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Potassium-competitive acid blockers: Advanced therapeutic option for acid-related diseases

Pharmacology & therapeutics (Oxford), 2016-12, Vol.168, p.12-22

2016

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ASK1-MAP Kinase Cascades in Mammalian Stress Response

Journal of biochemistry (Tokyo), 2004-09, Vol.136 (3), p.261-265

2004

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A comparative study on the modes of action of TAK-438, a novel potassium-competitive acid blocker, and lansoprazole in primary cultured rabbit gastric glands

Biochemical pharmacology, 2011-05, Vol.81 (9), p.1145-1151

2011

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1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine monofumarate (TAK-438), a novel and potent potassium-competitive acid blocker for the treatment of acid-related diseases

The Journal of pharmacology and experimental therapeutics, 2010-10, Vol.335 (1), p.231-238

2010

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Radiographic Localization Study of a Novel Potassium-Competitive Acid Blocker, Vonoprazan, in the Rat Gastric Mucosa

Digestive diseases and sciences, 2016-07, Vol.61 (7), p.1888-1894

2016

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Discovery of a Novel Pyrrole Derivative 1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine Fumarate (TAK-438) as a Potassium-Competitive Acid Blocker (P-CAB)

Journal of medicinal chemistry, 2012-05, Vol.55 (9), p.4446-4456

2012

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Additional Estrogen Administration to Avoid Poor Outcomes Associated with a Thin Endometrium in Frozen Embryo Transfer

Fertility & reproduction, 2023-03, Vol.5 (1), p.61-66

2023

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Rare urogenital anomaly variant with a separated didelphic uterus and ipsilateral renal agenesis without hemivagina: A case report

Congenital anomalies, 2019-03, Vol.59 (2), p.47-48

2019

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Successful laparoscopic resection of virilizing ovarian steroid cell tumor, not otherwise specified, in a 22-year-old woman: a case report and evaluation of the steroidogenic pathway

FUKUSHIMA JOURNAL OF MEDICAL SCIENCE, 2019, Vol.65(3), pp.133-139

2019

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Daikenchuto (TU‐100) Suppresses Tumor Development in the Azoxymethane and APCmin/+ Mouse Models of Experimental Colon Cancer

Phytotherapy research, 2017-01, Vol.31 (1), p.90-99

2017

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A study comparing the antisecretory effect of TAK-438, a novel potassium-competitive acid blocker, with lansoprazole in animals

The Journal of pharmacology and experimental therapeutics, 2011-06, Vol.337 (3), p.797-804

2011

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Impact of Diagnosis and Treatment of Chronic Endometritis on Outcomes Before Starting Assisted Reproductive Technology: A Retrospective Study

Reproductive sciences (Thousand Oaks, Calif.), 2024-07

2024

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Consideration of low-invasive ICSI (NBP-ICSI) using a non bevel pipet

Fertility and sterility, 2019-09, Vol.112 (3), p.e280-e281

2019

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Septal Rupture During Early Pregnancy and Successful Delivery in Monozygotic Dichorionic Diamniotic Twin After a Single Blastocyst Transfer

Reproductive sciences (Thousand Oaks, Calif.), 2024, Vol.31 (1), p.122-127

2024

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Role of ADP-ribosylation Factor 6 (ARF6) in Gastric Acid Secretion

The Journal of biological chemistry, 2003-09, Vol.278 (38), p.36470-36475

2003

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Combination effects of alogliptin and pioglitazone on steatosis and hepatic fibrosis formation in a mouse model of non-alcoholic steatohepatitis

Biochemical and biophysical research communications, 2018-02, Vol.497 (1), p.207-213

2018

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Mo1146 Localization of a Novel Potassium Competitive Acid Blocker, Vonoprazan, in the Rat Gastric Mucosa: A Radiographic Study

Gastroenterology (New York, N.Y. 1943), 2015-04, Vol.148 (4), p.S-620-S-620

2015

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Discovery, synthesis, and structure-activity relations of 3,4-dihydro-1H-spiro(naphthalene-2,2′-piperidin)-1-ones as potassium-competitive acid blockers

Bioorganic & medicinal chemistry, 2017-07, Vol.25 (14), p.3719-3735

2017

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Exploration of pyrrole derivatives to find an effective potassium-competitive acid blocker with moderately long-lasting suppression of gastric acid secretion

Bioorganic & medicinal chemistry, 2017-07, Vol.25 (13), p.3447-3460

2017

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Prokinetic actions of luminally acting 5‐HT4 receptor agonists

Neurogastroenterology and motility, 2021-04, Vol.33 (4), p.e14026-n/a

2021

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Identification of a novel fluoropyrrole derivative as a potassium-competitive acid blocker with long duration of action

Bioorganic & medicinal chemistry, 2017-07, Vol.25 (13), p.3298-3314

2017

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Pharmacological characteristics and clinical efficacies of a novel potassium-competitive acid blocker, vonoprazan fumarate

Folia Pharmacologica Japonica, 2018, Vol.152(3), pp.104-110

2018

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Discovery, synthesis, and structure-activity relations of 3,4-dihydro-1 H -spiro(naphthalene-2,2′-piperidin)-1-ones as potassium-competitive acid blockers

Bioorganic & medicinal chemistry, 2017-07, Vol.25 (14), p.3719-3735

2017

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Pro-Kinetic Actions of Luminally-Acting 5-HT4 Receptor Agonists

Neurogastroenterology and motility, 2020-11, Vol.33 (4), p.e14026-e14026

2020

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Pharmacological and clinical profiles of a novel potassium-competitive acid blocker, vonoprazan fumarate (Takecab(®) 10 mg and 20 mg)

Nihon yakurigaku zasshi, 2015-11, Vol.146 (5), p.275-282

2015

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Potassium-competitive acid blockers: Advanced therapeutic option for acid-related diseases

ASK1-MAP Kinase Cascades in Mammalian Stress Response

A comparative study on the modes of action of TAK-438, a novel potassium-competitive acid blocker, and lansoprazole in primary cultured rabbit gastric glands

1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine monofumarate (TAK-438), a novel and potent potassium-competitive acid blocker for the treatment of acid-related diseases

Radiographic Localization Study of a Novel Potassium-Competitive Acid Blocker, Vonoprazan, in the Rat Gastric Mucosa

Discovery of a Novel Pyrrole Derivative 1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine Fumarate (TAK-438) as a Potassium-Competitive Acid Blocker (P-CAB)

Additional Estrogen Administration to Avoid Poor Outcomes Associated with a Thin Endometrium in Frozen Embryo Transfer

Rare urogenital anomaly variant with a separated didelphic uterus and ipsilateral renal agenesis without hemivagina: A case report

Successful laparoscopic resection of virilizing ovarian steroid cell tumor, not otherwise specified, in a 22-year-old woman: a case report and evaluation of the steroidogenic pathway

Daikenchuto (TU‐100) Suppresses Tumor Development in the Azoxymethane and APCmin/+ Mouse Models of Experimental Colon Cancer

A study comparing the antisecretory effect of TAK-438, a novel potassium-competitive acid blocker, with lansoprazole in animals

Impact of Diagnosis and Treatment of Chronic Endometritis on Outcomes Before Starting Assisted Reproductive Technology: A Retrospective Study

Consideration of low-invasive ICSI (NBP-ICSI) using a non bevel pipet

Septal Rupture During Early Pregnancy and Successful Delivery in Monozygotic Dichorionic Diamniotic Twin After a Single Blastocyst Transfer

Role of ADP-ribosylation Factor 6 (ARF6) in Gastric Acid Secretion

Combination effects of alogliptin and pioglitazone on steatosis and hepatic fibrosis formation in a mouse model of non-alcoholic steatohepatitis

Mo1146 Localization of a Novel Potassium Competitive Acid Blocker, Vonoprazan, in the Rat Gastric Mucosa: A Radiographic Study

Discovery, synthesis, and structure-activity relations of 3,4-dihydro-1H-spiro(naphthalene-2,2′-piperidin)-1-ones as potassium-competitive acid blockers

Exploration of pyrrole derivatives to find an effective potassium-competitive acid blocker with moderately long-lasting suppression of gastric acid secretion

Prokinetic actions of luminally acting 5‐HT4 receptor agonists

Identification of a novel fluoropyrrole derivative as a potassium-competitive acid blocker with long duration of action

Pharmacological characteristics and clinical efficacies of a novel potassium-competitive acid blocker, vonoprazan fumarate

Discovery, synthesis, and structure-activity relations of 3,4-dihydro-1 H -spiro(naphthalene-2,2′-piperidin)-1-ones as potassium-competitive acid blockers

Pro-Kinetic Actions of Luminally-Acting 5-HT4 Receptor Agonists

Pharmacological and clinical profiles of a novel potassium-competitive acid blocker, vonoprazan fumarate (Takecab(®) 10 mg and 20 mg)

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