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Preclinical and clinical development of dexketoprofen

Drugs (New York, N.Y.), 1996, Vol.52 Suppl 5 (Supplement 5), p.24-46

1996

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Stereoselective Inhibition of Inducible Cyclooxygenase by Chiral Nonsteroidal Antiinflammatory Drugs

Journal of clinical pharmacology, 1996-06, Vol.36 (6), p.505-512

1996

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Modeling Cyclooxygenase Inhibition. Implication of Active Site Hydration on the Selectivity of Ketoprofen Analogues

Journal of medicinal chemistry, 2000-06, Vol.43 (11), p.2280-2284

2000

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Clinical comparison of dexketoprofen trometamol, ketoprofen, and placebo in postoperative dental pain

Journal of clinical pharmacology, 1998-12, Vol.38 (S1), p.46S

1998

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PHOTOCHEMICAL AND PHOTOBIOLOGICAL PROPERTIES OF KETOPROFEN ASSOCIATED WITH THE BENZOPHENONE CHROMOPHORE

Photochemistry and photobiology, 1994-08, Vol.60 (2), p.96-101

1994

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Analgesic, Antiinflammatory, and Antipyretic Effects of S(+)‐Ketoprofen In Vivo

Journal of clinical pharmacology, 1998-12, Vol.38 (S1), p.3S-10S

1998

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Comparison of the Efficacy and Tolerability of Dexketoprofen and Ketoprofen in the Treatment of Primary Dysmenorrhea

Journal of clinical pharmacology, 1998-12, Vol.38 (S1), p.65S-73S

1998

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Identification of Novel Cyclooxygenase-2 Selective Inhibitors Using Pharmacophore Models

Journal of medicinal chemistry, 2002-03, Vol.45 (7), p.1402-1411

2002

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Intestinal toxicity of ketoprofen-trometamol vs its enantiomers in rat. Role of oxidative stress

Inflammation research, 2000-11, Vol.49 (11), p.627-632

2000

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Clinical Comparison of Dexketoprofen Trometamol and Dipyrone in Postoperative Dental Pain

Journal of clinical pharmacology, 1998-12, Vol.38 (S1), p.55S-64S

1998

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Pharmacokinetics of Dexketoprofen Trometamol in Healthy Volunteers After Single and Repeated Oral Doses

Journal of clinical pharmacology, 1998-12, Vol.38 (S1), p.33S-40S

1998

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Comparison of Dexketoprofen Trometamol and Ketoprofen in the Treatment of Osteoarthritis of the Knee

Journal of clinical pharmacology, 1998-12, Vol.38 (S1), p.74S-80S

1998

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Comparative molecular modeling study of the three-dimensional structures of prostaglandin endoperoxide H2 synthase 1 and 2 (COX-1 and COX-2)

Journal of molecular graphics & modelling, 1997-10, Vol.15 (5), p.290-300

1997

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Estimation of acute flurbiprofen and ketoprofen toxicity in rat gastric mucosa at therapy-relevant doses

Inflammation research, 2001-12, Vol.50 (12), p.602-608

2001

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Intestinal Ulcerogenic Effect of S(+)‐Ketoprofen in the Rat

Journal of clinical pharmacology, 1998-12, Vol.38 (S1), p.27S-32S

1998

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Stereochemical assignment of erythro and threo isomers of 2-aryloxy-1-(2-piperidyl)ethanol by phase sensitive homocorrelation nuclear magnetic resonance experiments

Canadian journal of chemistry, 1988-11, Vol.66 (11), p.2782-2786

1988

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Rational modification of human synovial fluid phospholipase A2 inhibitors

Journal of medicinal chemistry, 1994-02, Vol.37 (3), p.337-341

1994

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Acid-Promoted Phosphonyl Migration in N-Phosphonyl-α-Aminoalcohols. from N-(2-Hydroxyethyl)Phosphonamides to O-(2-Aminoethyl)Phosphonates

Synthetic communications, 1992-08, Vol.22 (16), p.2373-2380

1992

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Bioavailability of S(+)‐Ketoprofen After Oral Administration of Different Mixtures of Ketoprofen Enantiomers to Dogs

Journal of clinical pharmacology, 1998-12, Vol.38 (S1), p.22S-26S

1998

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Evaluation of ketoprofen (R, S and [formula omitted]) phototoxicity by a battery of in vitro assays

Journal of photochemistry and photobiology. B, Biology, 1995-12, Vol.31 (3), p.133-138

1995

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Synthesis and pharmacological evaluation of new cysLT1 receptor antagonists

European journal of medicinal chemistry, 1997-07, Vol.32 (7-8), p.547-570

1997

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Pruritic Rash in a Pregnant Woman

American family physician, 2013-05, Vol.87 (10), p.723-724

2013

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Antagonistes β-adrénergiques: N-alkyl et N-amidoéthyl (arylalkoxy)propanolamines apparentés au propranolol

European journal of medicinal chemistry, 1988-10, Vol.23 (5), p.421-426

Mauleón, D

1988

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Differential effect of alkyl chain-modified ether lipids on protein kinase C autophosphorylation and histone phosphorylation

Biochemical pharmacology, 1996-12, Vol.52 (12), p.1843-1847

1996

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Derivation of pharmacophore and CoMFA models for leukotriene D(4) receptor antagonists of the quinolinyl(bridged)aryl series

Journal of medicinal chemistry, 2000-02, Vol.43 (3), p.392-400

2000

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Preclinical and clinical development of dexketoprofen

Stereoselective Inhibition of Inducible Cyclooxygenase by Chiral Nonsteroidal Antiinflammatory Drugs

Modeling Cyclooxygenase Inhibition. Implication of Active Site Hydration on the Selectivity of Ketoprofen Analogues

Clinical comparison of dexketoprofen trometamol, ketoprofen, and placebo in postoperative dental pain

PHOTOCHEMICAL AND PHOTOBIOLOGICAL PROPERTIES OF KETOPROFEN ASSOCIATED WITH THE BENZOPHENONE CHROMOPHORE

Analgesic, Antiinflammatory, and Antipyretic Effects of S(+)‐Ketoprofen In Vivo

Comparison of the Efficacy and Tolerability of Dexketoprofen and Ketoprofen in the Treatment of Primary Dysmenorrhea

Identification of Novel Cyclooxygenase-2 Selective Inhibitors Using Pharmacophore Models

Intestinal toxicity of ketoprofen-trometamol vs its enantiomers in rat. Role of oxidative stress

Clinical Comparison of Dexketoprofen Trometamol and Dipyrone in Postoperative Dental Pain

Pharmacokinetics of Dexketoprofen Trometamol in Healthy Volunteers After Single and Repeated Oral Doses

Comparison of Dexketoprofen Trometamol and Ketoprofen in the Treatment of Osteoarthritis of the Knee

Comparative molecular modeling study of the three-dimensional structures of prostaglandin endoperoxide H2 synthase 1 and 2 (COX-1 and COX-2)

Estimation of acute flurbiprofen and ketoprofen toxicity in rat gastric mucosa at therapy-relevant doses

Intestinal Ulcerogenic Effect of S(+)‐Ketoprofen in the Rat

Stereochemical assignment of erythro and threo isomers of 2-aryloxy-1-(2-piperidyl)ethanol by phase sensitive homocorrelation nuclear magnetic resonance experiments

Rational modification of human synovial fluid phospholipase A2 inhibitors

Acid-Promoted Phosphonyl Migration in N-Phosphonyl-α-Aminoalcohols. from N-(2-Hydroxyethyl)Phosphonamides to O-(2-Aminoethyl)Phosphonates

Bioavailability of S(+)‐Ketoprofen After Oral Administration of Different Mixtures of Ketoprofen Enantiomers to Dogs

Evaluation of ketoprofen (R, S and [formula omitted]) phototoxicity by a battery of in vitro assays

Synthesis and pharmacological evaluation of new cysLT1 receptor antagonists

Pruritic Rash in a Pregnant Woman

Antagonistes β-adrénergiques: N-alkyl et N-amidoéthyl (arylalkoxy)propanolamines apparentés au propranolol

Differential effect of alkyl chain-modified ether lipids on protein kinase C autophosphorylation and histone phosphorylation

Derivation of pharmacophore and CoMFA models for leukotriene D(4) receptor antagonists of the quinolinyl(bridged)aryl series

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