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Mismatch repair deficiency predicts response to HER2 blockade in HER2-negative breast cancer

Nature communications, 2021-05, Vol.12 (1), p.2940-11, Article 2940

2021

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Tetrahydrobenzimidazole TMQ0153 triggers apoptosis, autophagy and necroptosis crosstalk in chronic myeloid leukemia

Cell death & disease, 2020-02, Vol.11 (2), p.109, Article 109

2020

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The DNA damage repair landscape in Black women with breast cancer

Therapeutic advances in medical oncology, 2022-02, Vol.14, p.17588359221075458-17588359221075458

2022

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Discovery and characterization of Isofistularin-3, a marine brominated alkaloid, as a new DNA demethylating agent inducing cell cycle arrest and sensitization to TRAIL in cancer cells

Oncotarget, 2016-04, Vol.7 (17), p.24027-24049

2016

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Dual inhibition of sirtuins 1 and 2: reprogramming metabolic energy dynamics in chronic myeloid leukemia as an immunogenic anticancer strategy

Cancer communications (London, England), 2024-08, Vol.44 (8), p.915-920

2024

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Raloxifene Suppresses Tumor Growth and Metastasis in an Orthotopic Model of Castration-Resistant Prostate Cancer

Biomedicines, 2022-04, Vol.10 (4), p.853

2022

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Cardiac Glycoside Glucoevatromonoside Induces Cancer Type-Specific Cell Death

Frontiers in pharmacology, 2018-03, Vol.9, p.70-70

2018

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Natural scaffolds in anticancer therapy and precision medicine

Biotechnology advances, 2018-11, Vol.36 (6), p.1563-1585

2018

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Abstract A015: Mutations in mismatch repair genes that alter subcellular localization of the protein predict resistance to standard therapy but response to cell cycle inhibitors

Cancer research (Chicago, Ill.), 2024-02, Vol.84 (3_Supplement_1), p.A015-A015

2024

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HER2 Activation and Endocrine Treatment Resistance in HER2-negative Breast Cancer

Endocrinology (Philadelphia), 2021-10, Vol.162 (10), p.1

2021

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Abstract PO-090: Coordinate dysregulation of base excision repair and homologous recombination pathways predominates in ER+/HER2- breast tumors from African American patients, and associates with worse disease-specific outcomes

Cancer epidemiology, biomarkers & prevention, 2020-12, Vol.29 (12_Supplement), p.PO-090-PO-090

2020

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Abstract 23: Using mutations in mismatch repair genes to predict response to palbociclib

Clinical cancer research, 2020-06, Vol.26 (12_Supplement_1), p.23-23

2020

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Abstract 2521: Race specific differences in DNA damage repair dysregulation in breast cancer and association with outcome

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.2521-2521

2021

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Abstract P3-14-03: The DNA damage repair landscape in Black women with breast cancer

Cancer research (Chicago, Ill.), 2022-02, Vol.82 (4_Supplement), p.P3-P3-14-03

2022

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Abstract 5129: Subcellular MLH1 protein as first in class biomarker for CDK4/6 response in endocrine resistant ER+/HER2- breast cancer

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.5129-5129

2024

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Human telomerase reverse transcriptase depletion potentiates the growth-inhibitory activity of imatinib in chronic myeloid leukemia stem cells

Cancer letters, 2020-01, Vol.469, p.468-480

2020

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Preclinical Assessment of the Bioactivity of the Anticancer Coumarin OT48 by Spheroids, Colony Formation Assays, and Zebrafish Xenografts

Journal of visualized experiments, 2018-06 (136)

2018

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4-Hydroxybenzoic acid derivatives as HDAC6-specific inhibitors modulating microtubular structure and HSP90α chaperone activity against prostate cancer

Biochemical pharmacology, 2016-01, Vol.99, p.31-52

2016

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Preclinical Assessment of the Bioactivity of the Anticancer Coumarin OT48 by Spheroids, Colony Formation Assays, and Zebrafish Xenografts

Journal of visualized experiments, 2018-06 (136)

2018

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Abstract PD8-05: Mismatch repair deficiency predicts response to HER2 blockade in HER2-negative breast cancer

Cancer research (Chicago, Ill.), 2021-02, Vol.81 (4_Supplement), p.PD8-05-PD8-05

2021

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The HDAC6 inhibitor 7b induces BCR-ABL ubiquitination and downregulation and synergizes with imatinib to trigger apoptosis in chronic myeloid leukemia

Pharmacological research, 2020-10, Vol.160, p.105058-105058, Article 105058

2020

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Discovery and Characterization of R/S‑N‑3-Cyanophenyl‑N′‑(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl‑2H‑1-benzopyran-4-yl)urea, a New Histone Deacetylase Class III Inhibitor Exerting Antiproliferative Activity against Cancer Cell Lines

Journal of medicinal chemistry, 2017-06, Vol.60 (11), p.4714-4733

2017

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Hydroxycoumarin OT-55 kills CML cells alone or in synergy with imatinib or Synribo: Involvement of ER stress and DAMP release

Cancer letters, 2018-12, Vol.438, p.197-218

2018

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Abstract P3-10-02: Cell cycle dysregulation in breast cancer: why the details matter

Cancer research (Chicago, Ill.), 2023-03, Vol.83 (5_Supplement), p.P3-P3-10-02

2023

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The dialkyl resorcinol stemphol disrupts calcium homeostasis to trigger programmed immunogenic necrosis in cancer

Cancer letters, 2018-03, Vol.416, p.109-123

2018

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Mismatch repair deficiency predicts response to HER2 blockade in HER2-negative breast cancer

Tetrahydrobenzimidazole TMQ0153 triggers apoptosis, autophagy and necroptosis crosstalk in chronic myeloid leukemia

The DNA damage repair landscape in Black women with breast cancer

Discovery and characterization of Isofistularin-3, a marine brominated alkaloid, as a new DNA demethylating agent inducing cell cycle arrest and sensitization to TRAIL in cancer cells

Dual inhibition of sirtuins 1 and 2: reprogramming metabolic energy dynamics in chronic myeloid leukemia as an immunogenic anticancer strategy

Raloxifene Suppresses Tumor Growth and Metastasis in an Orthotopic Model of Castration-Resistant Prostate Cancer

Cardiac Glycoside Glucoevatromonoside Induces Cancer Type-Specific Cell Death

Natural scaffolds in anticancer therapy and precision medicine

Abstract A015: Mutations in mismatch repair genes that alter subcellular localization of the protein predict resistance to standard therapy but response to cell cycle inhibitors

HER2 Activation and Endocrine Treatment Resistance in HER2-negative Breast Cancer

Abstract PO-090: Coordinate dysregulation of base excision repair and homologous recombination pathways predominates in ER+/HER2- breast tumors from African American patients, and associates with worse disease-specific outcomes

Abstract 23: Using mutations in mismatch repair genes to predict response to palbociclib

Abstract 2521: Race specific differences in DNA damage repair dysregulation in breast cancer and association with outcome

Abstract P3-14-03: The DNA damage repair landscape in Black women with breast cancer

Abstract 5129: Subcellular MLH1 protein as first in class biomarker for CDK4/6 response in endocrine resistant ER+/HER2- breast cancer

Human telomerase reverse transcriptase depletion potentiates the growth-inhibitory activity of imatinib in chronic myeloid leukemia stem cells

Preclinical Assessment of the Bioactivity of the Anticancer Coumarin OT48 by Spheroids, Colony Formation Assays, and Zebrafish Xenografts

4-Hydroxybenzoic acid derivatives as HDAC6-specific inhibitors modulating microtubular structure and HSP90α chaperone activity against prostate cancer

Preclinical Assessment of the Bioactivity of the Anticancer Coumarin OT48 by Spheroids, Colony Formation Assays, and Zebrafish Xenografts

Abstract PD8-05: Mismatch repair deficiency predicts response to HER2 blockade in HER2-negative breast cancer

The HDAC6 inhibitor 7b induces BCR-ABL ubiquitination and downregulation and synergizes with imatinib to trigger apoptosis in chronic myeloid leukemia

Discovery and Characterization of R/S‑N‑3-Cyanophenyl‑N′‑(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl‑2H‑1-benzopyran-4-yl)urea, a New Histone Deacetylase Class III Inhibitor Exerting Antiproliferative Activity against Cancer Cell Lines

Hydroxycoumarin OT-55 kills CML cells alone or in synergy with imatinib or Synribo: Involvement of ER stress and DAMP release

Abstract P3-10-02: Cell cycle dysregulation in breast cancer: why the details matter

The dialkyl resorcinol stemphol disrupts calcium homeostasis to trigger programmed immunogenic necrosis in cancer

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