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Ubiquitin-based anticancer therapy: Carpet bombing with proteasome inhibitors vs surgical strikes with E1, E2, E3, or DUB inhibitors

Biochimica et biophysica acta, 2012-11, Vol.1823 (11), p.2014-2021

2012

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SUMO fusion technology for difficult-to-express proteins

Protein expression and purification, 2005-09, Vol.43 (1), p.1-9

2005

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Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60

PloS one, 2017-12, Vol.12 (12), p.e0189744-e0189744

2017

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Selective Dual Inhibitors of the Cancer-Related Deubiquitylating Proteases USP7 and USP47

ACS medicinal chemistry letters, 2012-10, Vol.3 (10), p.789-792

2012

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SUMO fusions and SUMO-specific protease for efficient expression and purification of proteins

Journal of structural and functional genomics, 2004-03, Vol.5 (1-2), p.75-86

2004

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Characterization of ubiquitin and ubiquitin‐like‐protein isopeptidase activities

Protein science, 2008-06, Vol.17 (6), p.1035-1043

2008

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Strategies for the identification of ubiquitin ligase inhibitors

Biochemical Society transactions, 2010-02, Vol.38 (Pt 1), p.132-136

2010

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Characterization of selective ubiquitin and ubiquitin-like protease inhibitors using a fluorescence-based multiplex assay format

Assay and drug development technologies, 2011-04, Vol.9 (2), p.165-173

2011

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Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

Oncogene, 1999-07, Vol.18 (28), p.4047-4054

1999

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Targeting the Ubiquitin E3 Ligase MuRF1 to Inhibit Muscle Atrophy

Cell biochemistry and biophysics, 2011-06, Vol.60 (1-2), p.113-118

2011

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Deubiquitinating enzymes as novel anticancer targets

Future oncology (London, England), 2007-04, Vol.3 (2), p.191-199

2007

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4-Aryl-1,2,3-triazole: A Novel Template for a Reversible Methionine Aminopeptidase 2 Inhibitor, Optimized To Inhibit Angiogenesis in Vivo

Journal of medicinal chemistry, 2005-09, Vol.48 (18), p.5644-5647

2005

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Abstract 559: Small molecule T-reg inhibitors for cancer immunotherapy

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.559-559

2016

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Analysis of ubiquitin E3 ligase activity using selective polyubiquitin binding proteins

Biochimica et biophysica acta, 2012-11, Vol.1823 (11), p.2094-2097

2012

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Strategies for the identification of novel inhibitors of deubiquitinating enzymes

Biochemical Society transactions, 2008-10, Vol.36 (Pt 5), p.828-832

2008

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Comprehensive Ubiquitin E2 Profiling of Ten Ubiquitin E3 Ligases

Cell biochemistry and biophysics, 2013-09, Vol.67 (1), p.161-167

2013

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The identification and characterization of the marine natural product scytonemin as a novel antiproliferative pharmacophore

The Journal of pharmacology and experimental therapeutics, 2002-11, Vol.303 (2), p.858-866

2002

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Expression and purification of SARS coronavirus proteins using SUMO-fusions

Protein expression and purification, 2005-07, Vol.42 (1), p.100-110

2005

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Enhanced expression and purification of membrane proteins by SUMO fusion in Escherichia coli

Journal of structural and functional genomics, 2005-09, Vol.6 (2-3), p.103-111

2005

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Using Ubiquitin Binders to Decipher the Ubiquitin Code

Trends in biochemical sciences (Amsterdam. Regular ed.), 2019-07, Vol.44 (7), p.599-615

2019

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Detection and characterization of SUMO protease activity using a sensitive enzyme-based reporter assay

Methods in molecular biology (Clifton, N.J.), 2009, Vol.497, p.269

2009

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Strukturen, Funktionen und kultur-historische Entwicklung der psychosozialen Beratungsstellen mit dem Angebot gebührenfreier Lebensberatung in Deutschland und in den USA: Eine vergleichende empirische Untersuchung am Beispiel von Bremen und Columbus, Ohio

Mattern, Michael

2011

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Interoceptive Sensitivity Modulates Anxiety During Public Speaking

Journal of psychophysiology, 2009-01, Vol.23 (2), p.85-94

2009

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Chfr regulates a mitotic stress pathway through its RING-finger domain with ubiquitin ligase activity

Cancer research (Chicago, Ill.), 2002-03, Vol.62 (6), p.1797-1801

2002

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Caffeine Abolishes the Mammalian G2/M DNA Damage Checkpoint by Inhibiting Ataxia-Telangiectasia-mutated Kinase Activity

The Journal of biological chemistry, 2000-04, Vol.275 (14), p.10342-10348

2000

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Ubiquitin-based anticancer therapy: Carpet bombing with proteasome inhibitors vs surgical strikes with E1, E2, E3, or DUB inhibitors

SUMO fusion technology for difficult-to-express proteins

Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60

Selective Dual Inhibitors of the Cancer-Related Deubiquitylating Proteases USP7 and USP47

SUMO fusions and SUMO-specific protease for efficient expression and purification of proteins

Characterization of ubiquitin and ubiquitin‐like‐protein isopeptidase activities

Strategies for the identification of ubiquitin ligase inhibitors

Characterization of selective ubiquitin and ubiquitin-like protease inhibitors using a fluorescence-based multiplex assay format

Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

Targeting the Ubiquitin E3 Ligase MuRF1 to Inhibit Muscle Atrophy

Deubiquitinating enzymes as novel anticancer targets

4-Aryl-1,2,3-triazole: A Novel Template for a Reversible Methionine Aminopeptidase 2 Inhibitor, Optimized To Inhibit Angiogenesis in Vivo

Abstract 559: Small molecule T-reg inhibitors for cancer immunotherapy

Analysis of ubiquitin E3 ligase activity using selective polyubiquitin binding proteins

Strategies for the identification of novel inhibitors of deubiquitinating enzymes

Comprehensive Ubiquitin E2 Profiling of Ten Ubiquitin E3 Ligases

The identification and characterization of the marine natural product scytonemin as a novel antiproliferative pharmacophore

Expression and purification of SARS coronavirus proteins using SUMO-fusions

Enhanced expression and purification of membrane proteins by SUMO fusion in Escherichia coli

Using Ubiquitin Binders to Decipher the Ubiquitin Code

Detection and characterization of SUMO protease activity using a sensitive enzyme-based reporter assay

Strukturen, Funktionen und kultur-historische Entwicklung der psychosozialen Beratungsstellen mit dem Angebot gebührenfreier Lebensberatung in Deutschland und in den USA: Eine vergleichende empirische Untersuchung am Beispiel von Bremen und Columbus, Ohio

Interoceptive Sensitivity Modulates Anxiety During Public Speaking

Chfr regulates a mitotic stress pathway through its RING-finger domain with ubiquitin ligase activity

Caffeine Abolishes the Mammalian G2/M DNA Damage Checkpoint by Inhibiting Ataxia-Telangiectasia-mutated Kinase Activity

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