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HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes

Nature communications, 2017-09, Vol.8 (1), p.451-8, Article 451

2017

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The RNA-binding Protein MEX3B Mediates Resistance to Cancer Immunotherapy by Downregulating HLA-A Expression

Clinical cancer research, 2018-07, Vol.24 (14), p.3366-3376

2018

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BRAF Inhibition Increases Tumor Infiltration by T cells and Enhances the Antitumor Activity of Adoptive Immunotherapy in Mice

Clinical cancer research, 2013-01, Vol.19 (2), p.393-403

2013

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The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy

JNCI : Journal of the National Cancer Institute, 2018-07, Vol.110 (7), p.777-786

2018

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Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies

Cell stem cell, 2024-09, Vol.31 (9), p.1376-1386.e8

2024

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Anti-OX40 Antibody Directly Enhances The Function of Tumor-Reactive CD8 + T Cells and Synergizes with PI3Kβ Inhibition in PTEN Loss Melanoma

Clinical cancer research, 2019-11, Vol.25 (21), p.6406-6416

2019

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Combined Genetic Ablation of CD54 and CD58 in CAR Engineered Cytotoxic Lymphocytes Effectively Averts Allogeneic Immune Cell Rejection

BLOOD, 2022-11, Vol.140 (Supplement 1), p.1165-1166

2022

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Integrating genome-wide CRISPR immune screen with multi-omic clinical data reveals distinct classes of tumor intrinsic immune regulators

Journal for immunotherapy of cancer, 2021-02, Vol.9 (2), p.e001819

2021

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Aurora kinase inhibition sensitizes melanoma cells to T-cell-mediated cytotoxicity

Cancer Immunology, Immunotherapy, 2021-04, Vol.70 (4), p.1101-1113

2021

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Abstract 4360: Inhibition of HSP90 enhances T cell-mediated antitumor immune responses through expression of interferon-alpha response Genes

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4360-4360

2016

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Abstract 4002: Enhancing the antitumor efficacy of immunotherapy by using the topoisomerase I inhibitor MM398

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4002-4002

2016

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554 The panorama of tumor intrinsic immune regulators exhibited by genome-wide CRPISR immune screen integrated with comprehensive clinical dataset analysis

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A584-A584

2021

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Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy

Cancer discovery, 2016-02, Vol.6 (2), p.202-216

2016

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iPSC-Derived CD38-Null NK Cells in Combination with CD38-Targeted Antibody: A Dual Therapeutic Strategy to Enable ADCC and Eliminate Host Immune Cells in Multiple Myeloma

Blood, 2022-11, Vol.140 (Supplement 1), p.7388-7389

2022

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Alloimmune Defense Receptor Harnesses Host Immune Cell Activation to Potentiate Functional Persistence and Anti-Tumor Activity of Off-the-Shelf, Cell-Based Cancer Therapy

Blood, 2022-11, Vol.140 (Supplement 1), p.4547-4548

2022

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Off-the-Shelf, iPSC-Derived CAR-NK Cells Multiplexed-Engineered for the Avoidance of Allogeneic Host Immune Cell Rejection

BLOOD, 2021-11, Vol.138 (Supplement 1), p.2795-2795

2021

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A Novel Stealth Strategy That Activates Adoptively Transferred Allogeneic Immune Cells and Avoids Rejection for Off-the-Shelf Cell-Based Cancer Therapy

BLOOD, 2021-11, Vol.138 (Supplement 1), p.4800-4800

2021

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Abstract 1575: The landscape of tumor intrinsic immune regulators revealed by genome-wide CRISPR immune screen integrated with comprehensive clinical data analysis

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1575-1575

2021

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Abstract 1441: Systems-level interrogation of resistance mechanisms to immunotherapy through pooled shRNA screens

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.1441-1441

2016

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Abstract 4010: Identification of novel targeted and immunotherapy combinations by a high throughput assay of T cell-mediated cytotoxicity

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4010-4010

2016

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Abstract 4938: OX40 agonist antibody-based combination therapy with PI3Kβ selective inhibitor enhances T cell immunity

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.4938-4938

2018

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Abstract IA19: Rational combinations of targeted and immunotherapies

Cancer immunology research, 2016-11, Vol.4 (11_Supplement), p.IA19-IA19

2016

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Abstract B152: Increasing the antitumor efficacy of immunotherapy in melanoma by using topoisomerase I inhibitors

Cancer immunology research, 2016-01, Vol.4 (1_Supplement), p.B152-B152

2016

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The metabolic basis of resistance to Adoptive T Cell Therapy (ACT) in patients with solid tumors

The Journal of immunology (1950), 2018-05, Vol.200 (1_Supplement), p.177-177.1

2018

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Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy

HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes

The RNA-binding Protein MEX3B Mediates Resistance to Cancer Immunotherapy by Downregulating HLA-A Expression

BRAF Inhibition Increases Tumor Infiltration by T cells and Enhances the Antitumor Activity of Adoptive Immunotherapy in Mice

The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy

Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies

Anti-OX40 Antibody Directly Enhances The Function of Tumor-Reactive CD8 + T Cells and Synergizes with PI3Kβ Inhibition in PTEN Loss Melanoma

Combined Genetic Ablation of CD54 and CD58 in CAR Engineered Cytotoxic Lymphocytes Effectively Averts Allogeneic Immune Cell Rejection

Integrating genome-wide CRISPR immune screen with multi-omic clinical data reveals distinct classes of tumor intrinsic immune regulators

Aurora kinase inhibition sensitizes melanoma cells to T-cell-mediated cytotoxicity

Abstract 4360: Inhibition of HSP90 enhances T cell-mediated antitumor immune responses through expression of interferon-alpha response Genes

Abstract 4002: Enhancing the antitumor efficacy of immunotherapy by using the topoisomerase I inhibitor MM398

554 The panorama of tumor intrinsic immune regulators exhibited by genome-wide CRPISR immune screen integrated with comprehensive clinical dataset analysis

Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy

iPSC-Derived CD38-Null NK Cells in Combination with CD38-Targeted Antibody: A Dual Therapeutic Strategy to Enable ADCC and Eliminate Host Immune Cells in Multiple Myeloma

Alloimmune Defense Receptor Harnesses Host Immune Cell Activation to Potentiate Functional Persistence and Anti-Tumor Activity of Off-the-Shelf, Cell-Based Cancer Therapy

Off-the-Shelf, iPSC-Derived CAR-NK Cells Multiplexed-Engineered for the Avoidance of Allogeneic Host Immune Cell Rejection

A Novel Stealth Strategy That Activates Adoptively Transferred Allogeneic Immune Cells and Avoids Rejection for Off-the-Shelf Cell-Based Cancer Therapy

Abstract 1575: The landscape of tumor intrinsic immune regulators revealed by genome-wide CRISPR immune screen integrated with comprehensive clinical data analysis

Abstract 1441: Systems-level interrogation of resistance mechanisms to immunotherapy through pooled shRNA screens

Abstract 4010: Identification of novel targeted and immunotherapy combinations by a high throughput assay of T cell-mediated cytotoxicity

Abstract 4938: OX40 agonist antibody-based combination therapy with PI3Kβ selective inhibitor enhances T cell immunity

Abstract IA19: Rational combinations of targeted and immunotherapies

Abstract B152: Increasing the antitumor efficacy of immunotherapy in melanoma by using topoisomerase I inhibitors

The metabolic basis of resistance to Adoptive T Cell Therapy (ACT) in patients with solid tumors

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