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The Network of Glucokinase-Expressing Cells in Glucose Homeostasis and the Potential of Glucokinase Activators for Diabetes Therapy

Diabetes (New York, N.Y.), 2006-01, Vol.55 (1), p.1-12

2006

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Allosteric Activators of Glucokinase: Potential Role in Diabetes Therapy

Science (American Association for the Advancement of Science), 2003-07, Vol.301 (5631), p.370-373

2003

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Green Tea Polyphenols Modulate Insulin Secretion by Inhibiting Glutamate Dehydrogenase

The Journal of biological chemistry, 2006-04, Vol.281 (15), p.10214-10221

2006

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Structural and Functional Abnormalities in the Islets Isolated From Type 2 Diabetic Subjects

Diabetes (New York, N.Y.), 2004-03, Vol.53 (3), p.624-632

2004

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The MODY1 gene HNF-4α regulates selected genes involved in insulin secretion

The Journal of clinical investigation, 2005-04, Vol.115 (4), p.1006-1015

2005

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Neonatal Diabetes Mellitus Due to Complete Glucokinase Deficiency

The New England journal of medicine, 2001-05, Vol.344 (21), p.1588-1592

2001

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A Signaling Role of Glutamine in Insulin Secretion

The Journal of biological chemistry, 2004-04, Vol.279 (14), p.13393-13401

2004

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Foxa2 regulates multiple pathways of insulin secretion

The Journal of clinical investigation, 2004-08, Vol.114 (4), p.512-520

2004

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Familial Hyperinsulinism Caused by an Activating Glucokinase Mutation

The New England journal of medicine, 1998-01, Vol.338 (4), p.226-230

1998

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Pancreatic beta-cell glucokinase: closing the gap between theoretical concepts and experimental realities

Diabetes (New York, N.Y.), 1998-03, Vol.47 (3), p.307

1998

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Rapamycin Has a Deleterious Effect on MIN-6 Cells and Rat and Human Islets

Diabetes (New York, N.Y.), 2003-11, Vol.52 (11), p.2731-2739

2003

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Permanent neonatal diabetes caused by glucokinase deficiency: Inborn error of the glucose-insulin signaling pathway

Diabetes (New York, N.Y.), 2003-11, Vol.52 (11), p.2854-2860

2003

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Regulation of Leucine-stimulated Insulin Secretion and Glutamine Metabolism in Isolated Rat Islets

The Journal of biological chemistry, 2003-01, Vol.278 (5), p.2853-2858

2003

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Foxa2 Controls Pdx1 Gene Expression in Pancreatic β-Cells In Vivo

Diabetes (New York, N.Y.), 2002-08, Vol.51 (8), p.2546-2551

2002

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Tissue-specific deletion of Foxa2 in pancreatic beta cells results in hyperinsulinemic hypoglycemia

Genes & development, 2001-07, Vol.15 (13), p.1706-1715

2001

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Insights Into the Biochemical and Genetic Basis of Glucokinase Activation From Naturally Occurring Hypoglycemia Mutations

Diabetes (New York, N.Y.), 2003-09, Vol.52 (9), p.2433-2440

2003

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Glucokinase and glucose homeostasis: proven concepts and new ideas

Biochemical Society transactions, 2005-02, Vol.33 (Pt 1), p.306

2005

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The second activating glucokinase mutation (A456V): Implications for glucose homeostasis and diabetes therapy

Diabetes (New York, N.Y.), 2002-04, Vol.51 (4), p.1240-1246

2002

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Insights into the Structure and Regulation of Glucokinase from a Novel Mutation (V62M), Which Causes Maturity-onset Diabetes of the Young

The Journal of biological chemistry, 2005-04, Vol.280 (14), p.14105-14113

2005

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Mutants of glucokinase cause hypoglycaemia- and hyperglycaemia syndromes and their analysis illuminates fundamental quantitative concepts of glucose homeostasis

Diabetologia, 1999-10, Vol.42 (10), p.1175-1186

1999

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High prevalence of glucokinase mutations in Italian children with MODY. Influence on glucose tolerance, first-phase insulin response, insulin sensitivity and BMI

Diabetologia, 2001-07, Vol.44 (7), p.898-905

2001

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Glucose regulation of glutaminolysis and its role in insulin secretion

Diabetes (New York, N.Y.), 1999-08, Vol.48 (8), p.1535

1999

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Analysis of upstream glucokinase promoter activity in transgenic mice and identification of glucokinase in rare neuroendocrine cells in the brain and gut

The Journal of biological chemistry, 1994-02, Vol.269 (5), p.3641-3654

1994

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Distinguishing Features of Leucine and α-Ketoisocaproate Sensing in Pancreatic β-Cells

Endocrinology (Philadelphia), 2003-05, Vol.144 (5), p.1949-1957

2003

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Structural model of human glucokinase in complex with glucose and ATP: implications for the mutants that cause hypo- and hyperglycemia

Diabetes (New York, N.Y.), 1999-09, Vol.48 (9), p.1698

1999

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The Network of Glucokinase-Expressing Cells in Glucose Homeostasis and the Potential of Glucokinase Activators for Diabetes Therapy

Allosteric Activators of Glucokinase: Potential Role in Diabetes Therapy

Green Tea Polyphenols Modulate Insulin Secretion by Inhibiting Glutamate Dehydrogenase

Structural and Functional Abnormalities in the Islets Isolated From Type 2 Diabetic Subjects

The MODY1 gene HNF-4α regulates selected genes involved in insulin secretion

Neonatal Diabetes Mellitus Due to Complete Glucokinase Deficiency

A Signaling Role of Glutamine in Insulin Secretion

Foxa2 regulates multiple pathways of insulin secretion

Familial Hyperinsulinism Caused by an Activating Glucokinase Mutation

Pancreatic beta-cell glucokinase: closing the gap between theoretical concepts and experimental realities

Rapamycin Has a Deleterious Effect on MIN-6 Cells and Rat and Human Islets

Permanent neonatal diabetes caused by glucokinase deficiency: Inborn error of the glucose-insulin signaling pathway

Regulation of Leucine-stimulated Insulin Secretion and Glutamine Metabolism in Isolated Rat Islets

Foxa2 Controls Pdx1 Gene Expression in Pancreatic β-Cells In Vivo

Tissue-specific deletion of Foxa2 in pancreatic beta cells results in hyperinsulinemic hypoglycemia

Insights Into the Biochemical and Genetic Basis of Glucokinase Activation From Naturally Occurring Hypoglycemia Mutations

Glucokinase and glucose homeostasis: proven concepts and new ideas

The second activating glucokinase mutation (A456V): Implications for glucose homeostasis and diabetes therapy

Insights into the Structure and Regulation of Glucokinase from a Novel Mutation (V62M), Which Causes Maturity-onset Diabetes of the Young

Mutants of glucokinase cause hypoglycaemia- and hyperglycaemia syndromes and their analysis illuminates fundamental quantitative concepts of glucose homeostasis

High prevalence of glucokinase mutations in Italian children with MODY. Influence on glucose tolerance, first-phase insulin response, insulin sensitivity and BMI

Glucose regulation of glutaminolysis and its role in insulin secretion

Analysis of upstream glucokinase promoter activity in transgenic mice and identification of glucokinase in rare neuroendocrine cells in the brain and gut

Distinguishing Features of Leucine and α-Ketoisocaproate Sensing in Pancreatic β-Cells

Structural model of human glucokinase in complex with glucose and ATP: implications for the mutants that cause hypo- and hyperglycemia

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