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Channeling a complex question

Nature chemical biology, 2020-09, Vol.16 (9), p.935-937

St Maurice, Martin

2020

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Synthesis and Evaluation of 5-(Heteroarylmethylene)hydantoins as Glycogen Synthase Kinase-3β Inhibitors

Pharmaceuticals (Basel, Switzerland), 2024-05, Vol.17 (5), p.570

2024

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Solving the Conundrum: Widespread Proteins Annotated for Urea Metabolism in Bacteria Are Carboxyguanidine Deiminases Mediating Nitrogen Assimilation from Guanidine

Biochemistry (Easton), 2020-09, Vol.59 (35), p.3258-3270

2020

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Conformational Selection Governs Carrier Domain Positioning in Staphylococcus aureus Pyruvate Carboxylase

Biochemistry (Easton), 2022-09, Vol.61 (17), p.1824-1835

2022

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Potent Inhibition of Mandelate Racemase by Boronic Acids: Boron as a Mimic of a Carbon Acid Center

Biochemistry (Easton), 2020-08, Vol.59 (33), p.3026-3037

2020

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Allosteric regulation alters carrier domain translocation in pyruvate carboxylase

Nature communications, 2018-04, Vol.9 (1), p.1384-13, Article 1384

2018

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A high-throughput screening assay for pyruvate carboxylase

Analytical biochemistry, 2018-06, Vol.550, p.90-98

2018

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Domain Architecture of Pyruvate Carboxylase, a Biotin-Dependent Multifunctional Enzyme

Science (American Association for the Advancement of Science), 2007-08, Vol.317 (5841), p.1076-1079

2007

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Examination of the Catalytic Role of the Axial Cystine Ligand in the Co-Type Nitrile Hydratase from Pseudonocardia thermophila JCM 3095

Catalysts, 2021-11, Vol.11 (11), p.1381

2021

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A flagellar A-kinase anchoring protein with two amphipathic helices forms a structural scaffold in the radial spoke complex

The Journal of cell biology, 2012-11, Vol.199 (4), p.639-651

2012

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Writing Assignments with a Metacognitive Component Enhance Learning in a Large Introductory Biology Course

CBE life sciences education, 2014-06, Vol.13 (2), p.311-321

2014

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Flavodoxin:Quinone Reductase (FqrB): a Redox Partner of Pyruvate:Ferredoxin Oxidoreductase That Reversibly Couples Pyruvate Oxidation to NADPH Production in Helicobacter pylori and Campylobacter jejuni

Journal of Bacteriology, 2007-07, Vol.189 (13), p.4764-4773

2007

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Structure of Mandelate Racemase with Bound Intermediate Analogues Benzohydroxamate and Cupferron

Biochemistry (Easton), 2012-02, Vol.51 (6), p.1160-1170

2012

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Interaction between the Biotin Carboxyl Carrier Domain and the Biotin Carboxylase Domain in Pyruvate Carboxylase from Rhizobium etli

Biochemistry (Easton), 2011-11, Vol.50 (45), p.9708-9723

2011

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Residue Phe112 of the Human-Type Corrinoid Adenosyltransferase (PduO) Enzyme of Lactobacillus reuteri Is Critical to the Formation of the Four-Coordinate Co(II) Corrinoid Substrate and to the Activity of the Enzyme

Biochemistry (Easton), 2009-04, Vol.48 (14), p.3138-3145

2009

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Novel Insights into the Biotin Carboxylase Domain Reactions of Pyruvate Carboxylase from Rhizobium etli

Biochemistry (Easton), 2011-11, Vol.50 (45), p.9724-9737

2011

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Structural Characterization of the Active Site of the PduO-Type ATP:Co(I)rrinoid Adenosyltransferase from Lactobacillus reuteri

The Journal of biological chemistry, 2007-01, Vol.282 (4), p.2596-2605

2007

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Structural Characterization of a Human-Type Corrinoid Adenosyltransferase Confirms That Coenzyme B12 Is Synthesized through a Four-Coordinate Intermediate

Biochemistry (Easton), 2008-05, Vol.47 (21), p.5755-5766

2008

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Insight into the Carboxyl Transferase Domain Mechanism of Pyruvate Carboxylase from Rhizobium etli

Biochemistry (Easton), 2009-05, Vol.48 (20), p.4305-4313

2009

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Activation and Inhibition of Pyruvate Carboxylase from Rhizobium etli

Biochemistry (Easton), 2011-11, Vol.50 (45), p.9694-9707

2011

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The enzymes of biotin dependent CO2 metabolism: What structures reveal about their reaction mechanisms

Protein science, 2012-11, Vol.21 (11), p.1597-1619

2012

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The Structure of Allophanate Hydrolase from Granulibacter bethesdensis Provides Insights into Substrate Specificity in the Amidase Signature Family

Biochemistry (Easton), 2013-01, Vol.52 (4), p.690-700

2013

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Synthesis and Evaluation of 1,3-Disubstituted Imidazolidine-2,4,5-triones as Inhibitors of Pyruvate Carboxylase

ACS medicinal chemistry letters, 2024-07, Vol.15 (7), p.1088-1093

2024

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Probing the Catalytic Roles of Arg548 and Gln552 in the Carboxyl Transferase Domain of the Rhizobium etli Pyruvate Carboxylase by Site-Directed Mutagenesis

Biochemistry (Easton), 2010-04, Vol.49 (15), p.3296-3304

2010

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The urea carboxylase and allophanate hydrolase activities of urea amidolyase are functionally independent

Protein science, 2016-10, Vol.25 (10), p.1812-1824

2016

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Channeling a complex question

Synthesis and Evaluation of 5-(Heteroarylmethylene)hydantoins as Glycogen Synthase Kinase-3β Inhibitors

Solving the Conundrum: Widespread Proteins Annotated for Urea Metabolism in Bacteria Are Carboxyguanidine Deiminases Mediating Nitrogen Assimilation from Guanidine

Conformational Selection Governs Carrier Domain Positioning in Staphylococcus aureus Pyruvate Carboxylase

Potent Inhibition of Mandelate Racemase by Boronic Acids: Boron as a Mimic of a Carbon Acid Center

Allosteric regulation alters carrier domain translocation in pyruvate carboxylase

A high-throughput screening assay for pyruvate carboxylase

Domain Architecture of Pyruvate Carboxylase, a Biotin-Dependent Multifunctional Enzyme

Examination of the Catalytic Role of the Axial Cystine Ligand in the Co-Type Nitrile Hydratase from Pseudonocardia thermophila JCM 3095

A flagellar A-kinase anchoring protein with two amphipathic helices forms a structural scaffold in the radial spoke complex

Writing Assignments with a Metacognitive Component Enhance Learning in a Large Introductory Biology Course

Flavodoxin:Quinone Reductase (FqrB): a Redox Partner of Pyruvate:Ferredoxin Oxidoreductase That Reversibly Couples Pyruvate Oxidation to NADPH Production in Helicobacter pylori and Campylobacter jejuni

Structure of Mandelate Racemase with Bound Intermediate Analogues Benzohydroxamate and Cupferron

Interaction between the Biotin Carboxyl Carrier Domain and the Biotin Carboxylase Domain in Pyruvate Carboxylase from Rhizobium etli

Residue Phe112 of the Human-Type Corrinoid Adenosyltransferase (PduO) Enzyme of Lactobacillus reuteri Is Critical to the Formation of the Four-Coordinate Co(II) Corrinoid Substrate and to the Activity of the Enzyme

Novel Insights into the Biotin Carboxylase Domain Reactions of Pyruvate Carboxylase from Rhizobium etli

Structural Characterization of the Active Site of the PduO-Type ATP:Co(I)rrinoid Adenosyltransferase from Lactobacillus reuteri

Structural Characterization of a Human-Type Corrinoid Adenosyltransferase Confirms That Coenzyme B12 Is Synthesized through a Four-Coordinate Intermediate

Insight into the Carboxyl Transferase Domain Mechanism of Pyruvate Carboxylase from Rhizobium etli

Activation and Inhibition of Pyruvate Carboxylase from Rhizobium etli

The enzymes of biotin dependent CO2 metabolism: What structures reveal about their reaction mechanisms

The Structure of Allophanate Hydrolase from Granulibacter bethesdensis Provides Insights into Substrate Specificity in the Amidase Signature Family

Synthesis and Evaluation of 1,3-Disubstituted Imidazolidine-2,4,5-triones as Inhibitors of Pyruvate Carboxylase

Probing the Catalytic Roles of Arg548 and Gln552 in the Carboxyl Transferase Domain of the Rhizobium etli Pyruvate Carboxylase by Site-Directed Mutagenesis

The urea carboxylase and allophanate hydrolase activities of urea amidolyase are functionally independent

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