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A rationale for determining, testing, and controlling specific impurities in pharmaceuticals that possess potential for genotoxicity

Regulatory toxicology and pharmacology, 2006-04, Vol.44 (3), p.198-211

2006

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An organizational approach for the assessment of DNA adduct data in risk assessment: case studies for aflatoxin B1, tamoxifen and vinyl chloride

Critical reviews in toxicology, 2014-04, Vol.44 (4), p.348-391

2014

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Effects of Lersivirine on Canine and Rodent Thyroid Function

Toxicologic pathology, 2014-07, Vol.42 (5), p.897-912

2014

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SFTG international collaborative study on in vitro micronucleus test III. Using CHO cells

Mutation research, 2006-08, Vol.607 (1), p.61-87

2006

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Genetic Toxicity Assessment: Employing the Best Science for Human Safety Evaluation Part VII: Why Not Start with a Single Test: A Transformational Alternative to Genotoxicity Hazard and Risk Assessment

Toxicological sciences, 2007-09, Vol.99 (1), p.20-25

2007

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A preliminary evaluation of accelerator mass spectrometry in the biomedical field

Journal of pharmaceutical and biomedical analysis, 1997-11, Vol.16 (3), p.541-543

1997

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SFTG international collaborative study on in vitro micronucleus test

Mutation research. Genetic toxicology and environmental mutagenesis, 2006-08, Vol.607 (1), p.61-87

2006

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Exposure of mammalian cell cultures to benzo[a] and light results in oxidative DNA damage as measured by 8-hydroxydeoxyguanosine formation

Carcinogenesis (New York), 1995-01, Vol.16 (1), p.133-137

1995

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Distribution and metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in female rats and their pups at dietary doses

Carcinogenesis (New York), 1998-05, Vol.19 (5), p.919-924

1998

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Limits of genotoxic impurities in medicines—a threshold and pragmatic approach

Toxicology (Amsterdam), 2006-09, Vol.226 (1), p.29-29

Mauthe, Robert J.

2006

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An organizational approach for the assessment of DNA adduct data in risk assessment: case studies for aflatoxin B 1 , tamoxifen and vinyl chloride

Critical reviews in toxicology, 2014-04, Vol.44 (4), p.348-391

2014

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The capability of rat colon tissue slices to metabolize the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

Cancer research (Chicago, Ill.), 1996-06, Vol.56 (11), p.2550-2555

1996

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Comparisons of the binding of [ 14C]radiolabelled tamoxifen or toremifene to rat DNA using accelerator mass spectrometry

Chemico-biological interactions, 1997-09, Vol.106 (2), p.149-160

1997

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Comparison of DNA‐adduct and tissue‐available dose levels of MeIQx in human and rodent colon following administration of a very low dose

International journal of cancer, 1999-02, Vol.80 (4), p.539-545

1999

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Interspecies differences in the major DNA adducts formed from benzo(a)pyrene but not 7,12-dimethylbenz(a)anthracene in rat and human mammary cell cultures

Cancer research (Chicago, Ill.), 1987-08, Vol.47 (16), p.4402-4406

1987

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Investigation of the formation and accumulation of liver DNA adducts in mice chronically exposed to tamoxifen

Carcinogenesis (New York), 1997-11, Vol.18 (11), p.2209-2215

1997

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MeIQx-DNA adduct formation in rodent and human tissues at low doses

Mutation research, 1997-05, Vol.376 (1), p.243-252

1997

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SFTG international collaborative study on in vitro micronucleus test III. Using CHO cells: SFTG international collaborative study on in vitro micronucleus test

Mutation research. Genetic toxicology and environmental mutagenesis, 2006, Vol.607 (1), p.61-87

2006

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Pyrethroid Decrease in Central Nervous System from Nerve Agent Pretreatment

Journal of applied toxicology, 1997-07, Vol.17 (4), p.231-234

1997

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Quantitation of benzo[ a]pyrene-DNA adducts by postlabeling with 14C-acetic anhydride and accelerator mass spectrometry

Chemico-biological interactions, 2000-06, Vol.126 (3), p.171-183

2000

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Instability of (±)-7β, 8α-dihydroxy-9β, 10β-epoxy-7, 8, 9, 10-tetrahydrobenzo[a]pyrene (syn-BaPDE)- DNA adducts formed in benzo[a]pyrene-treated Wistar rat embryo cell cultures

Carcinogenesis (New York), 1988-10, Vol.9 (10), p.1863-1868

1988

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Analysis of the Fine Structure of the Repair of Anti−benzo[a]pyrene-7,8-diol-9,10-epoxide-DNA Adducts in Mammalian Cells by Laser-Induced Strand Cleavage

Polycyclic aromatic compounds, 1994-08, Vol.6 (1-4), p.169-176

1994

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Improved high-performance liquid chromatography analysis of 32P-postlabeled 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine-DNA adducts using in-line precolumn purification

Journal of chromatography. Biomedical applications, 1996-04, Vol.679 (1), p.91-101

1996

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Predicting discharge destination of stroke patients using a mathematical model based on six items from the functional independence measure

Archives of physical medicine and rehabilitation, 1996, Vol.77 (1), p.10-13

1996

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THE EFFECT OF SMOKING ON IMPLANT SURVIVAL AT SECOND-STAGE SURGERY: DICRG INTERIM REPROT NO. 5

Implant dentistry, 1994, Vol.3 (3), p.165

1994

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A rationale for determining, testing, and controlling specific impurities in pharmaceuticals that possess potential for genotoxicity

An organizational approach for the assessment of DNA adduct data in risk assessment: case studies for aflatoxin B1, tamoxifen and vinyl chloride

Effects of Lersivirine on Canine and Rodent Thyroid Function

SFTG international collaborative study on in vitro micronucleus test III. Using CHO cells

Genetic Toxicity Assessment: Employing the Best Science for Human Safety Evaluation Part VII: Why Not Start with a Single Test: A Transformational Alternative to Genotoxicity Hazard and Risk Assessment

A preliminary evaluation of accelerator mass spectrometry in the biomedical field

SFTG international collaborative study on in vitro micronucleus test

Exposure of mammalian cell cultures to benzo[a] and light results in oxidative DNA damage as measured by 8-hydroxydeoxyguanosine formation

Distribution and metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in female rats and their pups at dietary doses

Limits of genotoxic impurities in medicines—a threshold and pragmatic approach

An organizational approach for the assessment of DNA adduct data in risk assessment: case studies for aflatoxin B 1 , tamoxifen and vinyl chloride

The capability of rat colon tissue slices to metabolize the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine

Comparisons of the binding of [ 14C]radiolabelled tamoxifen or toremifene to rat DNA using accelerator mass spectrometry

Comparison of DNA‐adduct and tissue‐available dose levels of MeIQx in human and rodent colon following administration of a very low dose

Interspecies differences in the major DNA adducts formed from benzo(a)pyrene but not 7,12-dimethylbenz(a)anthracene in rat and human mammary cell cultures

Investigation of the formation and accumulation of liver DNA adducts in mice chronically exposed to tamoxifen

MeIQx-DNA adduct formation in rodent and human tissues at low doses

SFTG international collaborative study on in vitro micronucleus test III. Using CHO cells: SFTG international collaborative study on in vitro micronucleus test

Pyrethroid Decrease in Central Nervous System from Nerve Agent Pretreatment

Quantitation of benzo[ a]pyrene-DNA adducts by postlabeling with 14C-acetic anhydride and accelerator mass spectrometry

Instability of (±)-7β, 8α-dihydroxy-9β, 10β-epoxy-7, 8, 9, 10-tetrahydrobenzo[a]pyrene (syn-BaPDE)- DNA adducts formed in benzo[a]pyrene-treated Wistar rat embryo cell cultures

Analysis of the Fine Structure of the Repair of Anti−benzo[a]pyrene-7,8-diol-9,10-epoxide-DNA Adducts in Mammalian Cells by Laser-Induced Strand Cleavage

Improved high-performance liquid chromatography analysis of 32P-postlabeled 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine-DNA adducts using in-line precolumn purification

Predicting discharge destination of stroke patients using a mathematical model based on six items from the functional independence measure

THE EFFECT OF SMOKING ON IMPLANT SURVIVAL AT SECOND-STAGE SURGERY: DICRG INTERIM REPROT NO. 5

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