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The Phosphatidylinositol 3-Kinase-Akt Pathway Limits Lipopolysaccharide Activation of Signaling Pathways and Expression of Inflammatory Mediators in Human Monocytic Cells

The Journal of biological chemistry, 2002-08, Vol.277 (35), p.32124-32132

2002

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LPS induction of gene expression in human monocytes

Cellular Signalling, 2001-02, Vol.13 (2), p.85-94

2001

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The impact of dasatinib on pregnancy outcomes

American journal of hematology, 2015-12, Vol.90 (12), p.1111-1115

2015

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Clinical features of pulmonary arterial hypertension in patients receiving dasatinib

American journal of hematology, 2015-11, Vol.90 (11), p.1060-1064

2015

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Specific down-regulation of connective tissue growth factor attenuates progression of nephropathy in mouse models of type 1 and type 2 diabetes

The FASEB journal, 2007-10, Vol.21 (12), p.3355-3368

2007

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High Glucose-Induced Expression of Proinflammatory Cytokine and Chemokine Genes in Monocytic Cells

Diabetes (New York, N.Y.), 2003-05, Vol.52 (5), p.1256-1264

2003

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In vitro and in vivo evaluation of dasatinib and imatinib on physiological parameters of pulmonary arterial hypertension

Cancer chemotherapy and pharmacology, 2017-04, Vol.79 (4), p.711-723

2017

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Improved ruggedness of an ion-pairing liquid chromatography/tandem mass spectrometry assay for the quantitative analysis of the triphosphate metabolite of a nucleoside reverse transcriptase inhibitor in peripheral blood mononuclear cells

Rapid communications in mass spectrometry, 2013-02, Vol.27 (3), p.481-488

2013

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Inhaled CD86 antisense oligonucleotide suppresses pulmonary inflammation and airway hyper-responsiveness in allergic mice

The Journal of pharmacology and experimental therapeutics, 2007-06, Vol.321 (3), p.938-946

2007

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Enzalutamide and Apalutamide: In Vitro Chemical Reactivity Studies and Activity in a Mouse Drug Allergy Model

Chemical research in toxicology, 2020-01, Vol.33 (1), p.211-222

2020

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Dexamethasone enhances LPS induction of tissue factor expression in human monocytic cells by increasing tissue factor mRNA stability

Journal of leukocyte biology, 2004-07, Vol.76 (1), p.145-151

2004

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Comparative Analyses of Poly(ADP-Ribose) Polymerase Inhibitors

International journal of toxicology, 2022-12, Vol.41 (6), p.442-454

2022

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Discovery of MDV6058 (PF-06952229), a selective and potent TGFβR1 inhibitor: Design, synthesis and optimization

Bioorganic & medicinal chemistry letters, 2022-11, Vol.75, p.128979-128979, Article 128979

2022

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Salt Selection Matters: Differential Renal Toxicity With MDV1634.Maleate Versus MDV1634.2HCl

International journal of toxicology, 2017-05, Vol.36 (3), p.207-219

2017

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Molecular Mechanisms of Tumor Necrosis Factor α Gene Expression in Monocytic Cells via Hyperglycemia-induced Oxidant Stress-dependent and -independent Pathways

The Journal of biological chemistry, 2000-06, Vol.275 (23), p.17728-17739

2000

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Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor α expression by inducing Elk-1 phosphorylation and Egr-1 expression

Blood, 2001-09, Vol.98 (5), p.1429-1439

2001

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Corrigendum to “LPS induction of gene expression in human monocytes” [Cell. Signall. 13 (2001) 85–94]

Cellular signalling, 2006-04, Vol.18 (4), p.e2-e2

2006

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Abstract 2426: In vitro and in vivo evaluation of dasatinib and imatinib on physiological parameters of pulmonary arterial hypertension

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.2426-2426

2013

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Assessment of biomarkers of drug-induced kidney injury in cynomolgus monkeys treated with a triple reuptake inhibitor

Toxicological sciences, 2011-04, Vol.120 (2), p.269-283

2011

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Anti-inflammatory activity of inhaled IL-4 receptor-alpha antisense oligonucleotide in mice

American journal of respiratory cell and molecular biology, 2007-03, Vol.36 (3), p.276-285

2007

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Synthesis and SAR of 2-aryl-3-aminomethylquinolines as agonists of the bile acid receptor TGR5

Bioorganic & medicinal chemistry letters, 2010-10, Vol.20 (19), p.5718-5721

2010

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Regulation of tissue factor and inflammatory mediators by Egr-1 in a mouse endotoxemia model

Blood, 2003-05, Vol.101 (10), p.3940-3947

2003

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Nonclinical Safety Profile of BMS-986001, a Nucleoside Transcriptase Inhibitor for Combination Retroviral Therapy

International journal of toxicology, 2014-05, Vol.33 (3), p.204-218

2014

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Anti-Inflammatory Activity of Inhaled IL-4 Receptor-{alpha} Antisense Oligonucleotide in Mice

American journal of respiratory cell and molecular biology, 2007-03, Vol.36 (3), p.276

2007

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Transduction of Primitive Human Marrow and Cord Blood-Derived Hematopoietic Progenitor Cells With Adeno-Associated Virus Vectors

Blood, 1999-03, Vol.93 (6), p.1882-1894

1999

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The Phosphatidylinositol 3-Kinase-Akt Pathway Limits Lipopolysaccharide Activation of Signaling Pathways and Expression of Inflammatory Mediators in Human Monocytic Cells

LPS induction of gene expression in human monocytes

The impact of dasatinib on pregnancy outcomes

Clinical features of pulmonary arterial hypertension in patients receiving dasatinib

Specific down-regulation of connective tissue growth factor attenuates progression of nephropathy in mouse models of type 1 and type 2 diabetes

High Glucose-Induced Expression of Proinflammatory Cytokine and Chemokine Genes in Monocytic Cells

In vitro and in vivo evaluation of dasatinib and imatinib on physiological parameters of pulmonary arterial hypertension

Improved ruggedness of an ion-pairing liquid chromatography/tandem mass spectrometry assay for the quantitative analysis of the triphosphate metabolite of a nucleoside reverse transcriptase inhibitor in peripheral blood mononuclear cells

Inhaled CD86 antisense oligonucleotide suppresses pulmonary inflammation and airway hyper-responsiveness in allergic mice

Enzalutamide and Apalutamide: In Vitro Chemical Reactivity Studies and Activity in a Mouse Drug Allergy Model

Dexamethasone enhances LPS induction of tissue factor expression in human monocytic cells by increasing tissue factor mRNA stability

Comparative Analyses of Poly(ADP-Ribose) Polymerase Inhibitors

Discovery of MDV6058 (PF-06952229), a selective and potent TGFβR1 inhibitor: Design, synthesis and optimization

Salt Selection Matters: Differential Renal Toxicity With MDV1634.Maleate Versus MDV1634.2HCl

Molecular Mechanisms of Tumor Necrosis Factor α Gene Expression in Monocytic Cells via Hyperglycemia-induced Oxidant Stress-dependent and -independent Pathways

Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor α expression by inducing Elk-1 phosphorylation and Egr-1 expression

Corrigendum to “LPS induction of gene expression in human monocytes” [Cell. Signall. 13 (2001) 85–94]

Abstract 2426: In vitro and in vivo evaluation of dasatinib and imatinib on physiological parameters of pulmonary arterial hypertension

Assessment of biomarkers of drug-induced kidney injury in cynomolgus monkeys treated with a triple reuptake inhibitor

Anti-inflammatory activity of inhaled IL-4 receptor-alpha antisense oligonucleotide in mice

Synthesis and SAR of 2-aryl-3-aminomethylquinolines as agonists of the bile acid receptor TGR5

Regulation of tissue factor and inflammatory mediators by Egr-1 in a mouse endotoxemia model

Nonclinical Safety Profile of BMS-986001, a Nucleoside Transcriptase Inhibitor for Combination Retroviral Therapy

Anti-Inflammatory Activity of Inhaled IL-4 Receptor-{alpha} Antisense Oligonucleotide in Mice

Transduction of Primitive Human Marrow and Cord Blood-Derived Hematopoietic Progenitor Cells With Adeno-Associated Virus Vectors

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