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Structural requirements for binding of myelin basic protein (MBP) peptides to MHC II: effects on immune regulation

Current medicinal chemistry, 2005-01, Vol.12 (13), p.1521-1535

2005

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Role of the NH2-terminal domain of angiotensin II (ANG II) and [Sar1]angiotensin II on conformation and activity. NMR evidence for aromatic ring clustering and peptide backbone folding compared with [des-1,2,3]angiotensin II

The Journal of biological chemistry, 1994-02, Vol.269 (7), p.5303-5312

1994

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The design and synthesis of a potent Angiotensin II cyclic analogue confirms the ring cluster receptor conformation of the hormone Angiotensin II

Bioorganic & medicinal chemistry, 2000, Vol.8 (1), p.1-10

2000

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Conformational and biological studies for a pair of novel synthetic AT1 antagonists: stereoelectronic requirements for antihypertensive efficacy

Journal of pharmaceutical and biomedical analysis, 2003-04, Vol.31 (5), p.833-844

2003

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Structural comparison between type I and type II antagonists : Possible implications in the drug design of AT1 antagonists

Bioorganic & medicinal chemistry letters, 2000-04, Vol.10 (8), p.755-758

2000

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A putative bioactive conformation for the altered peptide ligand of myelin basic protein and inhibitor of experimental autoimmune encephalomyelitis [Arg91, Ala96] MBP87-99

Journal of molecular graphics & modelling, 2006-09, Vol.25 (1), p.17-29

2006

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Differences in Backbone Structure between Angiotensin II Agonists and Type I Antagonists

Journal of medicinal chemistry, 1995-11, Vol.38 (23), p.4660-4669

1995

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Synthesis and biological activities of angiotensin II, sarilesin, and sarmesin analogs containing Aze or Pip at position 7

Journal of medicinal chemistry, 1993-04, Vol.36 (7), p.904-911

1993

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Fluorescence properties of angiotensin II analogues in receptor-simulating environments: relationship between tyrosinate fluorescence lifetime and biological activity

Biochimica et biophysica acta, 1991-05, Vol.1065 (1), p.21-28

1991

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Role of myelin basic protein epitope MBP74-85 in experimental autoimmune encephalomyelitis: Elaboration of agonist and antagonist motifs

Drug development research, 1999-09, Vol.48 (1), p.1-5

1999

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Synthesis and Contractile Activities of Cyclic Thrombin Receptor-Derived Peptide Analogues with a Phe-Leu-Leu-Arg Motif: Importance of the Phe/Arg Relative Conformation and the Primary Amino Group for Activity

Journal of medicinal chemistry, 1996-08, Vol.39 (18), p.3585-3591

1996

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Design and Synthesis of a Potent Cyclic Analogue of the Myelin Basic Protein Epitope MBP72-85: Importance of the Ala81 Carboxyl Group and of a Cyclic Conformation for Induction of Experimental Allergic Encephalomyelitis

Journal of medicinal chemistry, 1999-04, Vol.42 (7), p.1170-1177

1999

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Comparison of Proposed Putative Active Conformations of Myelin Basic Protein Epitope 87−99 Linear Altered Peptide Ligands by Spectroscopic and Modelling Studies: The Role of Positions 91 and 96 in T-Cell Receptor Activation

Journal of medicinal chemistry, 2006-11, Vol.49 (23), p.6683-6691

2006

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Novel Synthesis of Cyclic Amide-Linked Analogs of Angiotensins II and III

Journal of medicinal chemistry, 1994-09, Vol.37 (18), p.2958-2969

1994

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Recognition of the encephalitogenic myelin basic protein (74-85) peptide by the immune system: importance of conformation

Proceedings of the Western Pharmacology Society, 1998, Vol.41, p.193

1998

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A new approach to angiotensin antagonists: Methylation of the tyrosine hydroxyl in angiotensin II

Life sciences (1973), 1984-01, Vol.34 (4), p.317-321

1984

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A cyclic angiotensin antagonist: [1,8-cysteine]angiotensin II

Journal of medicinal chemistry, 1984-01, Vol.27 (3), p.404-406

1984

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Influence of polyfluorination of the phenylalanine ring of angiotensin II on conformation and biological activity

Biochimica et biophysica acta, 1991-08, Vol.1079 (1), p.23-28

1991

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Structure elucidation and conformational analysis of gonadotropin releasing hormone and its novel synthetic analogue [Tyr(OMe)5, D-Lys6, Aze9NHet]GnRH : The importance of aromatic clustering in the receptor binding activity

European journal of medicinal chemistry, 1997-12, Vol.32 (12), p.927-940

1997

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Synthesis and study of the electrophoretic behavior of mannan conjugates with cyclic peptide analogue of myelin basic protein using lysine-glycine linker

Analytical biochemistry, 2005-12, Vol.347 (1), p.121-128

2005

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Tyrosinate fluorescence lifetimes for oxytocin and vasopressin in receptor-simulating environments: Relationship to biological activity and 1H-NMR data

Biochemical and biophysical research communications, 1990-09, Vol.171 (3), p.996-1001

1990

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Synthesis and biological activities of analogs of angiotensins II and III containing O-methyltyrosine and D-tryptophan

Journal of medicinal chemistry, 1985-06, Vol.28 (6), p.780-783

1985

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A putative bioactive conformation for the altered peptide ligand of myelin basic protein and inhibitor of experimental autoimmune encephalomyelitis [Arg super(91), Ala super(96)] MBP sub(87-99)

Journal of molecular graphics & modelling, 2006-09, Vol.25 (1), p.17-29

2006

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NMR studies on angiotensin II: Histidine and phenylalanine ring stacking and biological activity

Biochemical and biophysical research communications, 1984-07, Vol.122 (1), p.434-438

1984

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Proton magnetic resonance studies of angiotensin II conformation: cis-trans isomerism in sarcosine7-containing analogs

Archives of biochemistry and biophysics, 1986-07, Vol.248 (1), p.419-423

1986

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Structural requirements for binding of myelin basic protein (MBP) peptides to MHC II: effects on immune regulation

Role of the NH2-terminal domain of angiotensin II (ANG II) and [Sar1]angiotensin II on conformation and activity. NMR evidence for aromatic ring clustering and peptide backbone folding compared with [des-1,2,3]angiotensin II

The design and synthesis of a potent Angiotensin II cyclic analogue confirms the ring cluster receptor conformation of the hormone Angiotensin II

Conformational and biological studies for a pair of novel synthetic AT1 antagonists: stereoelectronic requirements for antihypertensive efficacy

Structural comparison between type I and type II antagonists : Possible implications in the drug design of AT1 antagonists

A putative bioactive conformation for the altered peptide ligand of myelin basic protein and inhibitor of experimental autoimmune encephalomyelitis [Arg91, Ala96] MBP87-99

Differences in Backbone Structure between Angiotensin II Agonists and Type I Antagonists

Synthesis and biological activities of angiotensin II, sarilesin, and sarmesin analogs containing Aze or Pip at position 7

Fluorescence properties of angiotensin II analogues in receptor-simulating environments: relationship between tyrosinate fluorescence lifetime and biological activity

Role of myelin basic protein epitope MBP74-85 in experimental autoimmune encephalomyelitis: Elaboration of agonist and antagonist motifs

Synthesis and Contractile Activities of Cyclic Thrombin Receptor-Derived Peptide Analogues with a Phe-Leu-Leu-Arg Motif: Importance of the Phe/Arg Relative Conformation and the Primary Amino Group for Activity

Design and Synthesis of a Potent Cyclic Analogue of the Myelin Basic Protein Epitope MBP72-85: Importance of the Ala81 Carboxyl Group and of a Cyclic Conformation for Induction of Experimental Allergic Encephalomyelitis

Comparison of Proposed Putative Active Conformations of Myelin Basic Protein Epitope 87−99 Linear Altered Peptide Ligands by Spectroscopic and Modelling Studies: The Role of Positions 91 and 96 in T-Cell Receptor Activation

Novel Synthesis of Cyclic Amide-Linked Analogs of Angiotensins II and III

Recognition of the encephalitogenic myelin basic protein (74-85) peptide by the immune system: importance of conformation

A new approach to angiotensin antagonists: Methylation of the tyrosine hydroxyl in angiotensin II

A cyclic angiotensin antagonist: [1,8-cysteine]angiotensin II

Influence of polyfluorination of the phenylalanine ring of angiotensin II on conformation and biological activity

Structure elucidation and conformational analysis of gonadotropin releasing hormone and its novel synthetic analogue [Tyr(OMe)5, D-Lys6, Aze9NHet]GnRH : The importance of aromatic clustering in the receptor binding activity

Synthesis and study of the electrophoretic behavior of mannan conjugates with cyclic peptide analogue of myelin basic protein using lysine-glycine linker

Tyrosinate fluorescence lifetimes for oxytocin and vasopressin in receptor-simulating environments: Relationship to biological activity and 1H-NMR data

Synthesis and biological activities of analogs of angiotensins II and III containing O-methyltyrosine and D-tryptophan

A putative bioactive conformation for the altered peptide ligand of myelin basic protein and inhibitor of experimental autoimmune encephalomyelitis [Arg super(91), Ala super(96)] MBP sub(87-99)

NMR studies on angiotensin II: Histidine and phenylalanine ring stacking and biological activity

Proton magnetic resonance studies of angiotensin II conformation: cis-trans isomerism in sarcosine7-containing analogs

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