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Hot-Melt Extrusion-Based Dexamethasone-PLGA Implants: Physicochemical, Physicomechanical, and Surface Morphological Properties and In Vitro Release Corrected for Drug Degradation

Pharmaceutics, 2024-07, Vol.16 (7), p.895

2024

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Corneal Permeability and Uptake of Twenty-Five Drugs: Species Comparison and Quantitative Structure-Permeability Relationships

Pharmaceutics, 2023-06, Vol.15 (6), p.1646

2023

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Mapping Structurally Defined Guanine Oxidation Products along DNA Duplexes: Influence of Local Sequence Context and Endogenous Cytosine Methylation

Journal of the American Chemical Society, 2014-03, Vol.136 (11), p.4223-4235

2014

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The role of KCC2 in hyperexcitability of the neonatal brain

Neuroscience letters, 2020-11, Vol.738, p.135324-135324, Article 135324

2020

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The validation of new CHD1L inhibitors as a therapeutic strategy for cancer

Biomedicine & pharmacotherapy, 2024-01, Vol.170, p.116037-116037, Article 116037

2024

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Brain Distribution and Metabolism of Flupirtine, a Nonopioid Analgesic Drug with Antiseizure Effects, in Neonatal Rats

Pharmaceutics, 2018-12, Vol.10 (4), p.281

2018

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Comparative metabolism of furan in rodent and human cryopreserved hepatocytes

Drug metabolism and disposition, 2014-07, Vol.42 (7), p.1132-1136

2014

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Quantitative analysis of the oxidative DNA lesion, 2,2-diamino-4-(2-deoxy-beta-D-erythro-pentofuranosyl)amino]-5(2H)-oxazolone (oxazolone), in vitro and in vivo by isotope dilution-capillary HPLC-ESI-MS/MS

Nucleic acids research, 2006-11, Vol.34 (19), p.5449-5460

2006

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Quantitative Analysis of Trihydroxybutyl Mercapturic Acid, a Urinary Metabolite of 1,3-Butadiene, in Humans

Chemical research in toxicology, 2011-09, Vol.24 (9), p.1516-1526

2011

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Glutathione trapping to measure microsomal oxidation of furan to cis-2-butene-1,4-dial

Drug metabolism and disposition, 2005-10, Vol.33 (10), p.1453-1458

2005

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Electron Withdrawing Substituents on Equatorial and Apical Phosphines Have Opposite Effects on the Regioselectivity of Rhodium Catalyzed Hydroformylation

Journal of the American Chemical Society, 1997-12, Vol.119 (49), p.11817-11825

1997

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Identification of a cis-2-Butene-1,4-dial-derived Glutathione Conjugate in the Urine of Furan-Treated Rats

Chemical research in toxicology, 2006-09, Vol.19 (9), p.1138-1141

2006

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Dexamethasone Degradation in Aqueous Medium and Implications for Correction of In Vitro Release from Sustained Release Delivery Systems

AAPS PharmSciTech, 2019-11, Vol.20 (8), p.320-320, Article 320

2019

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Electronically Dissymmetric DIPHOS Derivatives Give Higher n:i Regioselectivity in Rhodium-Catalyzed Hydroformylation Than Either of Their Symmetric Counterparts

Journal of the American Chemical Society, 1999-01, Vol.121 (1), p.63-70

1999

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Mapping three guanine oxidation products along DNA following exposure to three types of reactive oxygen species

Free radical biology & medicine, 2018-06, Vol.121, p.180-189

2018

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A High-Throughput LC-MS/MS Method for the Simultaneous Quantification of Twenty-Seven Drug Molecules in Ocular Tissues

AAPS PharmSciTech, 2022-07, Vol.23 (6), p.192-192, Article 192

2022

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High throughput HPLC–ESI−-MS/MS methodology for mercapturic acid metabolites of 1,3-butadiene: Biomarkers of exposure and bioactivation

Chemico-biological interactions, 2015-11, Vol.241, p.23-31

2015

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Design, Synthesis, and Biological Evaluation of the First Inhibitors of Oncogenic CHD1L

Journal of medicinal chemistry, 2022-03, Vol.65 (5), p.3943-3961

2022

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A Pharmacodynamic Analysis of Choroidal Neovascularization in a Porcine Model Using Three Targeted Drugs

Investigative ophthalmology & visual science, 2017-07, Vol.58 (9), p.3732-3740

2017

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Quantitative High-Performance Liquid Chromatography−Electrospray Ionization Tandem Mass Spectrometry Analysis of Bis-N7-Guanine DNA−DNA Cross-Links in White Blood Cells of Cancer Patients Receiving Cyclophosphamide Therapy

Analytical chemistry (Washington), 2010-05, Vol.82 (9), p.3650-3658

2010

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Quantitative High-Performance Liquid Chromatography−Electrospray Ionization Tandem Mass Spectrometry Analysis of Bis- N 7-Guanine DNA−DNA Cross-Links in White Blood Cells of Cancer Patients Receiving Cyclophosphamide Therapy

Analytical chemistry (Washington), 2010-05, Vol.82 (9), p.3650-3658

2010

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Epicatechin-rich cocoa polyphenol inhibits Kras-activated pancreatic ductal carcinoma cell growth in vitro and in a mouse model

International journal of cancer, 2012-10, Vol.131 (7), p.1720-1731

2012

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Formation of Benzo[a]pyrene Diol Epoxide−DNA Adducts at Specific Guanines within K-ras and p53 Gene Sequences: Stable Isotope-Labeling Mass Spectrometry Approach

Biochemistry (Easton), 2002-07, Vol.41 (30), p.9535-9544

2002

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Formation of Diastereomeric Benzo[a ]pyrene Diol Epoxide-Guanine Adducts in p53 Gene-Derived DNA Sequences

Chemical research in toxicology, 2004-06, Vol.17 (6), p.731-741

2004

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Sequence Distribution of Acetaldehyde-Derived N 2-Ethyl-dG Adducts along Duplex DNA

Chemical research in toxicology, 2007-10, Vol.20 (10), p.1379-1387

2007

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Hot-Melt Extrusion-Based Dexamethasone-PLGA Implants: Physicochemical, Physicomechanical, and Surface Morphological Properties and In Vitro Release Corrected for Drug Degradation

Corneal Permeability and Uptake of Twenty-Five Drugs: Species Comparison and Quantitative Structure-Permeability Relationships

Mapping Structurally Defined Guanine Oxidation Products along DNA Duplexes: Influence of Local Sequence Context and Endogenous Cytosine Methylation

The role of KCC2 in hyperexcitability of the neonatal brain

The validation of new CHD1L inhibitors as a therapeutic strategy for cancer

Brain Distribution and Metabolism of Flupirtine, a Nonopioid Analgesic Drug with Antiseizure Effects, in Neonatal Rats

Comparative metabolism of furan in rodent and human cryopreserved hepatocytes

Quantitative analysis of the oxidative DNA lesion, 2,2-diamino-4-(2-deoxy-beta-D-erythro-pentofuranosyl)amino]-5(2H)-oxazolone (oxazolone), in vitro and in vivo by isotope dilution-capillary HPLC-ESI-MS/MS

Quantitative Analysis of Trihydroxybutyl Mercapturic Acid, a Urinary Metabolite of 1,3-Butadiene, in Humans

Glutathione trapping to measure microsomal oxidation of furan to cis-2-butene-1,4-dial

Electron Withdrawing Substituents on Equatorial and Apical Phosphines Have Opposite Effects on the Regioselectivity of Rhodium Catalyzed Hydroformylation

Identification of a cis-2-Butene-1,4-dial-derived Glutathione Conjugate in the Urine of Furan-Treated Rats

Dexamethasone Degradation in Aqueous Medium and Implications for Correction of In Vitro Release from Sustained Release Delivery Systems

Electronically Dissymmetric DIPHOS Derivatives Give Higher n:i Regioselectivity in Rhodium-Catalyzed Hydroformylation Than Either of Their Symmetric Counterparts

Mapping three guanine oxidation products along DNA following exposure to three types of reactive oxygen species

A High-Throughput LC-MS/MS Method for the Simultaneous Quantification of Twenty-Seven Drug Molecules in Ocular Tissues

High throughput HPLC–ESI−-MS/MS methodology for mercapturic acid metabolites of 1,3-butadiene: Biomarkers of exposure and bioactivation

Design, Synthesis, and Biological Evaluation of the First Inhibitors of Oncogenic CHD1L

A Pharmacodynamic Analysis of Choroidal Neovascularization in a Porcine Model Using Three Targeted Drugs

Quantitative High-Performance Liquid Chromatography−Electrospray Ionization Tandem Mass Spectrometry Analysis of Bis-N7-Guanine DNA−DNA Cross-Links in White Blood Cells of Cancer Patients Receiving Cyclophosphamide Therapy

Quantitative High-Performance Liquid Chromatography−Electrospray Ionization Tandem Mass Spectrometry Analysis of Bis- N 7-Guanine DNA−DNA Cross-Links in White Blood Cells of Cancer Patients Receiving Cyclophosphamide Therapy

Epicatechin-rich cocoa polyphenol inhibits Kras-activated pancreatic ductal carcinoma cell growth in vitro and in a mouse model

Formation of Benzo[a]pyrene Diol Epoxide−DNA Adducts at Specific Guanines within K-ras and p53 Gene Sequences: Stable Isotope-Labeling Mass Spectrometry Approach

Formation of Diastereomeric Benzo[a ]pyrene Diol Epoxide-Guanine Adducts in p53 Gene-Derived DNA Sequences

Sequence Distribution of Acetaldehyde-Derived N 2-Ethyl-dG Adducts along Duplex DNA

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