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Hepatocyte growth factor/MET in cancer progression and biomarker discovery

Cancer science, 2017-03, Vol.108 (3), p.296-307

2017

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Transient IGF-1R inhibition combined with osimertinib eradicates AXL-low expressing EGFR mutated lung cancer

Nature communications, 2020-09, Vol.11 (1), p.4607-14, Article 4607

2020

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Hepatocyte growth factor in physiology and infectious diseases

Cytokine (Philadelphia, Pa.), 2017-10, Vol.98, p.97-106

2017

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Hepatocyte growth factor and the Met system as a mediator of tumor–stromal interactions

International journal of cancer, 2006-08, Vol.119 (3), p.477-483

2006

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Hepatocyte growth factor twenty years on: Much more than a growth factor

Journal of gastroenterology and hepatology, 2011-01, Vol.26 (s1), p.188-202

2011

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Hepatocyte growth factor and Met in drug discovery

Journal of biochemistry (Tokyo), 2015-05, Vol.157 (5), p.271-284

2015

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Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor

Nature chemical biology, 2019-06, Vol.15 (6), p.598

2019

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Lasso-grafting of macrocyclic peptide pharmacophores yields multi-functional proteins

Nature communications, 2021-03, Vol.12 (1), p.1543-1543, Article 1543

2021

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N‐glycosylation regulates MET processing and signaling

Cancer science, 2022-04, Vol.113 (4), p.1292-1304

2022

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Non-Small Cell Lung Cancer Cells Acquire Resistance to the ALK Inhibitor Alectinib by Activating Alternative Receptor Tyrosine Kinases

Cancer research (Chicago, Ill.), 2016-03, Vol.76 (6), p.1506-1516

2016

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Artificial human Met agonists based on macrocycle scaffolds

Nature communications, 2015-03, Vol.6 (1), p.6373-6373, Article 6373

2015

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Crosstalk to Stromal Fibroblasts Induces Resistance of Lung Cancer to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors

Clinical cancer research, 2009-11, Vol.15 (21), p.6630-6638

2009

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NK4 (HGF‐antagonist/angiogenesis inhibitor) in cancer biology and therapeutics

Cancer science, 2003-04, Vol.94 (4), p.321-327

2003

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Hepatocyte growth factor: Renotropic role and potential therapeutics for renal diseases

Kidney international, , Vol.59 (6), p.2023

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Dimer Interface in Natural Variant NK1 Is Dispensable for HGF-Dependent Met Receptor Activation

International journal of molecular sciences, 2021-08, Vol.22 (17), p.9240

2021

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Impaired ligand‐dependent MET activation caused by an extracellular SEMA domain missense mutation in lung cancer

Cancer science, 2019-10, Vol.110 (10), p.3340-3349

2019

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Dual blockade of MET and VEGFR2 signaling pathways as a potential therapeutic maneuver for peritoneal carcinomatosis in scirrhous gastric cancer

Biochemical and biophysical research communications, 2022-04, Vol.600, p.80-86

2022

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SRC kinase activator CDCP1 promotes hepatocyte growth factor–induced cell migration/invasion of a subset of breast cancer cells

The Journal of biological chemistry, 2022-03, Vol.298 (3), p.101630-101630, Article 101630

2022

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Insulin Suppresses Ubiquitination via the Deubiquitinating Enzyme Ubiquitin-Specific Protease 14, Independent of Proteasome Activity in H4IIEC3 Hepatocytes

The Journal of pharmacology and experimental therapeutics, 2023-04, Vol.385 (1), p.5

2023

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Two-Chain Mature Hepatocyte Growth Factor-Specific Positron Emission Tomography Imaging in Tumors Using 64Cu-Labeled HiP-8, a Nonstandard Macrocyclic Peptide Probe

Molecular pharmaceutics, 2023-04, Vol.20 (4), p.2029-2038

2023

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Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice

Molecular brain, 2009-03, Vol.2 (1), p.8-8, Article 8

2009

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Targeting the hepatocyte growth factor/Met pathway in cancer

Biochemical Society transactions, 2017-08, Vol.45 (4), p.855

2017

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The constitutive high-affinity Met-binding site in the kringle domain is dispensable for the signalling activity of hepatocyte growth factor

Journal of biochemistry (Tokyo), 2020-06, Vol.167 (6), p.577

2020

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Recent Insights into Human Endometrial Peptidases in Blastocyst Implantation via Shedding of Microvesicles

International journal of molecular sciences, 2021-12, Vol.22 (24), p.13479

2021

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Cross-activating c-Met/β1 integrin complex drives metastasis and invasive resistance in cancer

Proceedings of the National Academy of Sciences - PNAS, 2017-10, Vol.114 (41), p.E8685-E8694

2017

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Hepatocyte growth factor/MET in cancer progression and biomarker discovery

Transient IGF-1R inhibition combined with osimertinib eradicates AXL-low expressing EGFR mutated lung cancer

Hepatocyte growth factor in physiology and infectious diseases

Hepatocyte growth factor and the Met system as a mediator of tumor–stromal interactions

Hepatocyte growth factor twenty years on: Much more than a growth factor

Hepatocyte growth factor and Met in drug discovery

Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor

Lasso-grafting of macrocyclic peptide pharmacophores yields multi-functional proteins

N‐glycosylation regulates MET processing and signaling

Non-Small Cell Lung Cancer Cells Acquire Resistance to the ALK Inhibitor Alectinib by Activating Alternative Receptor Tyrosine Kinases

Artificial human Met agonists based on macrocycle scaffolds

Crosstalk to Stromal Fibroblasts Induces Resistance of Lung Cancer to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors

NK4 (HGF‐antagonist/angiogenesis inhibitor) in cancer biology and therapeutics

Hepatocyte growth factor: Renotropic role and potential therapeutics for renal diseases

Dimer Interface in Natural Variant NK1 Is Dispensable for HGF-Dependent Met Receptor Activation

Impaired ligand‐dependent MET activation caused by an extracellular SEMA domain missense mutation in lung cancer

Dual blockade of MET and VEGFR2 signaling pathways as a potential therapeutic maneuver for peritoneal carcinomatosis in scirrhous gastric cancer

SRC kinase activator CDCP1 promotes hepatocyte growth factor–induced cell migration/invasion of a subset of breast cancer cells

Insulin Suppresses Ubiquitination via the Deubiquitinating Enzyme Ubiquitin-Specific Protease 14, Independent of Proteasome Activity in H4IIEC3 Hepatocytes

Two-Chain Mature Hepatocyte Growth Factor-Specific Positron Emission Tomography Imaging in Tumors Using 64Cu-Labeled HiP-8, a Nonstandard Macrocyclic Peptide Probe

Tryptophan 2,3-dioxygenase is a key modulator of physiological neurogenesis and anxiety-related behavior in mice

Targeting the hepatocyte growth factor/Met pathway in cancer

The constitutive high-affinity Met-binding site in the kringle domain is dispensable for the signalling activity of hepatocyte growth factor

Recent Insights into Human Endometrial Peptidases in Blastocyst Implantation via Shedding of Microvesicles

Cross-activating c-Met/β1 integrin complex drives metastasis and invasive resistance in cancer

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