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TMPRSS6 as a Therapeutic Target for Disorders of Erythropoiesis and Iron Homeostasis

Advances in therapy, 2023-04, Vol.40 (4), p.1317-1333

2023

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Peripheral reduction of FGFR4 with antisense oligonucleotides increases metabolic rate and lowers adiposity in diet-induced obese mice

PloS one, 2013-07, Vol.8 (7), p.e66923

2013

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IL-4 Receptor Alpha Signaling through Macrophages Differentially Regulates Liver Fibrosis Progression and Reversal

EBioMedicine, 2018-03, Vol.29, p.92-103

2018

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Allele-Specific Inhibition of Rhodopsin With an Antisense Oligonucleotide Slows Photoreceptor Cell Degeneration

Investigative ophthalmology & visual science, 2015-10, Vol.56 (11), p.6362-6375

2015

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New Potent Antihyperglycemic Agents in db/db Mice: Synthesis and Structure−Activity Relationship Studies of (4-Substituted benzyl)(trifluoromethyl)pyrazoles and -pyrazolones

Journal of medicinal chemistry, 1996-09, Vol.39 (20), p.3920-3928

1996

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In vivo reduction of hepatitis B virus antigenemia and viremia by antisense oligonucleotides

Journal of hepatology, 2016-04, Vol.64 (4), p.781-789

2016

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Antisense oligonucleotide treatment ameliorates alpha-1 antitrypsin-related liver disease in mice

The Journal of clinical investigation, 2014-01, Vol.124 (1), p.251-261

2014

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Reduction in ocular complement factor B protein in mice and monkeys by systemic administration of factor B antisense oligonucleotide

Molecular vision, 2017-08, Vol.23, p.561-571

2017

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Inhibition of the alternative complement pathway by antisense oligonucleotides targeting complement factor B improves lupus nephritis in mice

Immunobiology (1979), 2016-06, Vol.221 (6), p.701-708

2016

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593 Antisense Oligonucleotide Reduction of Mutant Alpha-1 Antitrypsin Protein for the Treatment of Alpha-1 Antitrypsin Liver Disease

Gastroenterology (New York, N.Y. 1943), 2012-05, Vol.142 (5), p.S-919-S-919

2012

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Identification of a Novel Hypothalamic Neuropeptide Y Receptor Associated with Feeding Behavior

The Journal of biological chemistry, 1996-10, Vol.271 (42), p.26315-26319

1996

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Molecular Characterization of a Second Mouse Pancreatic Polypeptide Receptor and Its Inactivated Human Homologue

The Journal of biological chemistry, 1996-11, Vol.271 (44), p.27776-27781

1996

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Clinical Trial Design for Alpha-1 Antitrypsin Deficiency: A Model for Rare Diseases

Chronic obstructive pulmonary diseases, 2015-04, Vol.2 (2), p.177-190

2015

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Studies on New Acidic Azoles as Glucose-Lowering Agents in Obese, Diabetic db/db Mice

Journal of medicinal chemistry, 1995-02, Vol.38 (4), p.617-628

1995

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Cloning and characterization of a novel receptor to pancreatic polypeptide, a member of the neuropeptide Y receptor family

FEBS letters, 1996-02, Vol.381 (1), p.58-62

1996

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Antihyperglycemic activity of novel substituted 3H-1,2,3,5-oxathiadiazole 2-oxides

Journal of medicinal chemistry, 1992-04, Vol.35 (7), p.1176-1183

1992

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Synthesis and antihyperglycemic activity of novel 5-(naphthalenylsulfonyl)-2,4-thiazolidinediones

Journal of medicinal chemistry, 1990-05, Vol.33 (5), p.1418-1423

1990

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Metabolic abnormalities of the hyperglycemic obese Zucker rat

Metabolism, clinical and experimental, 1992-05, Vol.41 (5), p.522-525

1992

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Degenerated intramural pericytes ('ghost cells') in the retinal capillaries of diabetic rats

Current eye research, 1991-01, Vol.10 (4), p.339-350

1991

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Perfluorocarbon-based antidiabetic agents

Journal of medicinal chemistry, 1992-03, Vol.35 (5), p.944-953

1992

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Peripheral Reduction of FGFR4 with Antisense Oligonucleotides Increases Metabolic Rate and Lowers Adiposity in Diet-Induced Obese Mice. e66923

PloS one, 2013-07, Vol.8 (7)

2013

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Using antisense technology to develop a novel therapy for α-1 antitrypsin deficient (AATD) liver disease and to model AATD lung disease

Rare diseases (Austin, Tex.), 2014, Vol.2 (1), p.e28511-e28511

2014

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Antihyperglycemic activity of novel naphthalenyl 3H-1,2,3,5-oxathiadiazole 2-oxides

Journal of medicinal chemistry, 1993-08, Vol.36 (17), p.2485-2493

1993

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Induction of insulin resistance in normal adipose tissue by uremic human serum

Kidney international, 1984-02, Vol.25 (2), p.416-421

1984

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Degenerated intramural pericytes ('ghost cells') in the retinal capillaries of diabetic rats: Erratum

Current eye research, 1991, Vol.10 (9), p.893-893

1991

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TMPRSS6 as a Therapeutic Target for Disorders of Erythropoiesis and Iron Homeostasis

Peripheral reduction of FGFR4 with antisense oligonucleotides increases metabolic rate and lowers adiposity in diet-induced obese mice

IL-4 Receptor Alpha Signaling through Macrophages Differentially Regulates Liver Fibrosis Progression and Reversal

Allele-Specific Inhibition of Rhodopsin With an Antisense Oligonucleotide Slows Photoreceptor Cell Degeneration

New Potent Antihyperglycemic Agents in db/db Mice: Synthesis and Structure−Activity Relationship Studies of (4-Substituted benzyl)(trifluoromethyl)pyrazoles and -pyrazolones

In vivo reduction of hepatitis B virus antigenemia and viremia by antisense oligonucleotides

Antisense oligonucleotide treatment ameliorates alpha-1 antitrypsin-related liver disease in mice

Reduction in ocular complement factor B protein in mice and monkeys by systemic administration of factor B antisense oligonucleotide

Inhibition of the alternative complement pathway by antisense oligonucleotides targeting complement factor B improves lupus nephritis in mice

593 Antisense Oligonucleotide Reduction of Mutant Alpha-1 Antitrypsin Protein for the Treatment of Alpha-1 Antitrypsin Liver Disease

Identification of a Novel Hypothalamic Neuropeptide Y Receptor Associated with Feeding Behavior

Molecular Characterization of a Second Mouse Pancreatic Polypeptide Receptor and Its Inactivated Human Homologue

Clinical Trial Design for Alpha-1 Antitrypsin Deficiency: A Model for Rare Diseases

Studies on New Acidic Azoles as Glucose-Lowering Agents in Obese, Diabetic db/db Mice

Cloning and characterization of a novel receptor to pancreatic polypeptide, a member of the neuropeptide Y receptor family

Antihyperglycemic activity of novel substituted 3H-1,2,3,5-oxathiadiazole 2-oxides

Synthesis and antihyperglycemic activity of novel 5-(naphthalenylsulfonyl)-2,4-thiazolidinediones

Metabolic abnormalities of the hyperglycemic obese Zucker rat

Degenerated intramural pericytes ('ghost cells') in the retinal capillaries of diabetic rats

Perfluorocarbon-based antidiabetic agents

Peripheral Reduction of FGFR4 with Antisense Oligonucleotides Increases Metabolic Rate and Lowers Adiposity in Diet-Induced Obese Mice. e66923

Using antisense technology to develop a novel therapy for α-1 antitrypsin deficient (AATD) liver disease and to model AATD lung disease

Antihyperglycemic activity of novel naphthalenyl 3H-1,2,3,5-oxathiadiazole 2-oxides

Induction of insulin resistance in normal adipose tissue by uremic human serum

Degenerated intramural pericytes ('ghost cells') in the retinal capillaries of diabetic rats: Erratum

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