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Functional monoclonal antibody acts as a biased agonist by inducing internalization of metabotropic glutamate receptor 7

British journal of pharmacology, 2012-12, Vol.167 (7), p.1448-1466

2012

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Apolipoprotein M can discriminate HNF1A-MODY from Type 1 diabetes

Diabetic medicine, 2013-02, Vol.30 (2), p.246-250

2013

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Multimodal imaging of pancreatic beta cells in vivo by targeting transmembrane protein 27 (TMEM27)

Diabetologia, 2012-09, Vol.55 (9), p.2407-2416

2012

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4-aminoquinoline analogs of chloroquine with shortened side chains retain activity against chloroquine-resistant Plasmodium falciparum

Antimicrobial Agents and Chemotherapy, 1996-08, Vol.40 (8), p.1846-1854

1996

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Hematin Polymerization Assay as a High-Throughput Screen for Identification of New Antimalarial Pharmacophores

Antimicrobial Agents and Chemotherapy, 2000-10, Vol.44 (10), p.2638-2644

2000

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The N’-Terminal Domain of Glyceraldehyde-3-Phosphate Dehydrogenase of the Apicomplexan Plasmodium falciparum Mediates GTPase Rab2-Dependent Recruitment to Membranes

Biological chemistry, 2003-08, Vol.384 (8), p.1227-1237

2003

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Identification of an antimalarial synthetic trioxolane drug development candidate

Nature, 2004-08, Vol.430 (7002), p.900-904

2004

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Analysis of adult neurogenesis: evidence for a prominent "non-neurogenic" DCX-protein pool in rodent brain

PloS one, 2013-05, Vol.8 (5), p.e59269-e59269

2013

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Elimination of P. berghei liver stages is independent of Fas (CD95/Apo‐I) or perforin‐mediated cytotoxicity

Parasite immunology, 1997-03, Vol.19 (3), p.145-148

1997

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Structure of the micro-opioid receptor-Gi protein complex

Nature (London), 2018, Vol.558 (7711), p.547-552

2018

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A malaria T-cell epitope recognized in association with most mouse and human MHC class II molecules

Nature (London), 1988-12, Vol.336 (6201), p.778-780

1988

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Ability of recombinant or native proteins to protect monkeys against heterologous challenge with Plasmodium falciparum

Infection and Immunity, 1991-10, Vol.59 (10), p.3498-3503

1991

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Rhoptry-associated protein 1-binding monoclonal antibody raised against a heterologous peptide sequence inhibits Plasmodium falciparum growth in vitro

Infection and immunity, 2001-04, Vol.69 (4), p.2558-2568

2001

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An Assessment of Drug-Haematin Binding as a Mechanism for Inhibition of Haematin Polymerisation by Quinoline Antimalarials

Biochemical pharmacology, 1998-03, Vol.55 (6), p.727-736

1998

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Spiro and Dispiro-1,2,4-trioxolanes as Antimalarial Peroxides: Charting a Workable Structure−Activity Relationship Using Simple Prototypes

Journal of medicinal chemistry, 2005-07, Vol.48 (15), p.4953-4961

2005

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Short report: floxacrine analog WR 243251 inhibits hematin polymerization

The American journal of tropical medicine and hygiene, 2001-07, Vol.65 (1), p.19-20

2001

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In vitro assessment of the pharmacodynamic properties of DB75, piperaquine, OZ277 and OZ401 in cultures of Plasmodium falciparum

Journal of antimicrobial chemotherapy, 2008-11, Vol.62 (5), p.1061-1064

2008

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A Common Mechanism for Blockade of Heme Polymerization by Antimalarial Quinolines

The Journal of biological chemistry, 1998-11, Vol.273 (47), p.31103-31107

1998

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Effect of functional group polarity on the antimalarial activity of spiro and dispiro-1,2,4-trioxolanes

Bioorganic & medicinal chemistry, 2006-09, Vol.14 (18), p.6368-6382

2006

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Malarial haemozoin/β-haematin supports haem polymerization in the absence of protein

Nature (London), 1995-03, Vol.374 (6519), p.269-271

1995

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Apolipoprotein M can discriminate HNF 1A‐ MODY from Type 1 diabetes

Diabetic medicine, 2013-02, Vol.30 (2), p.246-250

2013

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Structural Specificity of Chloroquine−Hematin Binding Related to Inhibition of Hematin Polymerization and Parasite Growth

Journal of medicinal chemistry, 1999-11, Vol.42 (22), p.4630-4639

1999

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Use of Prior Vaccinations for the Development of New Vaccines

Science (American Association for the Advancement of Science), 1990-07, Vol.249 (4967), p.423-425

1990

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Safety, immunogenicity, and pilot efficacy of Plasmodium falciparum sporozoite and asexual blood-stage combination vaccine in Swiss adults

The American journal of tropical medicine and hygiene, 1995-10, Vol.53 (4), p.423-431

1995

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Synthesis and immunological characterization of 104-mer and 102-mer peptides corresponding to the N- and C-terminal regions of the Plasmodium falciparum CS protein

Molecular immunology, 1995-12, Vol.32 (17), p.1301-1309

1995

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Functional monoclonal antibody acts as a biased agonist by inducing internalization of metabotropic glutamate receptor 7

Apolipoprotein M can discriminate HNF1A-MODY from Type 1 diabetes

Multimodal imaging of pancreatic beta cells in vivo by targeting transmembrane protein 27 (TMEM27)

4-aminoquinoline analogs of chloroquine with shortened side chains retain activity against chloroquine-resistant Plasmodium falciparum

Hematin Polymerization Assay as a High-Throughput Screen for Identification of New Antimalarial Pharmacophores

The N’-Terminal Domain of Glyceraldehyde-3-Phosphate Dehydrogenase of the Apicomplexan Plasmodium falciparum Mediates GTPase Rab2-Dependent Recruitment to Membranes

Identification of an antimalarial synthetic trioxolane drug development candidate

Analysis of adult neurogenesis: evidence for a prominent "non-neurogenic" DCX-protein pool in rodent brain

Elimination of P. berghei liver stages is independent of Fas (CD95/Apo‐I) or perforin‐mediated cytotoxicity

Structure of the micro-opioid receptor-Gi protein complex

A malaria T-cell epitope recognized in association with most mouse and human MHC class II molecules

Ability of recombinant or native proteins to protect monkeys against heterologous challenge with Plasmodium falciparum

Rhoptry-associated protein 1-binding monoclonal antibody raised against a heterologous peptide sequence inhibits Plasmodium falciparum growth in vitro

An Assessment of Drug-Haematin Binding as a Mechanism for Inhibition of Haematin Polymerisation by Quinoline Antimalarials

Spiro and Dispiro-1,2,4-trioxolanes as Antimalarial Peroxides: Charting a Workable Structure−Activity Relationship Using Simple Prototypes

Short report: floxacrine analog WR 243251 inhibits hematin polymerization

In vitro assessment of the pharmacodynamic properties of DB75, piperaquine, OZ277 and OZ401 in cultures of Plasmodium falciparum

A Common Mechanism for Blockade of Heme Polymerization by Antimalarial Quinolines

Effect of functional group polarity on the antimalarial activity of spiro and dispiro-1,2,4-trioxolanes

Malarial haemozoin/β-haematin supports haem polymerization in the absence of protein

Apolipoprotein M can discriminate HNF 1A‐ MODY from Type 1 diabetes

Structural Specificity of Chloroquine−Hematin Binding Related to Inhibition of Hematin Polymerization and Parasite Growth

Use of Prior Vaccinations for the Development of New Vaccines

Safety, immunogenicity, and pilot efficacy of Plasmodium falciparum sporozoite and asexual blood-stage combination vaccine in Swiss adults

Synthesis and immunological characterization of 104-mer and 102-mer peptides corresponding to the N- and C-terminal regions of the Plasmodium falciparum CS protein

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