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Design and Validation of Bicyclic Iminopyrimidinones As Beta Amyloid Cleaving Enzyme‑1 (BACE1) Inhibitors: Conformational Constraint to Favor a Bioactive Conformation

Journal of medicinal chemistry, 2012-11, Vol.55 (21), p.9331-9345

2012

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Generation of Leads for γ‑Secretase Modulation

Journal of medicinal chemistry, 2020-08, Vol.63 (15), p.8216-8230

2020

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Stereoselective Nazarov Cyclizations of Bridged Bicyclic Dienones

Organic letters, 2005-06, Vol.7 (13), p.2799-2801

2005

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Discovery of novel hydroxamates as highly potent tumor necrosis factor-α converting enzyme inhibitors. Part II: Optimization of the S3′ pocket

Bioorganic & medicinal chemistry, 2008-11, Vol.18 (21), p.5809-5814

2008

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Unexpected Participation of an Unconjugated Olefin during Nazarov Cyclization of Bridged Bicyclic Dienones

Angewandte Chemie (International ed.), 2005-10, Vol.44 (40), p.6546-6549

2005

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Overcoming Time-Dependent Inhibition (TDI) of Cytochrome P450 3A4 (CYP3A4) Resulting from Bioactivation of a Fluoropyrimidine Moiety

Journal of medicinal chemistry, 2018-12, Vol.61 (23), p.10700-10708

2018

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Discovery of new SCH 39166 analogs as potent and selective dopamine D1 receptor antagonists

Bioorganic & medicinal chemistry letters, 2010-02, Vol.20 (3), p.836-840

2010

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Discovery of potent iminoheterocycle BACE1 inhibitors

Bioorganic & medicinal chemistry letters, 2014-12, Vol.24 (23), p.5455-5459

2014

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Iminoheterocycles as γ-secretase modulators

Bioorganic & medicinal chemistry letters, 2010-09, Vol.20 (18), p.5380-5384

2010

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Unexpected Participation of an Unconjugated Olefin during Nazarov Cyclization of Bridged Bicyclic Dienones

Angewandte Chemie, 2005-10, Vol.117 (40), p.6704-6707

2005

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Discovery of new SCH 39166 analogs as potent and selective dopamine D 1 receptor antagonists

Bioorganic & medicinal chemistry letters, 2010-02, Vol.20 (3), p.836-840

2010

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Discovery of new SCH 39166 analogs as potent and selective dopamine D sub(1) receptor antagonists

Bioorganic & medicinal chemistry letters, 2010-02, Vol.20 (3), p.836-840

2010

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Iminoheterocycles as g-secretase modulators

Bioorganic & medicinal chemistry letters, 2010-09, Vol.20 (18), p.5380-5384

2010

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Unexpected Participation of an Unconjugated Olefin during Nazarov Cyclization of Bridged Bicyclic Dienones

Angewandte Chemie, 2005-10, Vol.117 (40), p.6704-6707

2005

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Discovery of novel hydroxamates as highly potent tumor necrosis factor-a converting enzyme inhibitors. Part II: Optimization of the S3' pocket

Bioorganic & medicinal chemistry letters, 2008, Vol.18 (21), p.5809-5814

2008

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Discovery of novel hydroxamates as highly potent tumor necrosis factor-[alpha] converting enzyme inhibitors. Part II: Optimization of the S3′ pocket

Bioorganic & medicinal chemistry letters, 2010-10, Vol.18 ((21) ; 11, 2008)

2010

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Torquoselectivity in the Nazarov cyclization of facially biased dienones and their application toward total synthesis of taxinine

Mazzola, Robert D

2001

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Development and validation of a spontaneous preterm delivery predictor in asymptomatic women

American journal of obstetrics and gynecology, 2016-05, Vol.214 (5), p.633.e1-633.e24

2016

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Elucidation and partial NMR assignment of monosulfated maitotoxins from the Caribbean

Toxicon (Oxford), 2019-06, Vol.164, p.44-50

2019

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Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors

Cancer research (Chicago, Ill.), 2002-12, Vol.62 (23), p.6831-6836

2002

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case study of chlorine transport and fate following a large accidental release

Atmospheric environment (1994), 2012-12, Vol.62, p.184-198

2012

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Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level

The New England journal of medicine, 2019-05, Vol.380 (21), p.2009-2019

2019

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Contributions to the Neurosurgery Political Action Committee (NeurosurgeryPAC): A Historical Perspective

World neurosurgery, 2020-03, Vol.135, p.273-279

2020

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Methodology for Characterization of Common-Mode Conducted Electromagnetic Emissions in Wide-Bandgap Converters for Ungrounded Shipboard Applications

IEEE journal of emerging and selected topics in power electronics, 2018-03, Vol.6 (1), p.300-314

2018

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Design and Validation of Bicyclic Iminopyrimidinones As Beta Amyloid Cleaving Enzyme‑1 (BACE1) Inhibitors: Conformational Constraint to Favor a Bioactive Conformation

Generation of Leads for γ‑Secretase Modulation

Stereoselective Nazarov Cyclizations of Bridged Bicyclic Dienones

Discovery of novel hydroxamates as highly potent tumor necrosis factor-α converting enzyme inhibitors. Part II: Optimization of the S3′ pocket

Unexpected Participation of an Unconjugated Olefin during Nazarov Cyclization of Bridged Bicyclic Dienones

Structure-Based Design of an Iminoheterocyclic β‑Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in Nonhuman Primates

Overcoming Time-Dependent Inhibition (TDI) of Cytochrome P450 3A4 (CYP3A4) Resulting from Bioactivation of a Fluoropyrimidine Moiety

Discovery of new SCH 39166 analogs as potent and selective dopamine D1 receptor antagonists

Discovery of potent iminoheterocycle BACE1 inhibitors

Iminoheterocycles as γ-secretase modulators

Unexpected Participation of an Unconjugated Olefin during Nazarov Cyclization of Bridged Bicyclic Dienones

Discovery of new SCH 39166 analogs as potent and selective dopamine D 1 receptor antagonists

Discovery of new SCH 39166 analogs as potent and selective dopamine D sub(1) receptor antagonists

Iminoheterocycles as g-secretase modulators

Unexpected Participation of an Unconjugated Olefin during Nazarov Cyclization of Bridged Bicyclic Dienones

Discovery of novel hydroxamates as highly potent tumor necrosis factor-a converting enzyme inhibitors. Part II: Optimization of the S3' pocket

Discovery of novel hydroxamates as highly potent tumor necrosis factor-[alpha] converting enzyme inhibitors. Part II: Optimization of the S3′ pocket

Torquoselectivity in the Nazarov cyclization of facially biased dienones and their application toward total synthesis of taxinine

Development and validation of a spontaneous preterm delivery predictor in asymptomatic women

Elucidation and partial NMR assignment of monosulfated maitotoxins from the Caribbean

Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors

case study of chlorine transport and fate following a large accidental release

Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level

Contributions to the Neurosurgery Political Action Committee (NeurosurgeryPAC): A Historical Perspective

Methodology for Characterization of Common-Mode Conducted Electromagnetic Emissions in Wide-Bandgap Converters for Ungrounded Shipboard Applications

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