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Identification of a tumor-promoter cholesterol metabolite in human breast cancers acting through the glucocorticoid receptor

Proceedings of the National Academy of Sciences - PNAS, 2017-10, Vol.114 (44), p.E9346-E9355

2017

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Dendrogenin A drives LXR to trigger lethal autophagy in cancers

Nature communications, 2017-12, Vol.8 (1), p.1903-17, Article 1903

2017

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Transcriptional regulation of Acsl1 by CHREBP and NF-kappa B in macrophages during hyperglycemia and inflammation

PloS one, 2022-09, Vol.17 (9), p.e0272986-e0272986

2022

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Inhibiting LXRα phosphorylation in hematopoietic cells reduces inflammation and attenuates atherosclerosis and obesity in mice

Communications biology, 2021-03, Vol.4 (1), p.420-420, Article 420

2021

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Neutrophil extracellular traps promote macrophage inflammation and impair atherosclerosis resolution in diabetic mice

JCI insight, 2020-04, Vol.5 (7)

2020

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One step synthesis of 6-oxo-cholestan-3β,5α-diol

Biochemical and biophysical research communications, 2014-04, Vol.446 (3), p.782-785

2014

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LXR[alpha] Phosphorylation in Cardiometabolic Disease: Insight From Mouse Models

Endocrinology (Philadelphia), 2020-07, Vol.161 (7), p.1

2020

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LXRα Phosphorylation in Cardiometabolic Disease: Insight From Mouse Models

Endocrinology (Philadelphia), 2020-07, Vol.161 (7)

2020

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UXT in Sertoli cells is required for blood–testis barrier integrity

Biology of reproduction, 2020-10, Vol.103 (4), p.880-891

2020

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Abstract 2577: ITI-214, a potent and selective PDE1 inhibitor, inhibits tumor growth when combined with a checkpoint inhibitor in a mouse model of breast cancer

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.2577-2577

2022

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Circulating oxysterol metabolites as potential new surrogate markers in patients with hormone receptor-positive breast cancer: Results of the OXYTAM study

The Journal of steroid biochemistry and molecular biology, 2017-05, Vol.169, p.210-218

2017

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Dendrogenin A arises from cholesterol and histamine metabolism and shows cell differentiation and anti-tumour properties

Nature communications, 2013, Vol.4 (1), p.1840, Article 1840

2013

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Abstract 487: ITI-1020, a novel PDE type 1 inhibitor, reduces tumor growth in triple negative breast cancer (TNBC) mouse models

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.487-487

2023

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Impaired LXRα Phosphorylation Attenuates Progression of Fatty Liver Disease

Cell reports (Cambridge), 2019-01, Vol.26 (4), p.984-995.e6

2019

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Synthesis, Optical Properties, and Electronic Structures of Nucleobase-Containing π‑Conjugated Oligomers

Journal of organic chemistry, 2015-02, Vol.80 (3), p.1828-1840

2015

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Abstract P3-05-12: Circulating oxysterol metabolites as potential new surrogate markers for hormonotherapy in patients with hormone receptor-positive breast cancer? A pilot study

Cancer research (Chicago, Ill.), 2015-05, Vol.75 (9_Supplement), p.P3-P3-05-12

2015

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Abstract 1165: Identification of a cholesterol onco-metabolite, promoter of tumor in breast cancers, and of the enzyme involved in its biosynthesis

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.1165-1165

2015

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Abstract 1884: 6-oxo-cholestan-3β,5α-diol (OCDO) is a metabolite produced in tumors by cholesterol epoxide hydrolase activity and a tumor promoter: OCDO inhibition contributes to the anti-tumor activity of tamoxifen and dendrogenin A

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.1884-1884

2013

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2290: Control of atherosclerosis regression by LXRα S198 phosphorylation

Journal of clinical and translational science, 2018-05, Vol.1 (S1), p.5-5

2018

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2290

Journal of clinical and translational science, 2017-09, Vol.1, p.5-5

2017

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2290: Control of atherosclerosis regression by LXR[...]S198 phosphorylation

Journal of clinical and translational science, 2017-09, Vol.1, p.5

2017

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Few-Electron Edge-State Quantum Dots in a Silicon Nanowire Field-Effect Transistor

Nano letters, 2014-04, Vol.14 (4), p.2094-2098

2014

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The NF-κB RelA transcription factor is not required for CD8+ T-cell function in acute viral infection and cancer

Frontiers in immunology, 2024-03, Vol.15, p.1379777-1379777

2024

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IFN-γ Primed Wharton's Jelly Mesenchymal Stromal Cells Inhibit T Cell Proliferation By Synergistic IDO and Mitochondrial Transfer Mechanisms

Blood, 2022-11, Vol.140 (Supplement 1), p.4504-4505

2022

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Identification of a tumor-promoter cholesterol metabolite in human breast cancers acting through the glucocorticoid receptor

Dendrogenin A drives LXR to trigger lethal autophagy in cancers

Transcriptional regulation of Acsl1 by CHREBP and NF-kappa B in macrophages during hyperglycemia and inflammation

Inhibiting LXRα phosphorylation in hematopoietic cells reduces inflammation and attenuates atherosclerosis and obesity in mice

Neutrophil extracellular traps promote macrophage inflammation and impair atherosclerosis resolution in diabetic mice

One step synthesis of 6-oxo-cholestan-3β,5α-diol

LXR[alpha] Phosphorylation in Cardiometabolic Disease: Insight From Mouse Models

LXRα Phosphorylation in Cardiometabolic Disease: Insight From Mouse Models

UXT in Sertoli cells is required for blood–testis barrier integrity

Abstract 2577: ITI-214, a potent and selective PDE1 inhibitor, inhibits tumor growth when combined with a checkpoint inhibitor in a mouse model of breast cancer

Circulating oxysterol metabolites as potential new surrogate markers in patients with hormone receptor-positive breast cancer: Results of the OXYTAM study

Dendrogenin A arises from cholesterol and histamine metabolism and shows cell differentiation and anti-tumour properties

Abstract 487: ITI-1020, a novel PDE type 1 inhibitor, reduces tumor growth in triple negative breast cancer (TNBC) mouse models

Impaired LXRα Phosphorylation Attenuates Progression of Fatty Liver Disease

Synthesis, Optical Properties, and Electronic Structures of Nucleobase-Containing π‑Conjugated Oligomers

Abstract P3-05-12: Circulating oxysterol metabolites as potential new surrogate markers for hormonotherapy in patients with hormone receptor-positive breast cancer? A pilot study

Abstract 1165: Identification of a cholesterol onco-metabolite, promoter of tumor in breast cancers, and of the enzyme involved in its biosynthesis

Abstract 1884: 6-oxo-cholestan-3β,5α-diol (OCDO) is a metabolite produced in tumors by cholesterol epoxide hydrolase activity and a tumor promoter: OCDO inhibition contributes to the anti-tumor activity of tamoxifen and dendrogenin A

2290: Control of atherosclerosis regression by LXRα S198 phosphorylation

2290

2290: Control of atherosclerosis regression by LXR[...]S198 phosphorylation

Few-Electron Edge-State Quantum Dots in a Silicon Nanowire Field-Effect Transistor

Worsening and newly diagnosed paraneoplastic syndromes following anti-PD-1 or anti-PD-L1 immunotherapies, a descriptive study

The NF-κB RelA transcription factor is not required for CD8+ T-cell function in acute viral infection and cancer

IFN-γ Primed Wharton's Jelly Mesenchymal Stromal Cells Inhibit T Cell Proliferation By Synergistic IDO and Mitochondrial Transfer Mechanisms

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