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A Synthetic Fluorescent Mitochondria‐Targeted Sensor for Ratiometric Imaging of Calcium in Live Cells

Angewandte Chemie International Edition, 2019-07, Vol.58 (29), p.9917-9922

International ed. in English, 2019

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Resveratrol derivatives as a pharmacological tool

Annals of the New York Academy of Sciences, 2017-09, Vol.1403 (1), p.27-37

2017

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Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction

Cell reports (Cambridge), 2019-08, Vol.28 (8), p.1949-1960.e6

2019

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Altered MICOS Morphology and Mitochondrial Ion Homeostasis Contribute to Poly(GR) Toxicity Associated with C9-ALS/FTD

Cell reports (Cambridge), 2020-08, Vol.32 (5), p.107989-107989, Article 107989

2020

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LETM1-Mediated K+ and Na+ Homeostasis Regulates Mitochondrial Ca2+ Efflux

Frontiers in physiology, 2017-11, Vol.8, p.839-839

2017

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Esmethadone (REL-1017) and Other Uncompetitive NMDAR Channel Blockers May Improve Mood Disorders via Modulation of Synaptic Kinase-Mediated Signaling

International journal of molecular sciences, 2022-10, Vol.23 (20), p.12196

2022

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Small-Molecule Modulators of Mitochondrial Channels as Chemotherapeutic Agents

Cellular physiology and biochemistry, 2019, Vol.53 (S1), p.11-43

2019

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An agonist of the CXCR4 receptor accelerates the recovery from the peripheral neuroparalysis induced by Taipan snake envenomation

PLoS neglected tropical diseases, 2020-09, Vol.14 (9), p.e0008547

2020

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The mitochondrial ATP-dependent potassium channel (mitoK ATP ) controls skeletal muscle structure and function

Cell death & disease, 2024-01, Vol.15 (1), p.58-58, Article 58

2024

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Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo

Cell death & disease, 2022-12, Vol.13 (12), p.1055-19, Article 1055

2022

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Pharmacological modulation of Kv1.3 potassium channel selectively triggers pathological B lymphocyte apoptosis in vivo in a genetic CLL model

Journal of experimental & clinical cancer research, 2022-02, Vol.41 (1), p.64-64, Article 64

2022

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Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family

Redox biology, 2020-10, Vol.37, p.101705, Article 101705

2020

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N-Monosubstituted Methoxy-oligo(ethylene glycol) Carbamate Ester Prodrugs of Resveratrol

Molecules (Basel, Switzerland), 2015-09, Vol.20 (9), p.16085-16102

2015

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DA7R: A 7-Letter Zip Code to Target PDAC

Pharmaceutics, 2023-05, Vol.15 (5), p.1508

2023

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Novel Small Molecule Inhibitors That Prevent the Neuroparalysis of Tetanus Neurotoxin

Pharmaceuticals (Basel, Switzerland), 2021-11, Vol.14 (11), p.1134

2021

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Mitochondria-targeted resveratrol derivatives act as cytotoxic pro-oxidants

Current pharmaceutical design, 2014-01, Vol.20 (2), p.172

2014

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Drug–Drug Interaction Studies of Esmethadone (REL-1017) Involving CYP3A4- and CYP2D6-Mediated Metabolism

Drugs in R&D, 2024-03, Vol.24 (1), p.51-68

2024

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Pharmacological Comparative Characterization of REL-1017 (Esmethadone-HCl) and Other NMDAR Channel Blockers in Human Heterodimeric N-Methyl-D-Aspartate Receptors

Pharmaceuticals (Basel, Switzerland), 2022-08, Vol.15 (8), p.997

2022

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Inhibition of a Mitochondrial Potassium Channel in Combination with Gemcitabine and Abraxane Drastically Reduces Pancreatic Ductal Adenocarcinoma in an Immunocompetent Orthotopic Murine Model

Cancers, 2022-05, Vol.14 (11), p.2618

2022

Volltextzugriff (PDF)

The N-Methyl-D-Aspartate Receptor Blocker REL-1017 (Esmethadone) Reduces Calcium Influx Induced by Glutamate, Quinolinic Acid, and Gentamicin

Pharmaceuticals (Basel, Switzerland), 2022-07, Vol.15 (7), p.882

2022

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Novel Mitochondria-Targeted Furocoumarin Derivatives as Possible Anti-Cancer Agents

Frontiers in oncology, 2018-04, Vol.8, p.122-122

2018

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Targeting the Potassium Channel Kv1.3 Kills Glioblastoma Cells

Neuro-Signals, 2017, Vol.25 (1), p.26-38

2017

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New water-soluble carbamate ester derivatives of resveratrol

Molecules (Basel, Switzerland), 2014-10, Vol.19 (10), p.15900-15917

2014

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Mitochondrial Kv1.3 Channels as Target for Treatment of Multiple Myeloma

Cancers, 2022-04, Vol.14 (8), p.1955

2022

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A Synthetic Fluorescent Mitochondria‐Targeted Sensor for Ratiometric Imaging of Calcium in Live Cells

Resveratrol derivatives as a pharmacological tool

Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction

Altered MICOS Morphology and Mitochondrial Ion Homeostasis Contribute to Poly(GR) Toxicity Associated with C9-ALS/FTD

LETM1-Mediated K+ and Na+ Homeostasis Regulates Mitochondrial Ca2+ Efflux

Esmethadone (REL-1017) and Other Uncompetitive NMDAR Channel Blockers May Improve Mood Disorders via Modulation of Synaptic Kinase-Mediated Signaling

Small-Molecule Modulators of Mitochondrial Channels as Chemotherapeutic Agents

An agonist of the CXCR4 receptor accelerates the recovery from the peripheral neuroparalysis induced by Taipan snake envenomation

The mitochondrial ATP-dependent potassium channel (mitoK ATP ) controls skeletal muscle structure and function

Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo

Defective excitation-contraction coupling and mitochondrial respiration precede mitochondrial Ca2+ accumulation in spinobulbar muscular atrophy skeletal muscle

Pharmacological modulation of Kv1.3 potassium channel selectively triggers pathological B lymphocyte apoptosis in vivo in a genetic CLL model

Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family

N-Monosubstituted Methoxy-oligo(ethylene glycol) Carbamate Ester Prodrugs of Resveratrol

DA7R: A 7-Letter Zip Code to Target PDAC

Novel Small Molecule Inhibitors That Prevent the Neuroparalysis of Tetanus Neurotoxin

Mitochondria-targeted resveratrol derivatives act as cytotoxic pro-oxidants

Drug–Drug Interaction Studies of Esmethadone (REL-1017) Involving CYP3A4- and CYP2D6-Mediated Metabolism

Pharmacological Comparative Characterization of REL-1017 (Esmethadone-HCl) and Other NMDAR Channel Blockers in Human Heterodimeric N-Methyl-D-Aspartate Receptors

Inhibition of a Mitochondrial Potassium Channel in Combination with Gemcitabine and Abraxane Drastically Reduces Pancreatic Ductal Adenocarcinoma in an Immunocompetent Orthotopic Murine Model

The N-Methyl-D-Aspartate Receptor Blocker REL-1017 (Esmethadone) Reduces Calcium Influx Induced by Glutamate, Quinolinic Acid, and Gentamicin

Novel Mitochondria-Targeted Furocoumarin Derivatives as Possible Anti-Cancer Agents

Targeting the Potassium Channel Kv1.3 Kills Glioblastoma Cells

New water-soluble carbamate ester derivatives of resveratrol

Mitochondrial Kv1.3 Channels as Target for Treatment of Multiple Myeloma

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