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Adrenomedullin and Adrenomedullin-Targeted Therapy As Treatment Strategies Relevant for Sepsis

Frontiers in immunology, 2018-02, Vol.9, p.292-292

2018

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Letter to the Editor: Vitamin D deficiency in COVID-19: Mixing up cause and consequence

Metabolism, clinical and experimental, 2021-02, Vol.115, p.154434-154434, Article 154434

2021

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Noradrenaline drives immunosuppression in sepsis: clinical consequences

Intensive care medicine, 2020-06, Vol.46 (6), p.1246-1248

2020

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Immunotherapy for the Adjunctive Treatment of Sepsis: From Immunosuppression to Immunostimulation: Time for a Paradigm Change?

American journal of respiratory and critical care medicine, 2013-06, Vol.187 (12), p.1287-1293

2013

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Precision Immunotherapy for Sepsis

Frontiers in immunology, 2018-09, Vol.9, p.1926-1926

2018

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Monocytic HLA-DR expression kinetics in septic shock patients with different pathogens, sites of infection and adverse outcomes

Critical care (London, England), 2020-03, Vol.24 (1), p.110-110, Article 110

2020

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Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis

Nature immunology, 2016-04, Vol.17 (4), p.406-413

2016

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CytoSorb hemoperfusion markedly attenuates circulating cytokine concentrations during systemic inflammation in humans in vivo

Critical care (London, England), 2023-03, Vol.27 (1), p.117-11, Article 117

2023

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Body Mass Index and Mortality in Coronavirus Disease 2019 and Other Diseases: A Cohort Study in 35,506 ICU Patients

Critical care medicine, 2022-01, Vol.50 (1), p.e1-e10

2022

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Dexamethasone and tocilizumab treatment considerably reduces the value of C-reactive protein and procalcitonin to detect secondary bacterial infections in COVID-19 patients

Critical care (London, England), 2021-08, Vol.25 (1), p.1-281, Article 281

2021

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Voluntary activation of the sympathetic nervous system and attenuation of the innate immune response in humans

Proceedings of the National Academy of Sciences - PNAS, 2014-05, Vol.111 (20), p.7379-7384

2014

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IFN-γ-stimulated neutrophils suppress lymphocyte proliferation through expression of PD-L1

PloS one, 2013-08, Vol.8 (8), p.e72249-e72249

2013

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Spleen‐derived IFN‐γ induces generation of PD‐L1+‐suppressive neutrophils during endotoxemia

Journal of leukocyte biology, 2017-12, Vol.102 (6), p.1401-1409

2017

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Effects of the Humanized Anti-Adrenomedullin Antibody Adrecizumab (HAM8101) on Vascular Barrier Function and Survival in Rodent Models of Systemic Inflammation and Sepsis

Shock (Augusta, Ga.), 2018-12, Vol.50 (6), p.648-654

2018

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Enteroendocrine L Cells Sense LPS after Gut Barrier Injury to Enhance GLP-1 Secretion

Cell reports (Cambridge), 2017-10, Vol.21 (5), p.1160-1168

2017

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Increased Plasma Heparanase Activity in COVID-19 Patients

Frontiers in immunology, 2020-10, Vol.11, p.575047-575047

2020

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Safety, tolerability and pharmacokinetics/pharmacodynamics of the adrenomedullin antibody adrecizumab in a first‐in‐human study and during experimental human endotoxaemia in healthy subjects

British journal of clinical pharmacology, 2018-09, Vol.84 (9), p.2129-2141

2018

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Increased blood angiotensin converting enzyme 2 activity in critically ill COVID-19 patients

ERJ open research, 2021-01, Vol.7 (1), p.848

2021

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The effects of orally administered Beta-glucan on innate immune responses in humans, a randomized open-label intervention pilot-study

PloS one, 2014-09, Vol.9 (9), p.e108794

2014

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Interferon-gamma as adjunctive immunotherapy for invasive fungal infections: a case series

BMC infectious diseases, 2014-03, Vol.14 (1), p.166-166, Article 166

2014

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Biomarkers for antimicrobial stewardship: a reappraisal in COVID-19 times?

Critical care (London, England), 2020-10, Vol.24 (1), p.1-600, Article 600

2020

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Preclinical and first-in-human safety studies on a novel magnetism-based haemofiltration method

Scientific reports, 2024-06, Vol.14 (1), p.14077-15

2024

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Complement activation in severely ill patients with sepsis: no relationship with inflammation and disease severity

Critical care (London, England), 2023-02, Vol.27 (1), p.63-63, Article 63

2023

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The chicken or the egg: low testosterone predisposes for COVID-19 or COVID-19 induces a decrease in testosterone?

Critical care (London, England), 2021-07, Vol.25 (1), p.1-237, Article 237

2021

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Clinical sepsis phenotypes in critically ill COVID-19 patients

Critical care (London, England), 2022-08, Vol.26 (1), p.1-244, Article 244

2022

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Adrenomedullin and Adrenomedullin-Targeted Therapy As Treatment Strategies Relevant for Sepsis

Letter to the Editor: Vitamin D deficiency in COVID-19: Mixing up cause and consequence

Noradrenaline drives immunosuppression in sepsis: clinical consequences

Immunotherapy for the Adjunctive Treatment of Sepsis: From Immunosuppression to Immunostimulation: Time for a Paradigm Change?

Precision Immunotherapy for Sepsis

Monocytic HLA-DR expression kinetics in septic shock patients with different pathogens, sites of infection and adverse outcomes

Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis

CytoSorb hemoperfusion markedly attenuates circulating cytokine concentrations during systemic inflammation in humans in vivo

Body Mass Index and Mortality in Coronavirus Disease 2019 and Other Diseases: A Cohort Study in 35,506 ICU Patients

Dexamethasone and tocilizumab treatment considerably reduces the value of C-reactive protein and procalcitonin to detect secondary bacterial infections in COVID-19 patients

Voluntary activation of the sympathetic nervous system and attenuation of the innate immune response in humans

IFN-γ-stimulated neutrophils suppress lymphocyte proliferation through expression of PD-L1

Spleen‐derived IFN‐γ induces generation of PD‐L1+‐suppressive neutrophils during endotoxemia

Effects of the Humanized Anti-Adrenomedullin Antibody Adrecizumab (HAM8101) on Vascular Barrier Function and Survival in Rodent Models of Systemic Inflammation and Sepsis

Enteroendocrine L Cells Sense LPS after Gut Barrier Injury to Enhance GLP-1 Secretion

Increased Plasma Heparanase Activity in COVID-19 Patients

Safety, tolerability and pharmacokinetics/pharmacodynamics of the adrenomedullin antibody adrecizumab in a first‐in‐human study and during experimental human endotoxaemia in healthy subjects

Increased blood angiotensin converting enzyme 2 activity in critically ill COVID-19 patients

The effects of orally administered Beta-glucan on innate immune responses in humans, a randomized open-label intervention pilot-study

Interferon-gamma as adjunctive immunotherapy for invasive fungal infections: a case series

Biomarkers for antimicrobial stewardship: a reappraisal in COVID-19 times?

Preclinical and first-in-human safety studies on a novel magnetism-based haemofiltration method

Complement activation in severely ill patients with sepsis: no relationship with inflammation and disease severity

The chicken or the egg: low testosterone predisposes for COVID-19 or COVID-19 induces a decrease in testosterone?

Clinical sepsis phenotypes in critically ill COVID-19 patients

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