.191 (2), p.228-242

2021

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Effective viral-mediated lung gene therapy: is airway surface preparation necessary?

Gene therapy, 2023-06, Vol.30 (6), p.469-477

2023

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Animal and Cell Culture Models for Cystic Fibrosis

The American journal of pathology, 2021-02, Vol.191 (2), p.228-242

2021

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Ultra-fast in vivo directional dark-field x-ray imaging for visualising magnetic control of particles for airway gene delivery

Physics in medicine & biology, 2024-05, Vol.69 (10), p.105025

2024

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Repeat or single-dose lentiviral vector administration to mouse lungs? It's all about the timing

Gene therapy, 2023-09, Vol.30 (9), p.698-705

2023

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Particle coating alters mucociliary transit in excised rat trachea: A synchrotron X-ray imaging study

Scientific reports, 2019-07, Vol.9 (1), p.10983-10, Article 10983

2019

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Comparison of Physical Perturbation Devices for Enhancing Lentiviral Vector-Mediated Gene Transfer to the Airway Epithelium

Human gene therapy, 2022-10, Vol.33 (19-20), p.1062

2022

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Lentiviral vector gene therapy and CFTR modulators show comparable effectiveness in cystic fibrosis rat airway models

Gene therapy, 2024-08

2024

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The Effects of Conditioning and Lentiviral Vector Pseudotype on Short- and Long-Term Airway Reporter Gene Expression in Mice

Human gene therapy, 2021-08, Vol.32 (15-16), p.817

2021

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Transient Lentiviral Vector Production Using a Packed-Bed Bioreactor System

Human gene therapy. Part B. Methods, 2019-06, Vol.30 (3), p.93

2019

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Towards automated in vivo tracheal mucociliary transport measurement: Detecting and tracking particle movement in synchrotron phase-contrast x-ray images

Physics in medicine & biology, 2020-07, Vol.65 (14), p.145012-145012

2020

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Phenotypic Characterization and Comparison of Cystic Fibrosis Rat Models Generated Using CRISPR/Cas9 Gene Editing

The American journal of pathology, 2020-05, Vol.190 (5), p.977-993

2020

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Ultra-fastin vivodirectional dark-field x-ray imaging for visualising magnetic control of particles for airway gene delivery

Physics in medicine & biology, 2024-05, Vol.69 (10)

2024

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Slow and steady wins the race: Optimizing lentiviral vector production for efficient clinical-scale manufacturing

Challenges of up-scaling lentivirus production and processing

Airway disease phenotypes in animal models of cystic fibrosis

To bead or not to bead: A review of Pseudomonas aeruginosa lung infection models for cystic fibrosis

Effect of elexacaftor-tezacaftor-ivacaftor on nasal potential difference and lung function in Phe508del rats

Single-Dose Lentiviral Mediated Gene Therapy Recovers CFTR Function in Cystic Fibrosis Knockout Rats

Essential Fatty Acid Deficiency in Cystic Fibrosis Disease Progression: Role of Genotype and Sex

Corrigendum: Effect of elexacaftor-tezacaftor-ivacaftor on nasal potential difference and lung function in Phe508del rats

Improved in-vivo airway gene transfer via magnetic-guidance, with protocol development informed by synchrotron imaging

Breaching the Delivery Barrier: Chemical and Physical Airway Epithelium Disruption Strategies for Enhancing Lentiviral-Mediated Gene Therapy

Methods for dynamic synchrotron X‐ray respiratory imaging in live animals

Changes in Essential Fatty Acids and Ileal Genes Associated with Metabolizing Enzymes and Fatty Acid Transporters in Rodent Models of Cystic Fibrosis

Animal and Cell Culture Models for Cystic Fibrosis: Which Model Is Right for Your Application?

Effective viral-mediated lung gene therapy: is airway surface preparation necessary?

Animal and Cell Culture Models for Cystic Fibrosis

Ultra-fast in vivo directional dark-field x-ray imaging for visualising magnetic control of particles for airway gene delivery

Repeat or single-dose lentiviral vector administration to mouse lungs? It's all about the timing

Particle coating alters mucociliary transit in excised rat trachea: A synchrotron X-ray imaging study

Comparison of Physical Perturbation Devices for Enhancing Lentiviral Vector-Mediated Gene Transfer to the Airway Epithelium

Lentiviral vector gene therapy and CFTR modulators show comparable effectiveness in cystic fibrosis rat airway models

The Effects of Conditioning and Lentiviral Vector Pseudotype on Short- and Long-Term Airway Reporter Gene Expression in Mice

Transient Lentiviral Vector Production Using a Packed-Bed Bioreactor System

Towards automated in vivo tracheal mucociliary transport measurement: Detecting and tracking particle movement in synchrotron phase-contrast x-ray images

Phenotypic Characterization and Comparison of Cystic Fibrosis Rat Models Generated Using CRISPR/Cas9 Gene Editing

Ultra-fastin vivodirectional dark-field x-ray imaging for visualising magnetic control of particles for airway gene delivery

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