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Synthesis and antifolate activity of 5-methyl-5,10-dideaza analogs of aminopterin and folic acid and an alternative synthesis of 5,10-dideazatetrahydrofolic acid, a potent inhibitor of glycinamide ribonucleotide formyltransferase

Journal of medicinal chemistry, 1988-11, Vol.31 (11), p.2164-2169

1988

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Syntheses and evaluation as antifolates of MTX analogs derived from 2,.omega.-diaminoalkanoic acids

Journal of medicinal chemistry, 1985-08, Vol.28 (8), p.1016-1025

1985

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Syntheses and antifolate activity of 5-methyl-5-deaza analogs of aminopterin, methotrexate, folic acid, and N10-methylfolic acid

Journal of medicinal chemistry, 1986-06, Vol.29 (6), p.1080-1087

1986

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10-Propargylaminopterin and alkyl homologs of methotrexate as inhibitors of folate metabolism

Journal of medicinal chemistry, 1982-07, Vol.25 (7), p.877-880

1982

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10-Propargylaminopterin and alkyl homologues of methotrexate as inhibitors of folate metabolism

Journal of medicinal chemistry, 1982-07, Vol.25 (7), p.877-880

1982

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Synthesis of chlorozotocin, the 2-chloroethyl analog of the anticancer antibiotic streptozotocin

Journal of medicinal chemistry, 1975-01, Vol.18 (1), p.104-106

1975

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Carcinogenic Nitrosamines: Hundred-Gram Preparations of N-Nitrosodiethanolamine and α-Ureidodimethylnitrosamine

Synthesis (Stuttgart), 1984, Vol.1984 (4), p.311-313

1984

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Synthesis of 10-propargylfolic acid from 2-amino-6-(bromomethyl)-4(1h)-pteridinone

Journal of heterocyclic chemistry, 1987-01, Vol.24 (1), p.279-282

1987

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The Modes of Decomposition of 1,3-Bis(2-chloroethyl)-1-nitrosourea and Related Compounds

Journal of medicinal chemistry, 1967-07, Vol.10 (4), p.668-674

1967

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Decomposition of N-(2-chloroethyl)-N-nitrosoureas in aqueous media

Journal of medicinal chemistry, 1975-06, Vol.18 (6), p.568-571

1975

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cis-4-[[[(2-Chloroethyl)nitrosoamino]carbonyl]methylamino]cyclohexanecarboxylic acid, a nitrosourea with latent activity against an experimental solid tumor

Journal of medicinal chemistry, 1984-01, Vol.27 (1), p.97-99

1984

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Comparison of the properties of metabolites of CCNU

Biochemical pharmacology, 1977-12, Vol.26 (24), p.2331-2336

1977

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5-Substituted-5-Deaza Analogues of Classical Antifolates

Montreal, Canada, June 15–20, 1986, 2019, Vol.8, p.1001-1004

2019

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Synthesis and biologic evaluation of major metabolites of N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea

Journal of medicinal chemistry, 1975-06, Vol.18 (6), p.634-637

1975

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Inhibition of solid tumors by nitrosoureas. 1. Lewis lung carcinoma

Journal of medicinal chemistry, 1977-02, Vol.20 (2), p.291-295

1977

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Synthesis of analogs of N-(2-chloroethyl)-N'-(trans-4-methylcyclohexyl)-N-nitrosourea for evaluation as anticancer agents

Journal of medicinal chemistry, 1977-02, Vol.20 (2), p.279-290

1977

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L-Chlorozotocin

Journal of medicinal chemistry, 1979-05, Vol.22 (5), p.597-599

1979

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A synthetic approach to poly(gamma-glutamyl) congugates of methotrexate

Journal of medicinal chemistry, 1983-02, Vol.26 (2), p.291-294

1983

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Syntheses and evaluation as antifolates of MTX analogues derived from 2,w-diaminoalkanoic acids

Journal of medicinal chemistry, 1985, Vol.28 (8), p.1016-1025

1985

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cis-4-[[[(2-Chloroethyl)nitrosoamino]carbonyl]methylamino]cyclohexanecarboxylic acid, a nitrosourea with latent activity against an experimental solid tumor

Journal of medicinal chemistry, 1983, Vol.27 (1), p.97-99

1983

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ChemInform Abstract: CARCINOGENIC NITROSAMINES: HUNDRED‐GRAM PREPARATIONS OF N‐NITROSODIETHANOLAMINE AND α‐UREIDODIMETHYLNITROSAMINE

Chemischer Informationsdienst, 1984-09, Vol.15 (36)

1984

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ChemInform Abstract: Synthesis of 10‐Propargylfolic Acid from 2‐Amino‐6‐(bromomethyl)‐4‐ (1H)‐pteridinone

ChemInform, 1987-10, Vol.18 (42), p.no-no

1987

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THE SYNTHESIS OF ANTINEOPLASTIC AGENTS. XXXII. N-NITROSOUREAS. I

Journal of medicinal chemistry, 1963-11, Vol.6, p.669-681

1963

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A synthetic approach to poly(.gamma.-glutamyl) conjugates of methotrexate

Journal of medicinal chemistry, 1983-02, Vol.26 (2), p.291-294

1983

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ChemInform Abstract: A SYNTHETIC APPROACH TO POLY(Γ‐GLUTAMYL) CONJUGATES OF METHOTREXATE

Chemischer Informationsdienst, 1983-07, Vol.14 (28)

1983

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Synthesis and antifolate activity of 5-methyl-5,10-dideaza analogs of aminopterin and folic acid and an alternative synthesis of 5,10-dideazatetrahydrofolic acid, a potent inhibitor of glycinamide ribonucleotide formyltransferase

Syntheses and evaluation as antifolates of MTX analogs derived from 2,.omega.-diaminoalkanoic acids

Syntheses and antifolate activity of 5-methyl-5-deaza analogs of aminopterin, methotrexate, folic acid, and N10-methylfolic acid

10-Propargylaminopterin and alkyl homologs of methotrexate as inhibitors of folate metabolism

10-Propargylaminopterin and alkyl homologues of methotrexate as inhibitors of folate metabolism

Synthesis of chlorozotocin, the 2-chloroethyl analog of the anticancer antibiotic streptozotocin

Carcinogenic Nitrosamines: Hundred-Gram Preparations of N-Nitrosodiethanolamine and α-Ureidodimethylnitrosamine

Synthesis of 10-propargylfolic acid from 2-amino-6-(bromomethyl)-4(1h)-pteridinone

The Modes of Decomposition of 1,3-Bis(2-chloroethyl)-1-nitrosourea and Related Compounds

Decomposition of N-(2-chloroethyl)-N-nitrosoureas in aqueous media

cis-4-[[[(2-Chloroethyl)nitrosoamino]carbonyl]methylamino]cyclohexanecarboxylic acid, a nitrosourea with latent activity against an experimental solid tumor

Comparison of the properties of metabolites of CCNU

5-Substituted-5-Deaza Analogues of Classical Antifolates

Synthesis and biologic evaluation of major metabolites of N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea

Inhibition of solid tumors by nitrosoureas. 1. Lewis lung carcinoma

Synthesis of analogs of N-(2-chloroethyl)-N'-(trans-4-methylcyclohexyl)-N-nitrosourea for evaluation as anticancer agents

L-Chlorozotocin

A synthetic approach to poly(gamma-glutamyl) congugates of methotrexate

Syntheses and evaluation as antifolates of MTX analogues derived from 2,w-diaminoalkanoic acids

cis-4-[[[(2-Chloroethyl)nitrosoamino]carbonyl]methylamino]cyclohexanecarboxylic acid, a nitrosourea with latent activity against an experimental solid tumor

ChemInform Abstract: CARCINOGENIC NITROSAMINES: HUNDRED‐GRAM PREPARATIONS OF N‐NITROSODIETHANOLAMINE AND α‐UREIDODIMETHYLNITROSAMINE

ChemInform Abstract: Synthesis of 10‐Propargylfolic Acid from 2‐Amino‐6‐(bromomethyl)‐4‐ (1H)‐pteridinone

THE SYNTHESIS OF ANTINEOPLASTIC AGENTS. XXXII. N-NITROSOUREAS. I

A synthetic approach to poly(.gamma.-glutamyl) conjugates of methotrexate

ChemInform Abstract: A SYNTHETIC APPROACH TO POLY(Γ‐GLUTAMYL) CONJUGATES OF METHOTREXATE

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