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Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model

Journal of hepatology, 2010-05, Vol.52 (5), p.727-736

2010

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eNOS deletion impairs mitochondrial quality control and exacerbates Western diet-induced NASH

American journal of physiology: endocrinology and metabolism, 2019-10, Vol.317 (4), p.E605-E616

2019

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Hepatocyte-Specific Hepatocyte Nuclear Factor 4 Alpha (HNF4) Deletion Decreases Resting Energy Expenditure by Disrupting Lipid and Carbohydrate Homeostasis

Gene expression, 2021-06, Vol.20 (3), p.157-168

2021

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PGC-1α overexpression results in increased hepatic fatty acid oxidation with reduced triacylglycerol accumulation and secretion

American journal of physiology: Gastrointestinal and liver physiology, 2012-10, Vol.303 (8), p.G979-G992

2012

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Daily exercise vs. caloric restriction for prevention of nonalcoholic fatty liver disease in the OLETF rat model

American journal of physiology: Gastrointestinal and liver physiology, 2011-05, Vol.300 (5), p.G874-G883

2011

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Impact of Various Exercise Modalities on Hepatic Mitochondrial Function

Medicine and science in sports and exercise, 2014-06, Vol.46 (6), p.1089-1097

2014

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Intrinsic (Genetic) Aerobic Fitness Impacts Susceptibility for Metabolic Disease

Exercise and sport sciences reviews, 2017-01, Vol.45 (1), p.7-15

2017

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Heat shock protein 72 regulates hepatic lipid accumulation

American journal of physiology. Regulatory, integrative and comparative physiology, 2018-10, Vol.315 (4), p.R696-R707

2018

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The role of angiotensin II in nonalcoholic steatohepatitis

Molecular and cellular endocrinology, 2013-09, Vol.378 (1-2), p.29-40

2013

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Combining metformin and aerobic exercise training in the treatment of type 2 diabetes and NAFLD in OLETF rats

American journal of physiology: endocrinology and metabolism, 2014-02, Vol.306 (3), p.E300-E310

2014

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Increased aerobic capacity reduces susceptibility to acute high‐fat diet‐induced weight gain

Obesity (Silver Spring, Md.), 2016-09, Vol.24 (9), p.1929-1937

2016

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Angiotensin II-induced NADPH Oxidase Activation Impairs Insulin Signaling in Skeletal Muscle Cells

The Journal of biological chemistry, 2006-11, Vol.281 (46), p.35137-35146

2006

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High-Fat Diet Alters Serum Fatty Acid Profiles in Obesity Prone Rats: Implications for In Vitro Studies

Lipids, 2015-10, Vol.50 (10), p.997-1008

2015

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Mitochondria-lysosome-related organelles mediate mitochondrial clearance during cellular dedifferentiation

Cell reports (Cambridge), 2023-10, Vol.42 (10), p.113291-113291, Article 113291

2023

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Reduced Liver-Specific PGC1a Increases Susceptibility for Short-Term Diet-Induced Weight Gain in Male Mice

Nutrients, 2021-07, Vol.13 (8), p.2596

2021

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Intrinsic aerobic capacity impacts susceptibility to acute high-fat diet-induced hepatic steatosis

American journal of physiology: endocrinology and metabolism, 2014-08, Vol.307 (4), p.E355-E364

2014

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Aerobic exercise training in the treatment of non‐alcoholic fatty liver disease related fibrosis

The Journal of physiology, 2016-09, Vol.594 (18), p.5271-5284

2016

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Female rats selectively bred for high intrinsic aerobic fitness are protected from ovariectomy-associated metabolic dysfunction

American journal of physiology. Regulatory, integrative and comparative physiology, 2015-03, Vol.308 (6), p.R530-R542

2015

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Rats selectively bred for low aerobic capacity have reduced hepatic mitochondrial oxidative capacity and susceptibility to hepatic steatosis and injury

The Journal of physiology, 2009-04, Vol.587 (8), p.1805-1816

2009

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The presence of the ovary prevents hepatic mitochondrial oxidative stress in young and aged female mice through glutathione peroxidase 1

Experimental gerontology, 2016-01, Vol.73, p.14-22

2016

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VCD-induced menopause mouse model reveals reprogramming of hepatic metabolism

Molecular metabolism (Germany), 2024-04, Vol.82, p.101908-101908, Article 101908

2024

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Fibroblast growth factor 21 and exercise-induced hepatic mitochondrial adaptations

American journal of physiology: Gastrointestinal and liver physiology, 2016-05, Vol.310 (10), p.G832-G843

2016

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Angiotensin II-induced non-alcoholic fatty liver disease is mediated by oxidative stress in transgenic TG(mRen2)27(Ren2) rats

Journal of hepatology, 2008-09, Vol.49 (3), p.417-428

2008

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Voluntary Wheel Running Selectively Augments Insulin-Stimulated Vasodilation in Arterioles from White Skeletal Muscle of Insulin-Resistant Rats

Microcirculation (New York, N.Y. 1994), 2012-11, Vol.19 (8), p.729-738

2012

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Rats with high aerobic capacity display enhanced transcriptional adaptability and upregulation of bile acid metabolism in response to an acute high‐fat diet

Physiological reports, 2022-08, Vol.10 (15), p.e15405-n/a

2022

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Mitochondrial dysfunction precedes insulin resistance and hepatic steatosis and contributes to the natural history of non-alcoholic fatty liver disease in an obese rodent model

eNOS deletion impairs mitochondrial quality control and exacerbates Western diet-induced NASH

Hepatocyte-Specific Hepatocyte Nuclear Factor 4 Alpha (HNF4) Deletion Decreases Resting Energy Expenditure by Disrupting Lipid and Carbohydrate Homeostasis

PGC-1α overexpression results in increased hepatic fatty acid oxidation with reduced triacylglycerol accumulation and secretion

Daily exercise vs. caloric restriction for prevention of nonalcoholic fatty liver disease in the OLETF rat model

Impact of Various Exercise Modalities on Hepatic Mitochondrial Function

Intrinsic (Genetic) Aerobic Fitness Impacts Susceptibility for Metabolic Disease

Heat shock protein 72 regulates hepatic lipid accumulation

The role of angiotensin II in nonalcoholic steatohepatitis

Combining metformin and aerobic exercise training in the treatment of type 2 diabetes and NAFLD in OLETF rats

Increased aerobic capacity reduces susceptibility to acute high‐fat diet‐induced weight gain

Angiotensin II-induced NADPH Oxidase Activation Impairs Insulin Signaling in Skeletal Muscle Cells

High-Fat Diet Alters Serum Fatty Acid Profiles in Obesity Prone Rats: Implications for In Vitro Studies

Mitochondria-lysosome-related organelles mediate mitochondrial clearance during cellular dedifferentiation

Reduced Liver-Specific PGC1a Increases Susceptibility for Short-Term Diet-Induced Weight Gain in Male Mice

Intrinsic aerobic capacity impacts susceptibility to acute high-fat diet-induced hepatic steatosis

Aerobic exercise training in the treatment of non‐alcoholic fatty liver disease related fibrosis

Female rats selectively bred for high intrinsic aerobic fitness are protected from ovariectomy-associated metabolic dysfunction

Rats selectively bred for low aerobic capacity have reduced hepatic mitochondrial oxidative capacity and susceptibility to hepatic steatosis and injury

The presence of the ovary prevents hepatic mitochondrial oxidative stress in young and aged female mice through glutathione peroxidase 1

VCD-induced menopause mouse model reveals reprogramming of hepatic metabolism

Fibroblast growth factor 21 and exercise-induced hepatic mitochondrial adaptations

Angiotensin II-induced non-alcoholic fatty liver disease is mediated by oxidative stress in transgenic TG(mRen2)27(Ren2) rats

Voluntary Wheel Running Selectively Augments Insulin-Stimulated Vasodilation in Arterioles from White Skeletal Muscle of Insulin-Resistant Rats

Rats with high aerobic capacity display enhanced transcriptional adaptability and upregulation of bile acid metabolism in response to an acute high‐fat diet

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