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Design, synthesis and preliminary biological evaluations of novel amphiphilic drug carriers

Bioorganic & medicinal chemistry letters, 2006-03, Vol.16 (5), p.1111-1114

2006

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New Quaternary Ammonium Oxicam Derivatives Targeted toward Cartilage: Synthesis, Pharmacokinetic Studies, and Antiinflammatory Potency

Journal of medicinal chemistry, 1999-12, Vol.42 (25), p.5235-5240

1999

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Synthesis and in Vitro Evaluation of Quaternary Ammonium Derivatives of Chlorambucil and Melphalan, Anticancer Drugs Designed for the Chemotherapy of Chondrosarcoma

Journal of medicinal chemistry, 2002-05, Vol.45 (10), p.2116-2119

2002

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Cytotoxic effects of kinetin riboside on mouse, human and plant tumour cells

International journal of biological macromolecules, 2004-08, Vol.34 (4), p.271-275

2004

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Synthesis of N-quaternary ammonium [3H] and [99mTc]polyazamacrocycles, potential radiotracers for cartilage imaging

Journal of labelled compounds & radiopharmaceuticals, 2000-05, Vol.43 (6), p.585-594

2000

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Synthesis and pharmacokinetic profile of a quaternary ammonium derivative of chlorambucil, a potential anticancer drug for the chemotherapy of chondrosarcoma

Bioorganic & medicinal chemistry, 2003-11, Vol.11 (23), p.5007-5012

2003

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Quantification of BRCA1 protein in sporadic breast carcinoma with or without loss of heterozygosity of the BRCA1 gene

International journal of cancer, 1999-03, Vol.80 (6), p.823-826

1999

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Synthesis and in Vivo Biodisposition of [14C]-Quaternary Ammonium−Melphalan Conjugate, a Potential Cartilage-Targeted Alkylating Drug

Bioconjugate chemistry, 2003-03, Vol.14 (2), p.500-506

2003

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Presence of BRCA1 and BRCA2 proteins in human milk fat globules after delivery

Biochimica et biophysica acta, 2002-01, Vol.1586 (1), p.50-56

2002

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Synthesis and surface-active properties of glycosyl carbamates and thioureas

Carbohydrate research, 1999-09, Vol.321 (1), p.4-14

1999

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Synthesis of 4-tert-butyl-3-(2-chloro -[-2-14C]ethyl)ureido benzene

Journal of labelled compounds & radiopharmaceuticals, 1997-07, Vol.39 (7), p.559-566

1997

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Cross‐reaction between antibodies raised against the last 20 C‐terminal amino acids of BRCA 1 (C‐20) and human EGF and EGF‐R in MCF 10a human mammary epithelial cell line

International journal of cancer, 1997-03, Vol.71 (1), p.123-126

1997

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Disposition and metabolism of a novel antineoplastic agent, 4-tert-butyl-[3-(2-chloroethyl)ureido]benzene, in mice

Drug metabolism and disposition, 1998-02, Vol.26 (2), p.146

1998

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Synthesis of new cotelomers derived from tris(hydroxymethyl) aminomethane bearing arabinofuranosylcytosine moieties. Preliminary results on their in vitro and in vivo antitumoral activities

European journal of medicinal chemistry, 1998, Vol.33 (10), p.809-816

1998

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O6-(Alkyl/aralkyl)guanosine and 2‘-Deoxyguanosine Derivatives: Synthesis and Ability To Enhance Chloroethylnitrosourea Antitumor Action

Journal of medicinal chemistry, 1997-08, Vol.40 (18), p.2902-2909

1997

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Synthesis of carbon-14 labelled (3-{[(Z)-5-chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-1H-indol-1-yle]carbonylamino}propyl)trimethylammonium chloride, a potential cartilage-targeted antirheumatic drug

Journal of labelled compounds & radiopharmaceuticals, 2000-03, Vol.43 (3), p.297-308

2000

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Determination of BRCA2 oncosuppressor protein expression in human mammary cells by affinity perfusion high-performance chromatography

Journal of biochemical and biophysical methods, 2001-10, Vol.49 (1), p.657-663

2001

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Application to a cartilage targeting strategy: synthesis and in vivo biodistribution of (14)C-labeled quaternary ammonium-glucosamine conjugates

Bioconjugate chemistry, 2000-03, Vol.11 (2), p.212-218

2000

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Potentiation of the apoptotic effect of chloroethylnitrosoureas by a new O 6-alkylguanine-DNA alkyltransferase inhibitor

Biology of the cell, 1996, Vol.88 (1), p.78-78

1996

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POTENTIATION OF THE APOPTOTIC EFFECT OF CHLOROETHYLNITROSOUREAS BY A NEW O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE INHIBITOR

Biology of the cell, 1996, Vol.88 (1-2), p.78-78

1996

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Effects of cyclosporine A on Ia antigen expression in N-nitroso-N-methylurea-induced rat mammary tumors

Cancer research (Chicago, Ill.), 1990-06, Vol.50 (11), p.3301-3305

1990

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Synthesis of all-trans-beta-carotene retinoids and derivatives labelled with 14C

Journal of labelled compounds & radiopharmaceuticals, 1996-05, Vol.38 (5), p.441-451

1996

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Differential effects of n-3 and n-6 polyunsaturated fatty acids on BRCA1 and BRCA2 gene expression in breast cell lines

British journal of nutrition, 2002-04, Vol.87 (4), p.281-289

2002

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Quantification by affinity perfusion chromatography of phosphorylated BRCAl and BRCA2 proteins from tumor cells after lycopene treatment

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005-07, Vol.821 (2), p.188-193

2005

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Synthesis of three no-carrier-added O6-4-[125I] iodobenzylguanosine derivatives, new reagents for the assay of O6-alkylguanine-DNA alkyltransferase activity

Journal of labelled compounds & radiopharmaceuticals, 1995-12, Vol.36 (12), p.1215-1225

1995

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Design, synthesis and preliminary biological evaluations of novel amphiphilic drug carriers

New Quaternary Ammonium Oxicam Derivatives Targeted toward Cartilage: Synthesis, Pharmacokinetic Studies, and Antiinflammatory Potency

Synthesis and in Vitro Evaluation of Quaternary Ammonium Derivatives of Chlorambucil and Melphalan, Anticancer Drugs Designed for the Chemotherapy of Chondrosarcoma

Cytotoxic effects of kinetin riboside on mouse, human and plant tumour cells

Synthesis of N-quaternary ammonium [3H] and [99mTc]polyazamacrocycles, potential radiotracers for cartilage imaging

Synthesis and pharmacokinetic profile of a quaternary ammonium derivative of chlorambucil, a potential anticancer drug for the chemotherapy of chondrosarcoma

Quantification of BRCA1 protein in sporadic breast carcinoma with or without loss of heterozygosity of the BRCA1 gene

Synthesis and in Vivo Biodisposition of [14C]-Quaternary Ammonium−Melphalan Conjugate, a Potential Cartilage-Targeted Alkylating Drug

Presence of BRCA1 and BRCA2 proteins in human milk fat globules after delivery

Synthesis and surface-active properties of glycosyl carbamates and thioureas

Synthesis of 4-tert-butyl-3-(2-chloro -[-2-14C]ethyl)ureido benzene

Cross‐reaction between antibodies raised against the last 20 C‐terminal amino acids of BRCA 1 (C‐20) and human EGF and EGF‐R in MCF 10a human mammary epithelial cell line

Disposition and metabolism of a novel antineoplastic agent, 4-tert-butyl-[3-(2-chloroethyl)ureido]benzene, in mice

Synthesis of new cotelomers derived from tris(hydroxymethyl) aminomethane bearing arabinofuranosylcytosine moieties. Preliminary results on their in vitro and in vivo antitumoral activities

O6-(Alkyl/aralkyl)guanosine and 2‘-Deoxyguanosine Derivatives: Synthesis and Ability To Enhance Chloroethylnitrosourea Antitumor Action

Synthesis of carbon-14 labelled (3-{[(Z)-5-chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-1H-indol-1-yle]carbonylamino}propyl)trimethylammonium chloride, a potential cartilage-targeted antirheumatic drug

Determination of BRCA2 oncosuppressor protein expression in human mammary cells by affinity perfusion high-performance chromatography

Application to a cartilage targeting strategy: synthesis and in vivo biodistribution of (14)C-labeled quaternary ammonium-glucosamine conjugates

Potentiation of the apoptotic effect of chloroethylnitrosoureas by a new O 6-alkylguanine-DNA alkyltransferase inhibitor

POTENTIATION OF THE APOPTOTIC EFFECT OF CHLOROETHYLNITROSOUREAS BY A NEW O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE INHIBITOR

Effects of cyclosporine A on Ia antigen expression in N-nitroso-N-methylurea-induced rat mammary tumors

Synthesis of all-trans-beta-carotene retinoids and derivatives labelled with 14C

Differential effects of n-3 and n-6 polyunsaturated fatty acids on BRCA1 and BRCA2 gene expression in breast cell lines

Quantification by affinity perfusion chromatography of phosphorylated BRCAl and BRCA2 proteins from tumor cells after lycopene treatment

Synthesis of three no-carrier-added O6-4-[125I] iodobenzylguanosine derivatives, new reagents for the assay of O6-alkylguanine-DNA alkyltransferase activity

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